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Dr. Susan S. Montemayor
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This document is a collection of questions and answers related to the preparation of crude drugs used in the commercial market. It also covers the natural relationship among plants and animals, and various definitions in pharmaceutical chemistry. Important details are included on the evaluation of drugs and their usage in modern medicine.
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CEU SOP IPS-1 For Pharmacognosy and Plant Chemistry Prepared by Dr. Susan S. Montemayor 1. The following are general steps in the preparation of the...
CEU SOP IPS-1 For Pharmacognosy and Plant Chemistry Prepared by Dr. Susan S. Montemayor 1. The following are general steps in the preparation of the crude drug for commercial market, except: A. Harvesting B. Garbling C. Storage and drying D. None of the choices 2. The process of removing sufficient moisture to ensure good keeping qualities: A. Harvesting B. Drying C. Collection D. Garbling E. None of the choices 3. This refers to the evaluation by means of the organs of sense and includes macroscopic appearance of drug: A. Microscopic C. Macroscopic E. None of the choices B. Organoleptic D. Both A, B & C 4. Drugs classified according to the natural relationship among plants and animals: A. Zoological arrangement C. Morphological classification B. Chemical classification D. Taxonomic classification 5. He defined Pharmacognosy as an applied science that deals with the biologic , biochemical and economic features of natural drugs and their constituents: A. Seydler B. Fluckiger C. Tyler D. Scheele 6. Plant acid isolated in crystal form from lemon by Scheele in 1784: A. Tartaric acid B. Lactic acid C. Citric acid D. Nitric acid 7. The technical term for solvent used during extraction: A. Menstrual B. Menstruum C. Extract D. Marc 8. A Greek physician-pharmaco-botanist in 78 AD, the author of De Materia Medica: A. Hippocrates B. Theophrastus C. Galen D. Dioscorides 9. The study of the use of chemical agents which are more selectively toxic to the invading organism then to host is known as: A. Physiology B. Chemotheraphy C. Immunology D. Pharmacology 10. The medicinal use of plant extracts: A. Medical ethnobotany B. Ethnopharmacology C. Phytotherapy D. Phytochemistry 11. The step in the preparation of crude drug which consists of the removal of the extraneous matter prior to packaging: A. Selection B. Drying C. Collection D. Garbling 12. The new name of the family Gramineae: A. Poaceae B. Asteraceae C. Caesalpinaceae D. Arecaceae 13. The new name of the family Palmae: A. Poaceae B. Asteraceae C. Caesalpinaceae D. Arecaceae 14. Plant part collected when vegetative processes have ceased: A. Roots and rhizome B. Flowers C. Leaves D. Seeds 15. The study of chemicals derived from plants: A. Medical ethnobotany B. Ethnopharmacology C. Phytotherapy D. Phytochemistry 16. The region in which the plant or animal yielding the drug grows: A. Habitat B. Indigenous C. Naturalized D. Cultivated 17. Which ancient civilization wrote the Ebers Papyrus which contained medicinal uses of plant and animals? A. Greeks B. Egyptians C. Sumerian D. Babylonians 18. Which of the following evaluation is best use in the determination of adulterants in powdered drugs? A. Chemical B. Physical C. Biological D. Microscopic 19. The originator of the formula for cold cream: A. Hippocrates B. Theophrastus C. Galen D. Dioscorides 20. Animal starch is also known as: A.Glycogen B. Chitin C. Chitosan D. None of the choices 21. These metabolites are considered waste products but possessing therapeutic effect: A. Primary B. Secondary C. Both A & B D. None of them 22. The following are primary metabolites, except: A. Carbohydrate B. Protein C. Fats D. Saponin 23. Pollen, mold spores, animal dander, and poison ivy are examples of: A. Allergen B. Antibiotics C. Vitamins D. Hormones 24. Derivatives of Cyclopentanophenanthrene such as estrogens, androgens, adrenal cortex, hormones, cholesterol, aglycones and ergosterol: A. Antibiotics B. Steroids C. Alkaloids D. Glycosides 25. A group of complex phenolic compounds capable of combining with proteins: A. Resin B. Alkaloids C. Tannins