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Complex IV and Electron Flow in Respiratory Chain

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30 Questions

Where is the phospholipid cardiolipin concentrated?

Inner mitochondrial membrane

Which component of the respiratory chain is also a part of the Krebs cycle?

Complex II

Where are the mobile components of the respiratory chain located?

Inner mitochondrial membrane

What is the final result when electrons flow through the respiratory chain?

Reduction of O2 to H2O

Which protein complex is responsible for transferring electrons from NADH to Ubiquinone?

Complex I

What is the role of Cytochrome c in the respiratory chain?

Transferring electrons from Complex III to Complex IV

What is the role of ATP synthase in the electron transport chain?

Synthesizing ATP using the electrochemical potential difference

Which component acts as the 'receptionist' of the respiratory chain?

Coenzyme Q

Where does the flow of electrons in the respiratory chain ultimately lead to?

O2 (final electron acceptor)

What is the main function of Fe, S, and Cu ions in the electron transport chain complexes?

Accelerating/facilitating electron flow

How many places in the respiratory chain pump protons into the intermembrane space?


Which phase of the respiratory chain involves the formation of water as a result of electron flow to O2?

Oxidative phosphorylation

Where does the electron pair carried by NADH+H+ enter the respiratory chain?

Complex I

Where does the electron pair carried by FADH2 enter the respiratory chain?

Complex II

How many protons are pumped into the intermembrane space when an electron pair enters via NADH+H+?


How many protons are pumped into the intermembrane space when an electron pair enters via FADH2?


What is the primary function of NADH+H+ in glycolysis?

To regenerate NAD+ for continued glycolysis

Why can't NADH+H+ directly traverse the mitochondrial inner membrane?

The membrane is impermeable to charged molecules

What is the relationship between ATP formation and substrate oxidation in the context of oxidative phosphorylation?

1 mole of the substrate oxidized forms 1.5 mol of ATP

What role does FADH2 play in oxidative phosphorylation?

Serves as a cofactor in some reactions involving ATP synthesis

How does the availability of ADP impact the respiration rate of mitochondria?

Higher ADP availability leads to higher respiration rates

Which specialized carrier is responsible for transporting ADP and Pi into mitochondria for ATP resynthesis?

Adenine nucleotide translocase

What is the main purpose of the Malate-Aspartate Shuttle system?

To transport electrons from the cytosol to the respiratory chain

Which enzyme is responsible for converting malate into oxaloacetate in the Malate-Aspartate Shuttle system?

Cytosolic malate dehydrogenase

What does the coupling of oxidation and phosphorylation imply in oxidative phosphorylation?

Oxidation cannot proceed without concomitant phosphorylation

Which protein is involved in importing ADP into the mitochondrial matrix while exporting ATP out?

Adenine nucleotide translocase

Where is the Glycerol 3-P Shuttle system mainly active?

Skeletal muscle

What is the role of dihydroxyacetone phosphate in the Glycerol 3-P Shuttle system?

To accept reducing equivalents from NADH+H

Which part of the mitochondria is responsible for reducing matrix NADs into NADH+Hs in the Malate-Aspartate Shuttle system?

Mitochondrial matrix

Which system allows for the continuity of anaerobic glycolysis by producing empty batteries (NAD+)?

Glycolysis in the cytosol

This quiz covers the electron flow and proton gradient in Complex IV of the respiratory chain, including the entry points of electron pairs from complexes I and II, as well as the role of coenzyme Q in fatty acid oxidation. Test your knowledge on these key concepts!

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