Questions and Answers
What is the main function of CD8+ cytotoxic T lymphocytes (CTLs)?
Kill infected cells
What is the role of IL-2 in the proliferation of T cells?
Initiates proliferation
Which molecule on antigen-presenting cells (APCs) activates MHC class II restricted T cells?
ICAM-1
What is the consequence of T cells recognizing antigens without costimulation?
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What is the function of B7-1 (CD90) in the interaction between class II MHC APCs and CD4+ T cells?
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What is the end result of signal transduction in a T lymphocyte?
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Which molecule binds to CD28 on T cell surfaces during signal transduction after antigen recognition?
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What happens if a naive T cell recognizes an antigen without co-stimulation?
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What is the main role of Intercellular Adhesion Molecule-1 (ICAM-1) in T-cell mediated host defense?
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At which stage do naive T cells require a second costimulatory signal for their proliferation and differentiation?
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Which type of T cell is responsible for killing infected cells containing microbial proteins in the cytosol?
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What is the primary function of CD4+ helper T cells in an immune response?
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Which subset of effector T cells is responsible for recruiting eosinophils to destroy helminthic parasites?
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What is the primary role of CD8+ T cells in the immune response?
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Which effector T cell subset secretes cytokines that recruit leukocytes and activate phagocytes to kill microbes?
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What is the effector function of Th2 subset effector cells?
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In an infection site, which T cell subset is specific to leukocyte recruitment?
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What is the main function of CD4+ cells in an immune response?
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