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Cholestyramine Overview

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Questions and Answers

What is the drug classification of cholestyramine?

bile acid sequestrate

What is the action of cholestyramine?

Sequestrate bind the bile acid with cholesterol, thus sequestering it away from circulation and eliminating cholesterol through the feces.

What are the indications and uses of cholestyramine?

antihyperlipidemic

What are the side effects of cholestyramine?

GI effects: because this is not absorbed by the small intestine into circulation; NO SYSTEMIC EFFECTS Signup and view all the answers

What are the nursing considerations for cholestyramine?

Mix it with lots of fluid to avoid esophageal irritation. Monitor AST and ALP. Can bind to digoxin, penicillins, thyroid hormones, and thiazide; DO NOT take them at the same time. Signup and view all the answers

What patient teaching is advised for cholestyramine?

To prevent constipation: increase fluids, fibers, and exercise; max effect is 3 weeks. Signup and view all the answers

Study Notes

Drug Classification

Classified as a bile acid sequestrate.

Mechanism of Action

Binds bile acids containing cholesterol, preventing their reabsorption.
Cholesterol is eliminated from the body through feces.

Indications and Uses

Primarily used as an antihyperlipidemic agent to lower cholesterol levels.

Side Effects

Gastrointestinal (GI) effects are common due to lack of systemic absorption.
No systemic effects since it is not absorbed into circulation.

Nursing Considerations

Mix cholestyramine with ample fluids to minimize risk of esophageal irritation.
Regularly monitor liver enzymes: AST and ALP levels.
Can interfere with the absorption of other medications such as digoxin, penicillins, thyroid hormones, and thiazides; do not take concurrently.

Patient Teaching

Advise patients to prevent constipation by increasing fluid intake, dietary fiber, and regular exercise.
Inform that maximum therapeutic effect typically takes up to three weeks to manifest.

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Description

This quiz provides essential flashcard information about cholestyramine, including its drug classification, mechanism of action, uses, and side effects. Perfect for those studying pharmacology or healthcare professionals looking to refresh their knowledge.