7 Questions
What type of gene segments are separated by introns in the germline of inherited antigen receptor gene loci?
Coding segments
How is combinatorial diversity achieved in the immune system?
By different rearrangement combinations of V, D, and J gene segments
Where do B cells undergo VDJ recombination?
Bone marrow
Which gene arrangement correctly describes the Kappa light chain immunoglobulin genes?
Light chain gene expression on chromosome 2 with VJ segments and one constant domain
What is a correct statement about introns in immunoglobulin genes?
Introns are not expressed and are removed in mature mRNA
What distinguishes Natural Killer T-cells (NK-T cells) from regular T cells?
Recognize lipid antigens displayed by MHC-like molecules known as CD1
Which property is unique to gamma delta T cells?
Have broad specificity similar to innate immune cells
Test your knowledge on the gene arrangement of Kappa light chain immunoglobulin genes and introns in immunoglobulin genes. Learn about the structure of light chain gene proteins and the role of introns in antigen receptor gene loci.
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