Cirrhosis Complications Overview

What is the normal total serum bilirubin level range?

0.3-1.2 mg/dl

What is an early sign of Wilson's disease?

Decreased ceruloplasmin levels

What causes Dubin-Johnson syndrome?

Deficiency in MRP2

What is the primary function of ATP7B in the liver?

Exocytose copper into bile canaliculi Signup and view all the answers

Which condition can lead to dark urine and dark liver?

Obstructive jaundice Signup and view all the answers

What is a common cause of increase in both unconjugated and conjugated bilirubin in the blood?

Viral Hepatitis Signup and view all the answers

Which tissue does free copper primarily accumulate in Wilson's disease?

Liver Signup and view all the answers

What complications can arise from obstructive jaundice?

Pruritis, Steatorrhea Signup and view all the answers

Which symptom is NOT associated with hepatic encephalopathy?

Jaundice Signup and view all the answers

What can trigger renal vasoconstriction leading to hepatorenal failure in cirrhosis?

High portal vein pressure Signup and view all the answers

How does phototherapy help in treating physiologic jaundice of newborns?

Converting bilirubin to a more soluble form Signup and view all the answers

What is the consequence of low liver function in hepatic encephalopathy?

Accumulation of toxins in the brain Signup and view all the answers

In cirrhosis, what happens to estrogen metabolism with liver damage?

Estrogen production increases Signup and view all the answers

What causes the yellow discoloration of skin and eyes in jaundice?

Retention of bilirubin Signup and view all the answers

In compensated cirrhosis, what is the characteristic of the liver?

Presence of small amount of scarring and fibrosis Signup and view all the answers

What is a common symptom of decompensated cirrhosis?

All listed complications and symptoms Signup and view all the answers

How does hepatorenal failure progress from changes in portal flow?

Renal vasoconstriction triggered Signup and view all the answers

'Asterixis', characterized by tremoring or jerky hands when outstretched, is a symptom of which complication?

Hepatic encephalopathy Signup and view all the answers

'Palmar erythema', a condition seen in cirrhosis, is a result of what physiological process?

'CB' secretion by hepatocytes Signup and view all the answers

What is the main cause of liver cirrhosis as discussed in the text?

Excessive alcohol consumption Signup and view all the answers

What are considered the most common risk factors for liver cirrhosis based on the text?

Excessive alcohol consumption and fatty liver (NASH) Signup and view all the answers

What does the presence of regenerative nodules, fibrotic tissue, and collagen indicate in liver pathology?

Formation of scar tissue in the liver Signup and view all the answers

How does liver cirrhosis contribute to the development of jaundice?

By impairing bilirubin excretion Signup and view all the answers

What role do hepatic stellate cells (HSC) play in the pathogenesis of liver fibrosis?

Secreting paracrine factors that stimulate HSC proliferation Signup and view all the answers

In liver cirrhosis, how does the accumulation of fibrotic tissue affect blood flow in the liver?

Compresses central veins and sinusoids Signup and view all the answers

Which factor contributes to activating hepatic stellate cells (HSC) in injured liver tissues?

Paracrine factors from sinusoidal endothelial cells and hepatocytes Signup and view all the answers

What distinguishes liver cirrhosis from end-stage liver disease?

Irreversible fibrosis and scarring Signup and view all the answers

What happens to hepatic stellate cells (HSC) when they are activated?

They lose vitamin A and secrete TGF-β1 Signup and view all the answers

How does chronic inflammation in liver cirrhosis contribute to scar tissue formation?

By enhancing natural wound healing processes Signup and view all the answers

Cirrhosis Complications Overview

Questions and Answers

What is the normal total serum bilirubin level range?

What is an early sign of Wilson's disease?

What causes Dubin-Johnson syndrome?

What is the primary function of ATP7B in the liver?

Which condition can lead to dark urine and dark liver?

What is a common cause of increase in both unconjugated and conjugated bilirubin in the blood?

Which tissue does free copper primarily accumulate in Wilson's disease?

What complications can arise from obstructive jaundice?

