Bleeding Disorders Integrated Hematology/Oncology Module

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21 Questions

Hemophilia A is characterized by deficiency of factor IX.

False

Clinical manifestation of anti-phospholipid syndrome may include both transient ischemic stroke and blood in the urine.

False

Plasmapheresis is a potential treatment option for controlling progressive thromboembolism in patients with Catastrophic Antiphospholipid Syndrome (CAPS).

True

Pharmacists do not play a significant role in managing blood disorders.

False

Hemophilia B is characterized by deficiency of factor IX.

True

What is the direct cost of care related to hemophilia A in 2008?

More than $140,000

In which type of bleeding disorder is there a congenital deficiency in a plasma coagulation protein?

Hemophilia A

What is the approximate number of males in the US affected by hemophilia A?

30,000

Which organization has published 2021 guidelines on the management of von Willebrand disease?

ASH

What is a potential complication for patients with hemophilia A in terms of healthcare costs?

Development of inhibitors

What is the recommended treatment for antiphospholipid syndrome in adults according to EULAR?

Anticoagulation therapy

What is the inheritance pattern of Hemophilia B?

X-linked recessive

Which factor is deficient in Hemophilia A?

Factor VIII

What percentage of all patients with hemophilia have Hemophilia A?

80-85%

In terms of circulating factor levels, which category of hemophilia is defined as 'severe'?

1 – 5% circulating factor

Which of the following is a clinical manifestation of anti-phospholipid syndrome in a newly diagnosed patient?

Transient ischemic stroke

What is the primary treatment for controlling progressive thromboembolism in patients with Catastrophic Antiphospholipid Syndrome (CAPS)?

Plasmapheresis

What role do pharmacists play in managing blood disorders?

Provide treatment recommendations and manage drug interactions

Which blood disorder may require acute management and prophylaxis due to potential complications?

Hemophilia

How are DOACs (Direct Oral Anticoagulants) used in the context of typical VTE?

For prophylaxis only

What are the potential treatments for Catastrophic Antiphospholipid Syndrome (CAPS)?

All of the above

Learn about bleeding disorders such as hemophilia A and hemophilia B, and treatment options for antiphospholipid syndrome. This module provides detailed slides and objectives on differentiating between bleeding disorders, developing treatment plans, and understanding various treatment options.

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