D. Glycosides 26. The substances are active principles secreted by the endocrine glands like glucagon, insulin, oxytocin and vasopressin: A. Resin B. Protein C. Lipids D. Hormones 27. A process in which a comminuted drug is extracted of its soluble constituents by the slow passage of suitable solvent through a column of the drug: A. Maceration B. Percolation C. Digestion D. Decoction 28. Pharmacognosy embraces _____: A. Cultivation, collection and preparation of herbal plants C. Both A & B B. Commerce, identification and preservation of drugs D. None of them 29. Stages in the preparation of drugs for the commercial market involves: A. Handwashing D. Both A, B, & C B. Garbling and drying E. None of the choices C. Packaging, storage & preservation 30. In pharmacognosy, drugs maybe classified based on the following, except: A. Their price in the market C. Their chemical constituents B. Their morphology D. Their therapeutic application 31. All are drugs consisting of cremocarp fruits, except: A. Anise B. Fennel C. Caraway D. Cassia 32. Purpose/s of drying: I. Ensure good keeping qualities II. Facilitate milling and grinding III. Permit the action of enzymes and bacteria IV. It fixes the constituents A. I & II B. III only C. Both I, II & III D. Both I, II, & IV 33. It refers to a method off obtaining a constituents of a drug by heating the drug to vaporize its chief constituent to a gaseous state and condensing the vapor back to a solid form: A. Sublimation B. Crystallography C. Microscopy D. Chromatography 34. Refractive index is used to determine the purity and therapeutic value of: A. Volatile oil B. Alkaloids C. Resin D. Tannins 35. The following factors influence secondary constituents of plant drugs, except: A. Heredity B. Ontogeny C. Commerce D. Environment 36. _____ is a process based on the distribution of a mixture between 2 phases: A. Painting B. Electrolysis C. Filtration D. Chromatography 37. This is the solvent most commonly used for the extraction of chlorophyll from leaves: A. Acetone B. Ethanol C. Dimethylformamide D. Dimethylsulfoxide 38. The science of the form, structure, properties and classification of crystals: A. Microchemistry B. Microextraction C. Microsublimation D. Crystallography 39. The official test animal employed in the standardization of mydriatic drugs such as atropine: A. Cat B. Dog C. Horses D. Rabbit 40. Alkaline has a taste description of: A. Sour B. Sweet C. Salty D. Bitter 41. A method of evaluating plants according to the type of constituent present: A. Pharmacological B. Pharmaceutical C. Morphological D. Chemical 42. A process of extraction which involve the maceration of the drugs for a short period of time with either hot or cold water: A. Infusion B. Decoction C. Maceration D. Percolation 43. These are official tests done on living animals as well as on intact or excised organs and which often indicate the strength of a particular drug or its preparation: A. Bioassays C. Microscopic test E. Chemical assay B. Histochemical test D. Microbiological test 44. It is a form of maceration in which gentle heat (40-60 ) is applied to the drug mixture: 0 A. Decoction B. Percolation C. Infusion D. Digestion 45. This gum has pseudo-plastic property to enable ointments to hold their shape and spread readily: A. Karaya B. Xanthan C. Locust bean D. Guar E. Indian gum 46. Because mannitol is absorbed from the GIT and parenterally is not metabolized, then it is used as: A. Digestant B. Osmotic diuretic C. Acidulant D. Cathartic E. Laxative 47. Ethanol and citric acid are produced by the cellular respiration of carbohydrates, especially: A. Glucose B. Sucrose C. Fructose D. Xylose E. Lactose 48. A glucosan yield glucose units on hydrolysis, while inulin is a _____: A. Fructosan B. Hexosan C. Pentosan D. Diosan E. All of the choices 49. The following are monosaccharides, except: A. Fructose B. Glucose C. Mannose D. Sucrose 50. It is a purified carbohydrate product obtained from the inner rind of citrus fruits: A. Lactic acid B. Pectin C. Tartaric acid D. Citric acid 51. The component of starch that reacts with iodine to form a deep blue complex: A. Insulin B. Sucrose C. Amylopectin D. Amylose 52. The most important monosaccharides found in plants: A. Trioses B. Levulose C. Pentoses