Questions and Answers
What is the drug classification of cholestyramine?
bile acid sequestrate
What is the action of cholestyramine?
Sequestrate bind the bile acid with cholesterol, thus sequestering it away from circulation and eliminating cholesterol through the feces.
What are the indications and uses of cholestyramine?
antihyperlipidemic
What are the side effects of cholestyramine?
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What are the nursing considerations for cholestyramine?
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What patient teaching is advised for cholestyramine?
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Study Notes
Drug Classification
- Classified as a bile acid sequestrate.
Mechanism of Action
- Binds bile acids containing cholesterol, preventing their reabsorption.
- Cholesterol is eliminated from the body through feces.
Indications and Uses
- Primarily used as an antihyperlipidemic agent to lower cholesterol levels.
Side Effects
- Gastrointestinal (GI) effects are common due to lack of systemic absorption.
- No systemic effects since it is not absorbed into circulation.
Nursing Considerations
- Mix cholestyramine with ample fluids to minimize risk of esophageal irritation.
- Regularly monitor liver enzymes: AST and ALP levels.
- Can interfere with the absorption of other medications such as digoxin, penicillins, thyroid hormones, and thiazides; do not take concurrently.
Patient Teaching
- Advise patients to prevent constipation by increasing fluid intake, dietary fiber, and regular exercise.
- Inform that maximum therapeutic effect typically takes up to three weeks to manifest.
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Description
This quiz provides essential flashcard information about cholestyramine, including its drug classification, mechanism of action, uses, and side effects. Perfect for those studying pharmacology or healthcare professionals looking to refresh their knowledge.
