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Insulin Therapy in Pregnancy
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Insulin Therapy in Pregnancy

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Questions and Answers

What is the best insulin therapy pattern to achieve euglycemia in pregnancy?

  • No specific pattern needed
  • Physiologic basal bolus pattern (correct)
  • Random intermittent dosing
  • High-dose bolus only
  • Which basal insulin is the only one approved for use during pregnancy?

  • Detemir
  • Aspart
  • Neutral Protamine of Hagedorn (NPH) (correct)
  • Glargine
  • How much of the total daily dose (TDD) should be basal insulin in a physiologic administration of insulin during pregnancy?

  • 20-30%
  • 70-80%
  • 10-20%
  • 50-60% (correct)
  • What can cause hypoglycemia in pregnant women receiving intensive metabolic management?

    <p>Too much insulin</p> Signup and view all the answers

    What factor significantly increases the risk of preterm birth in women with preexisting diabetes?

    <p>Uncontrolled diabetes</p> Signup and view all the answers

    Why do symptoms of hypoglycemia in pregnant women receiving intensive metabolic management change over time?

    <p>Hormonal counter regulatory function becomes impaired</p> Signup and view all the answers

    What is the recommended pharmacologic therapy for women with type 2 diabetes who become pregnant?

    <p>Switch to insulin therapy</p> Signup and view all the answers

    When do insulin requirements peak throughout pregnancy for women with GDM?

    <p>Week 36 to term</p> Signup and view all the answers

    What is a common issue that women with pregestational diabetes, particularly type 1, are prone to during pregnancy?

    <p>Hypoglycemia</p> Signup and view all the answers

    What type of insulin is indicated when meals are inconsistent or delayed during pregnancy?

    <p>Regular insulin</p> Signup and view all the answers

    What is the recommended action when MNT and exercise do not achieve glycemic control in pregestational diabetes?

    <p>Initiate insulin therapy</p> Signup and view all the answers

    Why should the nurse review the increasing insulin requirements of pregnancy with a woman with diabetes?

    <p>To maintain consistent glucose levels</p> Signup and view all the answers

    What is the reason behind the maintenance of euglycemia in pregnancy?

    <p>Decreased insulin resistance</p> Signup and view all the answers

    Which fetal growth abnormalities are most frequently seen in women with pregestational or gestational diabetes?

    <p>Macrosomia and IUGR</p> Signup and view all the answers

    When should women with gestational diabetes mellitus (GDM) be screened for persistent diabetes postpartum?

    <p>6-12 weeks postpartum</p> Signup and view all the answers

    Which trimester is gestational diabetes mellitus (GDM) typically diagnosed?

    <p>Second trimester</p> Signup and view all the answers

    What is the recommended testing for high-risk pregnant women regarding gestational diabetes?

    <p>Oral Glucose Tolerance Test (OGTT) at the first prenatal visit</p> Signup and view all the answers

    What is the significant concern related to poorly controlled diabetes during pregnancy?

    <p>Risk of macrosomia in the infant</p> Signup and view all the answers

    Study Notes

    Insulin Therapy in Pregnancy

    • To achieve euglycemia in pregnancy, the best insulin therapy pattern involves a combination of basal, prandial, and correction insulin doses.
    • Detemir is the only basal insulin approved for use during pregnancy.

    Insulin Dosage in Pregnancy

    • In a physiologic administration of insulin during pregnancy, 30-40% of the total daily dose (TDD) should be basal insulin.

    Hypoglycemia in Pregnant Women

    • Causes of hypoglycemia in pregnant women receiving intensive metabolic management include increased insulin sensitivity, delayed meals, and inadequate carbohydrate intake.
    • Symptoms of hypoglycemia in pregnant women change over time due to hormonal fluctuations, which can lead to decreased counterregulatory responses.

    Risk Factors in Pregnancy

    • A significant factor that increases the risk of preterm birth in women with preexisting diabetes is hypertension.

    Pharmacologic Therapy in Pregnancy

    • For women with type 2 diabetes who become pregnant, the recommended pharmacologic therapy is a transition to insulin therapy.

    Insulin Requirements in Pregnancy

    • Insulin requirements peak during the 28th to 32nd weeks of gestation for women with gestational diabetes mellitus (GDM).

    Common Issues in Pregnancy

    • Women with pregestational diabetes, particularly type 1, are prone to diabetic ketoacidosis during pregnancy.

    Insulin Type in Pregnancy

    • When meals are inconsistent or delayed during pregnancy, a rapid-acting or short-acting insulin analog is indicated.

    Euglycemia Maintenance

    • The recommended action when medical nutrition therapy (MNT) and exercise do not achieve glycemic control in pregestational diabetes is to initiate insulin therapy.
    • The nurse should review the increasing insulin requirements of pregnancy with a woman with diabetes to prevent maternal and fetal complications.
    • The reason behind maintaining euglycemia in pregnancy is to prevent maternal and fetal complications, such as fetal growth abnormalities and congenital anomalies.

    Fetal Growth Abnormalities

    • Fetal growth abnormalities most frequently seen in women with pregestational or gestational diabetes include macrosomia and intrauterine growth restriction.

    Postpartum Screening

    • Women with gestational diabetes mellitus (GDM) should be screened for persistent diabetes postpartum at 6-12 weeks after delivery.

    Gestational Diabetes Diagnosis

    • Gestational diabetes mellitus (GDM) is typically diagnosed during the second trimester, between 24-28 weeks of gestation.

    Testing for Gestational Diabetes

    • The recommended testing for high-risk pregnant women regarding gestational diabetes is a 1-hour glucose challenge test.

    Concerns of Poorly Controlled Diabetes

    • The significant concern related to poorly controlled diabetes during pregnancy is an increased risk of maternal and fetal complications, including congenital anomalies, fetal growth abnormalities, and preterm birth.

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    Test your knowledge on insulin therapy in pregnancy with questions covering dosage, timing, basal bolus pattern, and types of insulin recommended during pregnancy.

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