D. Hexoses 53. Substance producing a warm biting sensation: A. Pungent B. Acid C. Nauseous D. Astringent 54. The polyglucan used as plasma expander and is formed from sucrose by the action of the enzyme transglucosylase: A. Inulin B. Dextran C. Gelatin D. Hetastarch 55. A test for carbohydrates containing protein producing a red-blue or purple ring between the two layers: A. Molisch test B. Xanthoproteic test C. Ninhydrin test D. Biuret test 56. Substance producing a bland smooth feeling: A. Pungent B. Oily C. Mucilaginous D. Astringent 57. The primary function of plants not present in animals but on which animal and man depend greatly: A. Respiration B. Glycolysis C. Photosynthesis D. Metabolism 58. Which of the following is not a polysaccharide: A. Dextran B. Cellulose C. Sucrose D. Inulin 59. When crystals of sugar are no longer obtainable, the residual dark colored syrup is: A. Honey B. Molasses C. Sucrose D. Starch 60. A milk sugar composed of glucose and galactose: A. Sucrose B. Galactose C. Lactose D. Fructose 61. Fermenting enzymes that converts monosaccharides to ethyl alcohol and carbon dioxide: A. Rennin B. Zymase C. Urease D. Sutilains 62. Tragacanth is a dried gummy exudates from: A. Astralagus gummifer B. Astralagus gumnifer C. Acacia senegal D. A & B 63. This sugar upon hydrolysis yields 2 molecules of glucose: A. Glucose B. Sucrose C. Lactose D. Maltose 64. These are natural hydrocolloids that may be ionic, anionic or salts of polysaccharides: A. Mucilages B. Carbohydrates C. Colloids D. Gums E. None of the choices 65. This is a polysaccharide composed of glucose units joined by β-1,4 linkages and usually forms the primary cell wall of the plants: A. Suberin B. Lignin C. Cutin D. Celllulose 66. United fat globules when churred: A. Butter B. Whey C. Condense milk D. Cheese 67. The milk left after separation of the cream: A. Butter B. Butter milk C. Skimmed milk D. Condensed milk 68. This is prepared by partial evaporation of milk in a vacuum and consequent sterilization in hermetically sealed containers by autoclaving: A. Butter B. Butter milk C. Whey D. Condensed milk 69. Trisaccharide that occurs in sugar beets, seeds of cotton, and barley, a non reducing sugar: A. Gentianose B. Raffinose C. Stachyose D. Melizitose 70. This is the product obtained by the action of a mixture of nitric and sulfuric acids in cotton: A. Methylcellulose B. Gums C. Collodion D. Soluble guncotton 71. A purified carbohydrate product extracted from the brown seaweeds, Macrosystic pyriferia by the use of dilute alkali: A. Karaya gum B. Gelatin C. Algin D. Carrageenan 72. The following are homoglycans, except: A. Starch B. Inulin C. Dextran D. Pectin 73. What is the substance present in chitin that cannot be found in cellulose? A. Hydroxyl acid B. Acetamide C. Galacturonic acid D. Esters 74. One of the following is not a medicinal balsam: A. Storax B. Benzoin C. Styrax D. Tolu E. Methyl salicylate 75. Among the anthraquinone glycosdies, this is not employed as cathartic because it is too irritating to use: A. Aloe B. Frangula C. Rhubarb D. Senna E. Chrysarobin 76. Source of arbutin, a phenol containing glycoside: A. Buckwheat B. Checkerberry C. Bearberry D. Dragonfruit 77. Which of the following is classified as an alcohol glycoside: A. Salicin B. Gentisin C. Cantharidin D. Entadin 78. Which of the following glycosides yield HCN as one of the products of hydrolysis: A. Amygdalin B. Sinigrin C. Sinalbin D. None of the choices 79. Which of the following glycosides represent the group of bound poisons: A. Glucosinolates B. Cyanophore C. Anthraquinone D. Lactone 80. Most of the glycosides are subject to hydrolysis, resulting the cleavage of glycoside linkages, by: A. Acid or enzyme B. Alkali C. Both A & B D. None of the choices 81. Which of the following glycosides yield allyl isothiocyanate as one of the products of hydrolysis: A. Amygdalin B. Prunasin C. Sinigrin D. Sinalbin 82. These are derivatives of mandelonitrile: A. Cyanophore glycosides B. Glucosinolates C. Both A & B D. Saponin 83. Glycosidic principle obtained from fish berries, Cocculus indicus formerly used as an analeptic: A. Quassin B. Humulin C. Picrotoxin D. Gentisin 84. Glycoside found in garlic which possesses anti-platelet, anti-microbial