Disorders of Hemostasis NRAN 80413 Quiz
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Disorders of Hemostasis NRAN 80413 Quiz

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Questions and Answers

What is the target MAP during resuscitation?

60 mmHg

What is the platelet count target during resuscitation?

More than 50x10^9 /L

What is the expected INR value during resuscitation?

< 1.5

In the context of Hemophilia, which coagulation factor deficiency leads to Hemophilia A?

<p>Factor VIII deficiency</p> Signup and view all the answers

What is the expected pH range during resuscitation?

<p>$7.35-7.45$</p> Signup and view all the answers

Why is maintaining a Core temperature above 35 degrees C important during resuscitation?

<p>It improves oxygen delivery</p> Signup and view all the answers

What is the difference between sickle cell trait and sickle cell disease?

<p>Sickle cell trait involves having only one copy of the abnormal gene, while sickle cell disease involves having two copies.</p> Signup and view all the answers

What is the effect of reduced PaO2 in people with sickle cell disease?

<p>Causes vasoconstriction</p> Signup and view all the answers

What should be avoided in a patient with sickle cell disease?

<p>Dehydration and hypoxia</p> Signup and view all the answers

What are the 4 classes of hemorrhage?

<p>Class I, Class II, Class III, Class IV</p> Signup and view all the answers

What is the ABC Score?

<p>A scoring system used in activating massive transfusions</p> Signup and view all the answers

What are the targets of resuscitation when performing MTP?

<p>To achieve hemostasis and correct coagulopathy</p> Signup and view all the answers

Which disorder is characterized by intravascular coagulation activation with microvascular thrombi formation, leading to bleeding and end-organ complications?

<p>Disseminated Intravascular Coagulation</p> Signup and view all the answers

What does DIC result from?

<p>Disorganized clotting and fibrinolysis</p> Signup and view all the answers

What is the primary goal of Massive Blood Transfusion (MBT)?

<p>To rapidly deliver blood products to treat acute coagulopathy</p> Signup and view all the answers

Which condition is known for sickling of red blood cells at low oxygen levels, leading to tissue perfusion impairment and intense pain, especially in bones and joints?

<p>Sickle cell disease</p> Signup and view all the answers

Which complication of Sickle Cell Disease (SCD) involves the spleen removing red blood cells from circulation faster than they are produced?

<p>Sequestration crisis</p> Signup and view all the answers

What is the main reason for the implementation of Massive Transfusion Protocol (MTP) in trauma situations?

<p>To establish communication with the blood bank and trauma team</p> Signup and view all the answers

Which of the following indicators is typically elevated in a patient with Acute Disseminated Intravascular Coagulation (DIC)?

<p>Increased D-Dimer and Fibrin Degradation Products (FDPs)</p> Signup and view all the answers

In the context of anesthetic management, what issue arises with stored blood that is highlighted in the text?

<p>Hyperkalemia</p> Signup and view all the answers

What is the primary goal of transfusion protocols according to the text?

<p>To achieve hemostasis</p> Signup and view all the answers

What blood product plays a crucial role during Massive Transfusion Protocol (MTP)?

<p>Fresh frozen plasma</p> Signup and view all the answers

Which of the following is a correct target during resuscitation in Massive Transfusion Protocol (MTP)?

<p>MAP 60 mmHg</p> Signup and view all the answers

Which class of hemorrhage involves up to 30% blood volume loss and moderate tachycardia?

<p>Class II</p> Signup and view all the answers

Sickle cell trait patients with a PaO2 of > 35 mmHg will not advance to what condition?

<p>Sickle cell crisis</p> Signup and view all the answers

Patients with sickle cell trait have a higher risk of developing sickle cell disease compared to the general population.

<p>False</p> Signup and view all the answers

The goal of transfusion protocols is to restore normal coagulation parameters in patients.

<p>False</p> Signup and view all the answers

Massive transfusion protocols involve the use of blood products like platelets, cryoprecipitate, and fresh frozen plasma.

<p>True</p> Signup and view all the answers

A Class II hemorrhage involves up to 40% blood volume loss and mild tachycardia.

<p>False</p> Signup and view all the answers

The ABC Score is used in the activation of Massive Transfusion Protocols (MTP) to assess the severity of hemorrhage.

<p>False</p> Signup and view all the answers

Stored blood may have increased levels of potassium due to potassium loss during storage.

<p>False</p> Signup and view all the answers

Disseminated Intravascular Coagulation is characterized by microvascular thrombi formation, leading to end-organ complications and simultaneous bleeding.

<p>True</p> Signup and view all the answers

Hemophilia A involves the spleen removing red blood cells from circulation faster than they are produced.

<p>False</p> Signup and view all the answers

Maintaining a core temperature above 35 degrees Celsius is important during resuscitation to prevent hypothermia-related coagulopathy.

<p>True</p> Signup and view all the answers

$MBT$ stands for Major Bleeding Threshold, which is crucial in guiding the initiation of transfusion protocols.

<p>False</p> Signup and view all the answers

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