23 Questions
What is the site of creatine synthesis?
Liver and kidney tissue
What is the function of creatine phosphate?
Rapid release of energy for intense muscular contraction
What is the amount of phosphocreatine in the body proportional to?
Muscle mass
What is the byproduct of creatine and phosphocreatine cyclization?
Creatinine
What happens to the creatinine content of the urine when muscle mass decreases?
It falls
What is the enzyme involved in the reversible phosphorylation of creatine?
Creatine kinase
What are the amino acids involved in creatine synthesis?
Glycine and arginine
What do dopamine, norepinephrine, and epinephrine have in common?
They are synthesized from tyrosine
What is the function of epinephrine in the body?
Triggering the fight-or-flight response
What is the role of dopamine in the nervous system?
Sending signals throughout the nervous system
What is the source of tyrosine for catecholamine synthesis?
Dietary proteins
What is the primary function of serotonin in the brain?
Modulation of pain perception
Where is most of the body's serotonin supply found?
Digestive tract
What is the function of noradrenaline in the body?
To help respond to stress by increasing heart rate and blood pressure
What is the precursor to serotonin synthesis?
Tryptophan
What is the rate-limiting step in the synthesis of catecholamines?
Tyrosine Hydroxylation
What is the treatment for Parkinson's disease?
Administration of L-DOPA (levodopa)
What is the function of histamine in the body?
Powerful vasodilator
What is the function of catecholamines outside the nervous system?
To generate body heat and stimulate the breakdown of triglycerides
What is the pigment found in several tissues?
Melanin
What is the enzyme responsible for the degradation of catecholamines?
Monoamine oxidase (MAO) and catechol-O-methyl-transferase (COMT)
What is the enzyme involved in serotonin degradation?
Monoamine oxidase (MAO)
What is the reaction required for the synthesis of epinephrine?
N-methylation of norepinephrine
This quiz covers the overview of nitrogen-containing compounds, including their precursors, functions, and synthesis. It also delves into the specifics of creatine synthesis, including its site, amino acids, and resultant compounds. Test your knowledge of these important biological molecules!
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