and anti-rheumatic properties: A. Allicin B. Berberine C. Cantharmin D. Sanguinarine 85. Flavonoid found in yellow flower pigments: A. Flavonoids B. Xanthones C. Anthocyanins D. Bioflavonols 86. It destroys red blood corpuscles by hemolysis and are toxic especially to cold-blooded animals: A. Saponin glycoside C. Cyanogenic glycosides B. Anthraquinone glycosides D. Flavonol glycosides 87. Enzymes that hydrolyze a considerable number of glycosides: A. Invertase B. Maltase C. Emulsin and myrosin D. Lactase 88. Hallucinogenic agent derived from Cannabis sativa includes: A. Tetrahydrocannabinol B. Scopolamine C. Emetine D. All of the choices 89. An oleoresin used extremely as counterirritant: A. White pine B. Balsam of Peru C. Turpentine D. None of the choices 90. Glycoside found in cassava: A. Mandelonitrile B. Cyanohydrine C. Mannihotoxin D. Hydrocyanic acid 91. Pigment of flowers which is of glycosidic character: A. Xanthophyll B. Cytochrome C. Anthocyanins D. Lutein 92. Medicinal effects and potencies of cardio-active glycosides depend on: A. Digitalase C. Genin structure and glycone component B. Glucose D. Cadiac/cadiotonic effect 93. This is also known as 4-hydroxyl-3-methoxy benzaldehyde popularly used as flavoring agent: A. Eugenol B. Glycyrrhizin C. Coumarin D. Vanillin 94. Glycosides are also known as: A. Sugar-ether B. Sugar-ester C. Sugar-acids D. None of the choices 95. The enzyme in black mustard seed that hydrolyzes the glycoside: A. Emulsin B. Amygdalase C. Myrosin D. Papain 96. Glycosidic volatile oils are obtained by: A. Expression B. Ecuelle method C. Enzymatic hydrolysis D. Destructive distillation 97. The non-sugar portion of a glycoside is known as: A. Glycone B. Genin C. Inactive portion D. Active 98. These are acetal in which the hydroxyl of the sugar is condensed with a hydroxyl group of the non-sugar component: A. Tannins B. Carbohydrates C. Resins D. Glycosides 99. Active principle in ginseng is classified as a _____ glycoside. A. Anthraquinone B. Flavonoid C. Saponin D. Alcohol 100. Indian hemp or Marijuana is classified under what family?: A. Moraceae B. Poaceae C. Lamiaceae D. Arecaceae 101. Which of the following yield a phenolic compound as one of its products of hydrolysis: A. Arbutin B. Salicin C. Glucovanillin D. None of the choices 102. Which of the following contains 60-70% of Bassorin? A. Acacia B. Indian gum C. Tragacanth D. Karaya gum 103. It forms a colloidal solutions in water that foam upon shaking, and destroys the RBC by hemolysis: A. Tannins B. Alkaloids C. Saponins D. Fats 104. Which of the following pairs is correct: A. Frangula-anthraquinone glycoside C. Senna-phenol glycoside B. Aloe-saponin glycoside ` D. Dioscorrea-cyanophore glycoside 105. Cardiac glycosides are obtained from: A. Gamboges B. Strophanthus C. Opium D. All of them E. None of them 106. Based on the chemical nature of the aglycone, glycosides may be classified as: A. Saponin-containing C. Flavonoids E. Phenolic B. Cyanophoric D. All of the choices 107. Anthraquinone glycosides are exemplified by the following, except: A. Digitalis B. Cascara sagrada C. Frangula D. Aloe E. Rhubard 108. The principal anthraquinone glycoside of aloe is _____: A. Barbaloin B. Aloin C. Iso-barbaloin D. Aloe emodin E. None of them 109. Use of chrysarobin: A. Cathartic B. Condiment C. Flavorant D. Keratolytic 110. Glycosides’ non-sugar moiety is called: A. Aglycone B. Agenin C. Glucoside D. Glycone 111. Glycosides can be hydrolyzed by: A. Alcohol B. Heat C. Light D. Water 112. Lily of the valley is employed as cardiac stimulant, this is obtained from: A.Convallaria majalis B. Digitalis purpurea C.Strophantus gratus D. Tinosphora rumphi 113. What is the pungent-tasting oil that is produced by the hydrolysis of Sinapis alba? A. Mustard oil B. Sinalbin C. Acrinylisothiocyanate D. Allylisothiocyanate 114. This plant is containing quercetin and used as antibiotic and antiseptic: A. Onion B. Garlic C. Ginger D. Weed 115. Glycosides found in the cambial layer of Pine trees: A. Vanillin B. Coumarin C. Sapogenin D. Coniferin 116. All belong to anthraquinone group of glycosides, except: A. Anthranols B. Saponins C. Aloin-type D. Oxanthrones 117. Borntrager test is used for the detection of: A. Saponin B. Alkaloid