30 Questions
Where is the phospholipid cardiolipin concentrated?
Inner mitochondrial membrane
Which complex of the respiratory chain is known as Cytochrome c oxidase?
Complex IV
Where are the mobile components of the respiratory chain located?
Inner mitochondrial membrane
What happens when electrons flow through the respiratory chain?
Reduction of O2 to H2O
What is the function of ATP synthase in cellular respiration?
Convert ADP to ATP using proton gradient
Which enzyme is a component of both the Krebs cycle and the respiratory chain?
Succinate dehydrogenase complex
Where are electrons transferred into the mitochondria via shuttle systems?
Cytosol
What is the main function of the Malate-Aspartate Shuttle system?
Transfer electrons to complex I in the respiratory chain
Which organelle is involved in the Glycerol 3-P Shuttle system?
Mitochondria
What is the role of dihydroxyacetone phosphate in the Glycerol 3-P Shuttle system?
Accept reducing equivalents from NADH+H
Which enzyme catalyzes the reaction of producing glycerol-3-phosphate in the Glycerol 3-P Shuttle system?
Cytosolic glycerol 3-phosphate dehydrogenase
In which tissues is the Malate-Aspartate Shuttle system active?
Liver, kidney, and heart
What is the function of the glycerol 3-phosphate dehydrogenase isozyme?
It transfers reducing equivalents from glycerol 3-phosphate to ubiquinone (coenzyme Q)
Which complexes act as proton pumps during electron transport?
Complexes I, III, and IV
Why does the proton motive force accumulate in the intermembrane space?
The inner mitochondrial membrane is impermeable to ions and protons
What drives the ATP synthase (complex V) to synthesize ATP?
The proton motive force in the intermembrane space
Which subunit of the ATP synthase is responsible for ATP synthesis?
F1
How many ATP molecules are produced for each molecule of substrate oxidized via Complex I?
2.5 ATP
What is the role of FADH2 in the reactions involving complex II or coenzyme Q?
Donating electrons
How many moles of ATP are formed when 2 moles of the substrate are oxidized?
4.5
What controls the rate of respiration in mitochondria?
Availability of ADP
Why is oxidation tightly coupled with phosphorylation in oxidative phosphorylation?
To facilitate electron transport
Which specialized carrier is responsible for transporting ADP and Pi into mitochondria?
Adenine nucleotide translocase
What does an adenine nucleotide antiporter import into the mitochondria matrix?
One ADP molecule
Which of the following correctly describes the role of coenzyme Q in the electron transport chain?
It shuttles electrons between Complex I/II and Complex III
Which of the following complexes in the electron transport chain does NOT contribute to the proton gradient across the inner mitochondrial membrane?
Complex IV
What is the primary function of the proton gradient generated by the electron transport chain?
To drive the synthesis of ATP via ATP synthase
Which of the following statements correctly describes the oxidative phase of the respiratory chain?
It involves the transfer of electrons from NADH and FADH2 to oxygen
Which of the following metal ions plays a crucial role in facilitating electron flow in the respiratory chain complexes?
Iron-sulfur (Fe-S)
How many protons are pumped into the intermembrane space of the mitochondria by Complex I and Complex III combined?
8
Test your knowledge about the components of the respiratory chain, including Complex I to Complex V, coenzyme Q, and the role of cardiolipin in the inner membrane. Learn about the enzymes involved in ATP synthesis and electron transport.
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