Podcast
Questions and Answers
What is the primary mechanism of action of beta blockers in the management of portal hypertension?
What is the primary mechanism of action of beta blockers in the management of portal hypertension?
- Enhance renal blood flow
- Increase arterial vasodilation
- Decrease cardiac output and splanchnic blood flow (correct)
- Promote sodium and water excretion
In portal hypertension, what effect does liver fibrosis due to cirrhosis have on blood flow in the portal vein?
In portal hypertension, what effect does liver fibrosis due to cirrhosis have on blood flow in the portal vein?
- Increases blood flow
- No effect on blood flow
- Decreases blood flow (correct)
- Causes arterial vasodilation
How does splanchnic vasodilation contribute to the pathophysiology of portal hypertension?
How does splanchnic vasodilation contribute to the pathophysiology of portal hypertension?
- Promotes sodium retention
- Causes arterial vasoconstriction
- Leads to increased portal blood flow (correct)
- Reduces cardiac output
What is the typical pressure gradient indicative of portal hypertension compared to normal pressure gradient?
What is the typical pressure gradient indicative of portal hypertension compared to normal pressure gradient?
How do beta blockers affect the splanchnic system to reduce portal blood flow?
How do beta blockers affect the splanchnic system to reduce portal blood flow?
Which of the following is NOT a complication associated with portal hypertension?
Which of the following is NOT a complication associated with portal hypertension?
What is the primary prophylaxis treatment recommended for patients with varices at high risk for bleeding?
What is the primary prophylaxis treatment recommended for patients with varices at high risk for bleeding?
In the treatment of bleeding varices, which drug is preferred due to its ability to slow or stop bleeding by various mechanisms?
In the treatment of bleeding varices, which drug is preferred due to its ability to slow or stop bleeding by various mechanisms?
What is the preferred endoscopic treatment for bleeding varices due to its lower complication rate compared to other procedures?
What is the preferred endoscopic treatment for bleeding varices due to its lower complication rate compared to other procedures?
Which of the following drugs is used in combination with vasopressin in the treatment of bleeding varices to prevent splanchnic vasodilation?
Which of the following drugs is used in combination with vasopressin in the treatment of bleeding varices to prevent splanchnic vasodilation?
What is the gold standard for diagnosing varices?
What is the gold standard for diagnosing varices?
Which grade of varices is characterized by large diameter (>5mm)?
Which grade of varices is characterized by large diameter (>5mm)?
What is the maximum duration for which vasopressin should be infused in the treatment of bleeding varices?
What is the maximum duration for which vasopressin should be infused in the treatment of bleeding varices?
Which drug class is cautioned against due to its potential increase in the risk of hepatorenal syndrome in cirrhosis patients?
Which drug class is cautioned against due to its potential increase in the risk of hepatorenal syndrome in cirrhosis patients?
What is the primary screening method recommended for all cirrhotic patients to detect varices?
What is the primary screening method recommended for all cirrhotic patients to detect varices?
Which drug is used for secondary prophylaxis in patients with varices and should be titrated based on patient-specific factors?
Which drug is used for secondary prophylaxis in patients with varices and should be titrated based on patient-specific factors?