C. Volatile oils D. Anthraquinone 118. This is classified as lactone glycoside: A. Santonin B. Coumarin C. Cantharidin D. Arbutin 119. Sinigrin is hydrolyzed by the enzyme _____: A. Beta-amylase B. Myrosin C. Ptyalin D. Emulsin 120. The product of amygdalin hydrolysis is/are: A. Hydrocyanic acid B. Benzaldehyde C. A & B D. None of them 121. The active constituent of saffron is: A. Myrosin B. Sinigrin C. Picrosin D. Crosin 122. _____ is a vesicating principle from Spanish files: A. Cantharidin B. Picrotoxin C. Crocin D. Picretin 123. Which of the following health problems could aggravate by increased consumption of large quantities of licorice? A. Peptic ulcer B. Addison’s disease C. Gastric acidity D. Hypertension 124. Tannins have the ability to precipitate _____ which is utilized in vegetable tanning which converts animal hides to leather: A. Fats B. Carbohydrates C. Alkaloids D. Proteins E. Glycosides 125. The mixtures of polyphenols that is difficult to crystallize: A. Glycosides B. Resins C. Alkaloids D. Tannins 126. The usual source of tannins from plants is from the: A. Barks/stems B. Seeds C. roots D. Rhizomes E. All of these 127. The following is/are the properties of non-hydrolysable tannins, except: A. They give a bluish to black color with ferric chloride B. They usually contain phloroglucinol nucleus in part C. They are usually precipitated by bromine water TS D. They yield catechol when heated 128. The following is/are the properties of the hydrolysable tannins, except: A. They give a dark green color with ferric chloride TS B. Gallic acid when heated result to formation or pyrogallol C. They yield no precipitate with bromine water TS D. Pyrogallol give soluble compounds with lead acetate 129. Generally accepted medicinal use of tannins: A. Tanning of leather C. Laboratory precipitant B. Astringent D. As ingredient in the preparation of ink 130. Hydrolyzable tannins are characterized as: A. Yielding gallic acid when hydrolyzed B. Turns bluish-black with Ferric chloride TS C. Converted to pyrogallol on dried distillation D. All of the choices E. None of the choices 131. The most notable property of tannins utilized in the leather industry: A. Denature proteins B. Precipitate protein C. Denature proteins and precipitate protein D. None of the above 132. This is responsible for the astringent and antiseptic actions of tannin: A. Aldehyde B. Ketone C. Phenolic D. Carboxylic 133. The following are differences of hydrolysable from non-hydrolysable tannins, except: A. Hydrolysable tannins form blue-black precipitates with ferric chloride B. Non-hydrolysable tannins decolorize potassium permanganate C. Hydrolysable tannins show no visible result with bromine water D. None of the above choices 134. Tannins is an effective antidote to _____ poisoning: A. Alkaloid B. Phosphorous C. Insecticide D. Lead 135. Another name for which frangula is known for is _____: A. Cinnamon bark B. Buchthorn bark C. Cascara bark D. Cassia bark 136. Tannins are characterized as: A. Amorphous, polyhydroxy-phenolic compounds B. Possessing an astringent taste C. None of the above D. Both A & B 137. The common name of Areca catechu is: A. Niogniogan B. Bunga C. Peanut D. Pilinut 138. The usual source of fixed oils: A. Flowers B. Seeds C. Leaves D. Stems E. Roots/rhizomes 139. It is a liquid animal fat: A. Coconut oil B. Peanut oil C. Theobroma D. Cod liver oil 140. This is a solid vegetable oil: A. Coconut oil B. Peanut oil C. Theobroma D. Cod liver oil 141. These are lipid metabolites formed in the body of animals from unsaturated fatty acids of the diet: A. Carnauba B. Bayberry C. Spermaceti D. Prostaglandin E. Lanolin 142. These are esters consisting of glycerol in combination with fatty acids, phosphoric acid and certain nitrogenous compounds: A. Phospholipids B. Waxes C. Fixed oils D. Sterols 143. These are esters of high molecular, monohydric alcohols and high molecular fatty acid: A. Waxes B. Phospholipids C. Glycolipids D. Sphingomyelins 144. The purified fatlike substance obtained from the wool of sheep: A. Lanolin B. Cetyl esters wax C. Cysteine D. Spermaceti 145. The wax present in beeswax is: A. Ceryl stearate B. Myricyl cerotate C. Myricyl palmitate D. Ceryl plamitate 146. Component of lecithin and a precursor