T Cell Effector Function Quiz
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T Cell Effector Function Quiz

Created by
@PerfectBowenite

Questions and Answers

What is the main function of CD8+ cytotoxic T lymphocytes (CTLs)?

Kill infected cells

What is the role of IL-2 in the proliferation of T cells?

Initiates proliferation

Which molecule on antigen-presenting cells (APCs) activates MHC class II restricted T cells?

ICAM-1

What is the consequence of T cells recognizing antigens without costimulation?

<p>Immune tolerance</p> Signup and view all the answers

What is the function of B7-1 (CD90) in the interaction between class II MHC APCs and CD4+ T cells?

<p>Activates T cell response</p> Signup and view all the answers

What is the end result of signal transduction in a T lymphocyte?

<p>Synthesis of toxins in CTLs</p> Signup and view all the answers

Which molecule binds to CD28 on T cell surfaces during signal transduction after antigen recognition?

<p>B7 costimulatory proteins</p> Signup and view all the answers

What happens if a naive T cell recognizes an antigen without co-stimulation?

<p>Development of tolerance</p> Signup and view all the answers

What is the main role of Intercellular Adhesion Molecule-1 (ICAM-1) in T-cell mediated host defense?

<p>Facilitate binding to APCs</p> Signup and view all the answers

At which stage do naive T cells require a second costimulatory signal for their proliferation and differentiation?

<p>Interaction with class II MHC APCs</p> Signup and view all the answers

Which type of T cell is responsible for killing infected cells containing microbial proteins in the cytosol?

<p>CD8+ cytotoxic T lymphocyte (CTL)</p> Signup and view all the answers

What is the primary function of CD4+ helper T cells in an immune response?

<p>Recruiting and activating phagocytes to destroy microbes</p> Signup and view all the answers

Which subset of effector T cells is responsible for recruiting eosinophils to destroy helminthic parasites?

<p>Th2</p> Signup and view all the answers

What is the primary role of CD8+ T cells in the immune response?

<p>Killing infected cells with microbial antigens in the cytosol</p> Signup and view all the answers

Which effector T cell subset secretes cytokines that recruit leukocytes and activate phagocytes to kill microbes?

<p>Th1</p> Signup and view all the answers

What is the effector function of Th2 subset effector cells?

<p>Recruiting eosinophils to destroy parasites</p> Signup and view all the answers

In an infection site, which T cell subset is specific to leukocyte recruitment?

<p>Th1</p> Signup and view all the answers

What is the main function of CD4+ cells in an immune response?

<p>&quot;Helping&quot; recruit other leukocytes to infection sites</p> Signup and view all the answers

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