Podcast
Questions and Answers
What is the main function of platelets in haemostasis?
What is the main function of platelets in haemostasis?
- Produce coagulation factors
- Initiate the coagulation process
- Aggregate at sites of vessel injury to form the primary haemostatic plug (correct)
- Limit coagulation throughout the body
Which component is responsible for limiting fibrin deposition at the site of injury?
Which component is responsible for limiting fibrin deposition at the site of injury?
- Coagulation factors
- Platelets
- Blood vessels
- Fibrinolysis (correct)
What is the role of intact vascular endothelium in the haemostasis process?
What is the role of intact vascular endothelium in the haemostasis process?
- Inhibit coagulation (correct)
- Stabilize the primary haemostatic plug
- Limit coagulation throughout the body
- Initiate coagulation
Which factor is mainly responsible for activating coagulation when tissue is injured?
Which factor is mainly responsible for activating coagulation when tissue is injured?
What is the main function of coagulation inhibitors in haemostasis?
What is the main function of coagulation inhibitors in haemostasis?
Which screening test measures the activity of factors II, V, VII, and X?
Which screening test measures the activity of factors II, V, VII, and X?
What does APTT measure?
What does APTT measure?
What does a mixing study involving a 1:1 ratio mix with normal plasma distinguish between?
What does a mixing study involving a 1:1 ratio mix with normal plasma distinguish between?
Which factor deficiency can lead to easy bruising, hemarthrosis, mouth ulceration, and intramuscular hematoma?
Which factor deficiency can lead to easy bruising, hemarthrosis, mouth ulceration, and intramuscular hematoma?
What is the most common severe inherited bleeding disorder due to deficiencies of F8?
What is the most common severe inherited bleeding disorder due to deficiencies of F8?
At what factor level may mild deficiency of hemophilia be asymptomatic or require significant trauma to bleed?
At what factor level may mild deficiency of hemophilia be asymptomatic or require significant trauma to bleed?
What is the function of Von Willebrand factor (VWF) in plasma?
What is the function of Von Willebrand factor (VWF) in plasma?
What is the clinical manifestation of Von Willebrand disease (VWD)?
What is the clinical manifestation of Von Willebrand disease (VWD)?
What may be required for prophylaxis in severe hemophilia to prevent spontaneous bleeding and early joint deformities?
What may be required for prophylaxis in severe hemophilia to prevent spontaneous bleeding and early joint deformities?
What complications may arise from Von Willebrand disease?
What complications may arise from Von Willebrand disease?