of acetylcholine: A. Choline B. Biotin C. Yeast D. PABA 147. The following fixed oils are used as solvent for IM injections, except: A. Sesame oil B. Peanut oil C. Corn oil D. Olive oil 148. A medicinally important lipid which is used as a sclerosing agent: A. Jojoba oil B. Chaulmoogra oil C. Licopodium D. Sodium morrhuate 149. Drying properties of vegetable oils is based on the ability to absorb _____ from the air: A. Oxygen B. Hydrogen C. Helium D. Argon 150. Fixed oils are frequently extracted from their sources by: A. Expression B. Steam distillation C. Filtration E. None of the choices 151. Which of these lipids are used to control the consistency of creams and ointments? A. Cholesterol B. Waxes C. Stearic acid D. Lecithin 152. The following chemical constants are used to characterize lipids, : A. Acid number C. Saponification value E. All of the choices B. Iodine number D. Ester number 153. The type of rancidity of the oils is due to the free fatty acids liberated when the fat is hydrolyzed: A. Oxidative B. Hydrolytic C. Any of them D. None of them 154. A fixed oil obtained from the ripe fruit of a plant sometimes referred to as sweet oil: A. Olive oil B. Peanut oil C. Soybean oil D. Castor oil E. Sesame oil 155. Arachis oil is another name for _____: A. Olive oil B. Peanut oil C. Soybean oil D. Castor oil E. Sesame oil 156. Teel oil or benne oil are another names for _____: A. Olive oil B. Peanut oil C. Soybean oil D. Castor oil E. Sesame oil 157. A fixed oil termed as “food for the gods”: A. Theobroma oil B. Sunflower oil C. Peanut oil D. Safflower oil E. Coconut oil 158. A substance obtained from the head of the sperm whale, Physeter macrocephalus L.: A. Spermaceti C. Cetyl alcohol E. Cetyl laurate B. Cetyl ester wax D. Stearyl alcohol 159. It indicates the number of milligrams of potassium hydroxide required to neutralized the free acids and saponify the esters contained in 1 g of the substance: A. Acid value B. Sapofonication value C. Iodine value D. Ester value 160. This oil is cathartic in action: A. Castor oil B. Olive oil C. Peanut oil D. Sesame oil 161. Which of the following statement/s pertaining to lanolin is/are correct: I. Fatlike substance from the wool of Ovies aries II. It contains not more than 0.25% of water III. It is referred to as wool fat IV. It is used as water-absorbable ointment base A. I only B. I and III C. II and III D. I and IV 162. These are substances grouped together on the basis of their insolubility in water and solubility in most organic solvents: A. Alkaloids B. Carbohydrates C. Lipids D. Proteins 163. An acid which is considered as a universal precursor for fatty acids, lipids and other organic plants products: A. Gallic acid B. Malic acid C. Citric acid D. Acetic acid 164. A substance present in soybean that can be found in number of proprietary products that are useful in controlling derange lipid and cholesterol metabolism: A. Ergosterol B. Lecithin C. Resin D. Ricin 165. It is the predominant fatty acid constituent of rapeseed oil from Brassica napus (Brassicaceae): A. Erucic acid B. Linoleic acid C. Linolenic acid D. Oleic acid 166. Citrus volatile oils whose aroma is injuriously affected by heat is best obtained by: A. Expression B. Maceration C. Enfleurage D. Percolation 167. Oil tubes found in plants under Apiaceae family that contain the volatile oil: A. Parenchyma cells B. Glandular cells C. Vitae D. Schizogenous passages 168. Japanese peppermint is solely employed as a source of: A. Terpinol B. Menthol C. Borneol D. Carvacrol 169. The principal component of volatile oil: A. Terpenes B. Aldehyde C. Lactose D. Esters 170. The active constituent of Clove oil is: A. Coneferin B. Methyl salicylate C. Anethol D. Eugenol 171. A ketone volatile oil that is used as antipruritis: A. Eucalyptol B. Spearmint C. Camphor D. Peppermint 172. All of these are volatile oils that are used as condiments, except: A. Anise B. Olive oil C. Nutmeg D. Eucalyptus oil 173. The volatile oil from this plant is an Anethole: A. Almond B. Turpentine C. Clove D. Anise 174. This plant is a source of drug for antimalaria and anticancer: A. Artemisia annua B. Gingko biloba C. Coleus forskohlii D. Piper nigrum 175. Which of the following is phenol volatile oil? A. Anise