Cell-Mediated Effector Responses and TH-Cell Differentiation Quiz

LFA-1 integrin is a receptor that binds to ICAM molecules.

Perforin creates pores in the target cell membrane allowing granzymes to enter.

CTLs and NK cells use similar mechanisms like perforin and granzymes for killing target cells.

NK cells, macrophages, neutrophils, eosinophils eliminate pathogens using lytic enzymes.

Direct killing by CTLs or NK cells helps remove pathogens.

B cells act as bridging cells in cellular responses.

T cells activate macrophages to eliminate intracellular pathogens.

IL-12 and IL-15 cytokines regulate NK cell activation.

Antigen recognition enhances LFA-1 integrin's binding strength.

Granzymes cause DNA fragmentation in target cells, without protein synthesis.

Helper T cells produce specific cytokine profiles.

CTLs recognize foreign antigens presented on MHC class I molecules via their TCR.

IL-2 induces proliferation of CTLs during activation.

NK cells identify targets using activating and inhibitory receptors.

CTLs use the perforin/granzyme pathways to destroy target cells.

TH17 subset produces cytokines that influence inflammation and immune response.

TFH cells regulate unique processes within the immune system.

TREG cells regulate immune responses within the body.

ADCC and IgE activation of eosinophils combat helminthic infections.

Conjugate formation is an early step in CTL target cell destruction.