Which symptom is NOT associated with hepatic encephalopathy?

What can trigger renal vasoconstriction leading to hepatorenal failure in cirrhosis?

How does phototherapy help in treating physiologic jaundice of newborns?

What is the consequence of low liver function in hepatic encephalopathy?

In cirrhosis, what happens to estrogen metabolism with liver damage?

What causes the yellow discoloration of skin and eyes in jaundice?

In compensated cirrhosis, what is the characteristic of the liver?

What is a common symptom of decompensated cirrhosis?

How does hepatorenal failure progress from changes in portal flow?

'Asterixis', characterized by tremoring or jerky hands when outstretched, is a symptom of which complication?

'Palmar erythema', a condition seen in cirrhosis, is a result of what physiological process?

What is the main cause of liver cirrhosis as discussed in the text?

What are considered the most common risk factors for liver cirrhosis based on the text?

What does the presence of regenerative nodules, fibrotic tissue, and collagen indicate in liver pathology?

How does liver cirrhosis contribute to the development of jaundice?

What role do hepatic stellate cells (HSC) play in the pathogenesis of liver fibrosis?

In liver cirrhosis, how does the accumulation of fibrotic tissue affect blood flow in the liver?

Which factor contributes to activating hepatic stellate cells (HSC) in injured liver tissues?

What distinguishes liver cirrhosis from end-stage liver disease?

What happens to hepatic stellate cells (HSC) when they are activated?

How does chronic inflammation in liver cirrhosis contribute to scar tissue formation?

More Quizzes Like This

Liver Cirrhosis & Its Complications - Definition and Causes

Portal Hypertension and Bleeding Varices Learning Objectives

Cirrhosis Symptoms and Complications

Cirrhosis Complications

Upgrade to continue

Cirrhosis Complications Overview

Questions and Answers

What is the normal total serum bilirubin level range?

What is an early sign of Wilson's disease?

What causes Dubin-Johnson syndrome?

What is the primary function of ATP7B in the liver?

Which condition can lead to dark urine and dark liver?

What is a common cause of increase in both unconjugated and conjugated bilirubin in the blood?

Which tissue does free copper primarily accumulate in Wilson's disease?

What complications can arise from obstructive jaundice?

Which symptom is NOT associated with hepatic encephalopathy?

What can trigger renal vasoconstriction leading to hepatorenal failure in cirrhosis?

How does phototherapy help in treating physiologic jaundice of newborns?

What is the consequence of low liver function in hepatic encephalopathy?

In cirrhosis, what happens to estrogen metabolism with liver damage?

What causes the yellow discoloration of skin and eyes in jaundice?

In compensated cirrhosis, what is the characteristic of the liver?

What is a common symptom of decompensated cirrhosis?

How does hepatorenal failure progress from changes in portal flow?

'Asterixis', characterized by tremoring or jerky hands when outstretched, is a symptom of which complication?

'Palmar erythema', a condition seen in cirrhosis, is a result of what physiological process?

What is the main cause of liver cirrhosis as discussed in the text?

What are considered the most common risk factors for liver cirrhosis based on the text?

What does the presence of regenerative nodules, fibrotic tissue, and collagen indicate in liver pathology?

How does liver cirrhosis contribute to the development of jaundice?

What role do hepatic stellate cells (HSC) play in the pathogenesis of liver fibrosis?

In liver cirrhosis, how does the accumulation of fibrotic tissue affect blood flow in the liver?

Which factor contributes to activating hepatic stellate cells (HSC) in injured liver tissues?

What distinguishes liver cirrhosis from end-stage liver disease?

What happens to hepatic stellate cells (HSC) when they are activated?

How does chronic inflammation in liver cirrhosis contribute to scar tissue formation?

More Quizzes Like This

Liver Cirrhosis &amp; Its Complications - Definition and Causes

Portal Hypertension and Bleeding Varices Learning Objectives

Cirrhosis Symptoms and Complications

Cirrhosis Complications

Liver Cirrhosis & Its Complications - Definition and Causes