B. Thyme C. Fennel D. Eucalyptus 176. Source of castor oil: A. Jatropha curas B. Michelia champaca C. Ricinus communis D. Croton tiglium 177. Which of the following is the active constituents of wintergreen oil: A. Phenol B. Alcohol C. Menthol D. Methyl salicylate 178. Volatile oil are isolated by: A. Solvent extraction B. Destructive distillation C. Steam distillation D. All of the choices E. None of the choices 179. Volatile oils may occur in the _____ of the plant: A. Oil cells B. Glandular hairs C. Ducts D. A, B, & C E. None of the choices 180. Volatile are used for _____: A. Therapeutic action B. Flavoring C. Perfumery D. All of the choices 181. Volatile oils are usually obtained by steam distillation, with the exception of the oils from: A. Pinaceae B. Rutaceae C. Umbellifereae D. Rosaceae 182. Ascaridol is obtained from the fresh flower and fruits of: A. Cajuput B. Chenepodium C. Lavender D. Bergamot 183. Ascaridol, a volatile oil constituent obtained from the chenopodium oil is/an: A. Oxide B. Furan derivative C. Alcohol D. Phenol 184. Which of the following oil is not an alcohol containing volatile oils: A. Peppermint B. Cardamon C. Coriander D. Lemon 185. In the enfleurage method, the fatty product impregnated with the floral odor is called: A. Absolutes B. Terpenes C. Concretes D. Pomade 186. Oils which are lighter than water are usually rich in the following, except: A. Alcohol B. Hydrocarbon C. Esters D. Ketone E. Aldehyde 187. Juniper tar oil is obtained from the woody portion of the tree and also known as: A. Cade oil B. Neroli oil C. Fennel oil D. Sassafras oil 188. Each of the following volatile oils has an aldehyde as a major constituent, except: A. Ceylon cinnamon oil B. Lemon oil C. Camphor oil D. Cassia cinnamon oil 189. Each of the following volatile oil has a hydrocarbon as a major constituent, except: A. Turpentine oil B. Lemon oil C. Pepper oil D. Rose oil 190. The following are alcohol containing volatile oil, except: A. Peppermint B. Cardamon C. Coriander D. Rose 191. The solid, oxidized hydrocarbon portion of volatile oils: A. Stearoptene B. Eleoptene C. Stearic acid D. None of the choices 192. It contains ocimene, eugenol and pimene and a decoction of this herb is for treatment of cough: A. Foeniculum vulgare B. Bixa orellana C. Ocimum basilicum D. None of the choices 193. Component of volatile oil which is responsible for its antiseptic and germicidal action: A. Ethers B. Phenols C. Hydrocarbons D. Esters 194. Volatile oil plays a vital role in plants as: A. Astringents C. Insect repellants/attractants B. Protein synthesizer D. Cellular processes 195. Active constituent of the volatile oil of tanglad which is very good source of vitamin A: A. Geraniol B. Citral C. Citronellal D. Citronellol 196. Method of extracting volatile oil with the use of cold fat: A. Enfleurage B. Digestion C. Percolation D. Maceration 197. Gaultheria oil belongs to this family: A. Pinaceae B. Brassicaceae C. Rutaceae D. Ericaceae 198. The other name of Myristica is: A. Anise B. Nutmeg C. Cinnamon D. Fennel 199. If the percent of extractive from a crude drug represent a single chemical species, the assay is referred to as a: A. Proximate C. Ultimate B. Gravimetric D. Volumetric 200. All are volatile constituents of peppermint oil, except: A. Menthol B. Menthyl acetate C. Carvacrol D. Limonene E. Menthone 201. This oil is classified as an ester volatile oils: A. Mustard B. Rose C. Chenopodium D. Anise 202. The basic unit of terpenes is _____: A. Eleoptene B. Stereoptene C. Isoprene D. Sesquiterpene E. Diterpene 203. Volatile oils and volatile-containing drugs are categorized as: A. Alcohols B. Ketones C. Esters D. A, B, & C E. None of them 204. Volatile oils: I. Cannot be distilled from natural sources II. Consists of glyceryl esters of fatty acids III. Leave a permanent grease spot on paper IV. Do not become rancid A. I, II, III B. II and III C. III only D. IV only 205. Volatile oils are differentiated from fixed oils by: A. Acrolein test B. Iodine test C. Ozasone test D. Stain 206. The following statements are true about volatile oils, except: A. They are odoriferous principles of plants and animals B. Most are soluble in alcohol C. They are optically active D. Refractive indices are usually in