Retinoblastoma: The pRB Story Quiz

Oncogenes

Uncontrolled cellular growth

Development of its own blood supply

<p>When a primary tumour enters blood vessels and spreads around the body</p> Signup and view all the answers

<p>Activation of oncogenes or loss of function of tumour suppressor genes</p> Signup and view all the answers

<p>Their deactivation leads to genomic instability and cancer development</p> Signup and view all the answers

<p>Maintains telomeres in cells</p> Signup and view all the answers

<p>Discolouration in one of the child’s eyes</p> Signup and view all the answers

<p>40%</p> Signup and view all the answers

<p>Thermotherapy</p> Signup and view all the answers

<p>Chromosome loss</p> Signup and view all the answers

<p>Malignancy must be dominant</p> Signup and view all the answers

<p>Regulates Retinoblastoma</p> Signup and view all the answers

<p>~2 years old</p> Signup and view all the answers

<p>$P16$ gene</p> Signup and view all the answers

<p>Maintains telomeres in cells</p> Signup and view all the answers

<p>Maintains telomeres in cells</p> Signup and view all the answers

<p>Chromosome loss</p> Signup and view all the answers

<p>Gain of genetic information</p> Signup and view all the answers

<p>2 years old</p> Signup and view all the answers

<p>Spread of cancer to other parts of the body</p> Signup and view all the answers

<p>Cryotherapy</p> Signup and view all the answers

<p>Discolouration in the eyes</p> Signup and view all the answers

<p>Genomic instability</p> Signup and view all the answers

<p>Formation of blood vessels within a tumour</p> Signup and view all the answers

<p>Oncogenes can be activated, leading to genomic instability, while tumour suppressor genes can be deactivated, also leading to genomic instability</p> Signup and view all the answers

<p>It is the formation of a primary tumour's own blood supply</p> Signup and view all the answers

<p>It is when a primary tumour spreads to other parts of the body and forms secondary tumours</p> Signup and view all the answers

<p>Both activation of oncogenes and deactivation of tumour suppressor genes</p> Signup and view all the answers

<p>Deactivation of tumour suppressor genes leads to uncontrolled cellular growth, angiogenesis, and metastasis</p> Signup and view all the answers

<p>It leads to genomic instability and eventually contributes to cancer development</p> Signup and view all the answers