Podcast
Questions and Answers
What is the fate of chylomicron remnants in the liver?
What is the fate of chylomicron remnants in the liver?
- They are converted into LDL
- They are transported back into the bloodstream
- They are further metabolized into VLDL
- They are stored, oxidized to bile acids, or secreted in the bile (correct)
What is the role of lipoprotein lipase in triglyceride regulation?
What is the role of lipoprotein lipase in triglyceride regulation?
- It oxidizes cholesterol to bile acids
- It hydrolyzes triglycerides in chylomicrons and VLDL into FFA (correct)
- It converts LDL into HDL
- It assembles cholesterol and triglycerides into VLDL
What is the primary function of inhibitors of intestinal cholesterol absorption?
What is the primary function of inhibitors of intestinal cholesterol absorption?
- To reduce cholesterol absorption in the gut (correct)
- To increase triglyceride synthesis
- To oxidize cholesterol to bile acids
- To increase VLDL production
What is the primary mechanism of action of cholestyramine and colestipol?
What is the primary mechanism of action of cholestyramine and colestipol?
What happens to cholesterol in LDL?
What happens to cholesterol in LDL?
What is the therapeutic use of nicotinic acid?
What is the therapeutic use of nicotinic acid?
What is the primary goal of non-drug therapy for hyperlipidemia?
What is the primary goal of non-drug therapy for hyperlipidemia?
What is the effect of HMG-CoA reductase inhibitors on cholesterol synthesis?
What is the effect of HMG-CoA reductase inhibitors on cholesterol synthesis?
What is the effect of fibric acid derivatives on peripheral catabolism of VLDL and chylomicrons?
What is the effect of fibric acid derivatives on peripheral catabolism of VLDL and chylomicrons?
What is the class of drugs that include Atorvastatin, Simvastatin, and Lovastatin?
What is the class of drugs that include Atorvastatin, Simvastatin, and Lovastatin?
What is the potential adverse effect of combining statins with fibrates?
What is the potential adverse effect of combining statins with fibrates?
What is the effect of cholestyramine and colestipol on the absorption of fat-soluble vitamins?
What is the effect of cholestyramine and colestipol on the absorption of fat-soluble vitamins?
What is the primary function of high density lipoproteins (HDLs) in the blood?
What is the primary function of high density lipoproteins (HDLs) in the blood?
What is the main component of chylomicrons?
What is the main component of chylomicrons?
What is the purpose of apolipoproteins in lipid transport?
What is the purpose of apolipoproteins in lipid transport?
What is the term for an excess of fatty substances called lipids in the blood?
What is the term for an excess of fatty substances called lipids in the blood?
What is the transitional form between chylomicrons and low-density lipoproteins?
What is the transitional form between chylomicrons and low-density lipoproteins?
What is the site of production of chylomicrons?
What is the site of production of chylomicrons?
