Podcast
Questions and Answers
What is required for a T cell to be activated?
What is required for a T cell to be activated?
- Binding of a T cell receptor to a foreign antigen
- Binding of a T cell receptor to a histocompatibility antigen
- Binding of a T cell receptor to both a foreign antigen and a histocompatibility antigen (correct)
- Binding of a T cell receptor to a macrophage
What happens to a foreign body, such as a virus, after it is ingested by a macrophage?
What happens to a foreign body, such as a virus, after it is ingested by a macrophage?
- It is immediately destroyed by the macrophage
- It is partly digested and displayed on the macrophage's surface (correct)
- It remains intact and is not affected by the macrophage
- It is fully digested by the macrophage
What is the result of a T cell binding to both a histocompatibility protein and a foreign antigen?
What is the result of a T cell binding to both a histocompatibility protein and a foreign antigen?
- The T cell is inactivated
- The T cell is activated and secretes substances that stimulate the immune system
- The T cell is activated and secretes substances that destroy the antigen-containing cell (correct)
- The T cell is activated and secrete substances that inhibit the immune system
Why are the MHC genes considered highly variable?
Why are the MHC genes considered highly variable?
What is the likelihood that two people (excluding identical twins) have the same set of histocompatibility antigens?
What is the likelihood that two people (excluding identical twins) have the same set of histocompatibility antigens?
What is the purpose of the histocompatibility antigen on the surface of a macrophage?
What is the purpose of the histocompatibility antigen on the surface of a macrophage?
What is the outcome when a T cell binds to both a histocompatibility protein and a foreign antigen?
What is the outcome when a T cell binds to both a histocompatibility protein and a foreign antigen?
How do macrophages display antigens from a foreign body?
How do macrophages display antigens from a foreign body?
What is the significance of the high variability of MHC genes?
What is the significance of the high variability of MHC genes?
What is the role of T cells in the immune response?
What is the role of T cells in the immune response?
What is the function of MHC loci in the immune response?
What is the function of MHC loci in the immune response?
Why are identical twins likely to have the same set of histocompatibility antigens?
Why are identical twins likely to have the same set of histocompatibility antigens?
What is the purpose of the T-cell receptor?
What is the purpose of the T-cell receptor?
What happens to a foreign body after it is ingested by a macrophage?
What happens to a foreign body after it is ingested by a macrophage?
What is the result of the high variability of MHC genes in the context of organ transplantation?
What is the result of the high variability of MHC genes in the context of organ transplantation?