Bile Acid Sequestrants and their Effects Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a common complication of heart failure that makes digoxin particularly beneficial for patients with concurrent atrial fibrillation?

  • Visual disturbances
  • Ventricular arrhythmias (correct)
  • Sinus bradycardia
  • Hypokalemia

What is the recommended therapeutic serum concentration range for digoxin in patients with arrhythmias?

  • 1.5-2.5 ng/mL (correct)
  • 0.8-1.2 ng/mL
  • 0.5-0.8 ng/mL
  • 2-3 ng/mL

Which of the following is a common noncardiac adverse effect associated with digoxin?

  • Anorexia and nausea (correct)
  • Atrial arrhythmias
  • Hypercalcemia
  • Ventricular arrhythmias

What is the mechanism of action of milrinone in the treatment of heart failure?

<p>Inhibits phosphodiesterase (D)</p> Signup and view all the answers

When should Digibind or DigiFab be considered in relation to digoxin toxicity?

<p>If signs and symptoms of cardiovascular toxicity are present (B)</p> Signup and view all the answers

Why should calcium-channel blockers be avoided in the treatment of congestive heart failure?

<p>Concerns over safety and lack of efficacy evidence (A)</p> Signup and view all the answers

Which type of drug can relieve pruritus caused by the accumulation of bile acids in patients with biliary stasis?

<p>Bile Acid Sequestrants (C)</p> Signup and view all the answers

What is the mechanism of action of Ezetimibe (Zetia®)?

<p>Acts on the brush border of intestinal epithelial cells to inhibit cholesterol absorption (C)</p> Signup and view all the answers

Which drug combination is contraindicated in patients with active liver disease or unexplained persistent elevations in serum transaminases?

<p>Ezetimibe and Statins (D)</p> Signup and view all the answers

Which drug is indicated for type 2 diabetes due to its glucose-lowering effects?

<p>Colesevelam (A)</p> Signup and view all the answers

Which condition involves atherosclerotic lesions forming and occluding the vessels?

<p>Coronary artery disease (D)</p> Signup and view all the answers

Which drug category leads to a reduction in hepatic production of triglycerides, thus decreasing the production of VLDL?

<p>Fish oil supplements (B)</p> Signup and view all the answers

What is the primary effect of β-Adrenergic Blockers in the management of angina?

<p>Decrease oxygen demand of the myocardium by blocking β receptors (A)</p> Signup and view all the answers

Which drug is recommended as initial antianginal therapy in all patients unless contraindicated?

<p>β-blockers (A)</p> Signup and view all the answers

What is the primary adverse effect commonly associated with Nitrates?

<p>Headache (A)</p> Signup and view all the answers

Which drug category selectively inhibits the absorption of cholesterol from diet and biliary sources?

<p>Ezetimibe (C)</p> Signup and view all the answers

Which of the following statements about sotalol is correct?

<p>It is a Class III antiarrhythmic agent with beta-blocker activity. (B)</p> Signup and view all the answers

Which of the following is a common adverse effect of amiodarone?

<p>Pulmonary fibrosis or interstitial pneumonitis (D)</p> Signup and view all the answers

What is the mechanism of action of Class III antiarrhythmic agents?

<p>Inhibit potassium channels and delay repolarization. (C)</p> Signup and view all the answers

Which of the following statements about dofetilide is true?

<p>It is metabolized extensively in the liver. (C)</p> Signup and view all the answers

What is a characteristic pharmacokinetic property of amiodarone?

<p>Long half-life, ranging from 26 to 107 days. (B)</p> Signup and view all the answers

Which of the following statements about Class III antiarrhythmic agents is true?

<p>They are primarily used for the treatment of atrial fibrillation. (B)</p> Signup and view all the answers

Which type of drug is specifically contraindicated in patients with asthma, diabetes, and peripheral vascular disease?

<p>β-Blocker (B)</p> Signup and view all the answers

How do α1-Receptor Blockers like Doxazosin work in the treatment of BPH?

<p>By blocking vascular alpha adrenoreceptors (D)</p> Signup and view all the answers

What is the main action of Peripheral Vasodilators like Hydralazine and Minoxidil?

<p>Reducing peripheral vascular resistance (C)</p> Signup and view all the answers

Which medication is commonly used for hypertensive emergencies but can lead to adverse effects like cyanide toxicity?

<p>Sodium Nitroprusside (B)</p> Signup and view all the answers

What is the main characterizing feature of Systolic Heart Failure?

<p>Inability to pump enough blood out (D)</p> Signup and view all the answers

Which class of drugs is known to improve outcomes in heart failure by reducing vasoconstriction and sodium retention?

<p>Angiotensin Converting Enzyme Inhibitors (ACEIs) (A)</p> Signup and view all the answers

What is the primary mechanism of action of Angiotensin II Receptor Blockers (ARBs) like Losartan?

<p>Lower angiotensin II levels (B)</p> Signup and view all the answers

What is a common side effect associated with Aldosterone Antagonists like Spironolactone?

<p>Gynecomastia (B)</p> Signup and view all the answers

What is a potential adverse reaction associated with β-Blockers?

<p>Bronchospasm (B)</p> Signup and view all the answers

What is the main recommended use of Digoxin in patients with heart failure symptoms?

<p>Increasing intracellular Ca levels (D)</p> Signup and view all the answers

Which of the following statements about quinidine is correct?

<p>All of the above. (D)</p> Signup and view all the answers

Which of the following statements about procainamide is incorrect?

<p>N-acetyl-procainamide (NAPA) is an inactive metabolite. (A)</p> Signup and view all the answers

Which of the following is a Class IB antiarrhythmic agent?

<p>Lidocaine (A)</p> Signup and view all the answers

What is the mechanism of action of Class IB antiarrhythmic agents?

<p>Inhibit sodium channels (fast on-off) and enhance potassium current. (C)</p> Signup and view all the answers

Which of the following side effects is associated with tocainide, a Class IB antiarrhythmic agent?

<p>Agranulocytosis and thrombocytopenia (C)</p> Signup and view all the answers

Which of the following statements about lidocaine, a Class IB antiarrhythmic agent, is correct?

<p>All of the above. (D)</p> Signup and view all the answers

Which of the following is a Class IC antiarrhythmic agent?

<p>Flecainide (D)</p> Signup and view all the answers

What is the mechanism of action of Class IC antiarrhythmic agents?

<p>Inhibit sodium channels (slow on-off) and decrease automaticity. (B)</p> Signup and view all the answers

Which of the following side effects is associated with propafenone, a Class IC antiarrhythmic agent?

<p>Bronchospasm and lupus-like syndrome (B)</p> Signup and view all the answers

Which of the following statements about beta-blockers (Class II antiarrhythmic agents) is incorrect?

<p>They increase conduction velocity and decrease refractoriness. (B)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Use Quizgecko on...
Browser
Browser