Podcast
Questions and Answers
What is the primary purpose of the costimulatory signals provided by APCs to T cells?
What is the primary purpose of the costimulatory signals provided by APCs to T cells?
- To provide the initial signal for T cell activation
- To ensure that T cells are maximally activated by microbial antigens and not by harmless foreign substances (correct)
- To trigger the release of cytokines like IL-2 that stimulate T cell proliferation
- To increase the affinity of the LFA-1 integrin on naive T cells
What is the role of adhesion molecules like LFA-1 on T cells during the T cell response?
What is the role of adhesion molecules like LFA-1 on T cells during the T cell response?
- They trigger the release of cytokines like IL-2 that stimulate T cell proliferation
- They provide the initial signal for T cell activation
- They increase the strength of binding between T cells and APCs when the T cell sees an antigen (correct)
- They are responsible for the migration of effector T cells
What is the primary function of the biochemical signals triggered by the TCR complex and the CD4/CD8 coreceptor?
What is the primary function of the biochemical signals triggered by the TCR complex and the CD4/CD8 coreceptor?
- To trigger the release of cytokines like IL-2 that stimulate T cell proliferation
- To increase the affinity of the LFA-1 integrin on naive T cells
- To provide the initiating signal for T cell activation (correct)
- To ensure that naive T lymphocytes are activated maximally by microbial antigens and not by harmless foreign substances
What is the primary function of the memory T cells that remain in the system after an immune response?
What is the primary function of the memory T cells that remain in the system after an immune response?
What is the primary difference in the circulation and migration patterns between naive and effector T cells?
What is the primary difference in the circulation and migration patterns between naive and effector T cells?
What is the primary function of the CD4 and CD8 coreceptors on T cells during antigen recognition?
What is the primary function of the CD4 and CD8 coreceptors on T cells during antigen recognition?
What is the major role of T-cells in cell-mediated immunity?
What is the major role of T-cells in cell-mediated immunity?
Which of the following is NOT a phase of T cell response?
Which of the following is NOT a phase of T cell response?
What initiates the proliferation and differentiation of Naive T lymphocytes?
What initiates the proliferation and differentiation of Naive T lymphocytes?
What is the interaction required for destroying cancer cells in cell-mediated immunity?
What is the interaction required for destroying cancer cells in cell-mediated immunity?
When do effector T cells perform their functions in cell-mediated immunity?
When do effector T cells perform their functions in cell-mediated immunity?
What do T lymphocytes assist B cells in producing as part of humoral immune responses?
What do T lymphocytes assist B cells in producing as part of humoral immune responses?
