Questions and Answers
What is the composition of insulin?
Pro-insulin (A chain + Connecting [C] chain + B chain)
Which cells in the pancreas secrete somatostatin?
Delta cells (δ-cells)
What is the mechanism of insulin secretion in beta cells?
Glucose enters by GluT2, increases ATP, K+ channel blockade, affects K+ efflux, depolarization of cell membrane, Ca2+ influx, exocytosis of insulin
Which type of cells secrete glucagon in the pancreas?
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What maintains low basal levels of circulating insulin?
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