range 207. These are resinous mixtures that contain cinnamic acid, benzoic acid or esters of these acids: A. Balsams B. Rosin C. Resins D. Resenes E. None of these 208. The active constituent of Capsicum frutescens: A. Capsicin B. Capsaicin C. Capsin D. B & C E. A & B 209. A resin which is used as a diaphoretic: A. Ginger B. Capsicum C. Hashish D. Pistachio 210. The solid resin from turpentine: A. Benzoin B. Styrax C. tolu D. Rosin 211. These are usually hard, transparent, or translucent and when heated, they soften and finally melt: A. Alkaloids B. Resins C. Gums D. Tannins 212. Resins are classified as: A. Basic resin C. Neutral resin B. Acid resin D. Mixed resin 213. The term RESIN usually apply to: A. Solid, amorphous product of complex chemical structure B. Hard, transparent or translucent exudates C. Soften and finally melts upon standing D. All of the choices 214. Balsams contain a high proportion of aromatic, balsamic acids, chiefly: A. Benzoic acid B. Cinnamic acid C. Both A & B D. Neither A or B 215. Which of the ff. is an antifungal ointment with benzoic and salicylic acid as ingredients: A. Penicillin ointment B. Terramycin ointment C. Whitfield’s ointment D. None of them 216. Resin obtained from the rhizome and roots of mayapple or mandrake and used as purgative: A. Rosin B. Peltatin C. Zingerone D. Capsaicin 217. The Scientific name of Jalap is: A. Cannavis sativa B. Phodophyllum peltatum C. Pinus pallustris D. Exogonium purga 218. Balsam obtained from the trunk of Liquidambar orientalis that is used as a pharmaceutic aid for compound benzoin tincture: A. Peruvian balsam B. Tolu balsam C. Storax D. Styrax 219. A resinous exudates from Pistacia lentiscus that is used in the form of dental varnish to seal cavities: A. Eriodictyon B. Jalap C. Mastic D. Kava 220. Turpentine from Pinus pallustris is used as: A. Laxative B. Diuretic C. Counter irritant D. Anthelmintic 221. The principal cinchona alkaloid employed therapeutically as anti-protozoal drug: A. Quinine B. Chloroquine C. Quinacrine D. Quinidine E. Eserine salicylate 222. The alkaloid in the form of syrup is used in the treatment of drug overdose in certain poisonings: A. Hydrates B. Ipecac C. Quinine D. Ergotamine E. Morphine 223. Solution of Potassium Bismuth Iodide is: A. Mayer’s B. Wagner’s C. Valser’s D. Draggenddorf’s 224. This alkaloid is employed in ophthalmology to treat glaucoma: A. Eserine B. Reserpine C. Emetine D. Morphine E. Strychnine 225. The alkaloid formed by the acetylation of morphine is: A. Heroin B. Codeine C. Morphine D. Cocaine E. Papaverine 226. The alkaloid present in Rauwolfia is: A. Emetine B. Reserpine C. Physostigmine D. Morphine E. Scopolamine 227. Alkaloids obtained from opium and its extract, except: A. Codeine B. Morphine C. Noscapine D. Thebaine E. Cocaine 228. The most widely used opium alkaloid is: A. Heroin B. Codeine C. Morphine D. Narcotine E. Papaverine 229. The most important of the opium alkaloids is: A. Heroin B. Codeine C. Morphine D. Narcotine E. Papaverine 230. This is used as an antidote for alkaloidal poisoning: A. Lactic acid B. Tannic acid C. Tartaric acid D. Picric acid E. Gallic acid 231. In general, alkaloids may be identified by: A. Specific rotation C. Color reactions with specified reagents B. Solubility in various solvents D. All of the above 232. Mercuric iodide, Potassium iodide and water are the composition of: A. Mayer’s reagent C. Wagner’s reagent B. Dragendorff’s reagent D. All of these 233. To convert an alkaloid salt into a free base, the following should be added: A. Sodium carbonate C. Petroleum ether B. Tartaric acid solution D. None the choices 234. Cocaine has a long duration of local anesthetic action because it is a: A. Bronchoconstrictor C. Vasodilator B. Bronchodilator D. Vasoconstrictor 235. The plant material is treated with ammonium hydroxide in order to: A. Convert alkaloidal salts into free base B. Convert free bases into alkaloidal salts C. Both A & B D. None of the above 236. The most active alkaloids in betel nut: A. Arecaidine B. Arecoline C. Nicotine D. Sparteine 237. Which of the following is the usual type of alkaloid? A. Primary B. Secondary C. Tertiary D. Quaternary 238. All these drugs contain caffeine, except: A. Coffee B. Cola C. Tea D. Coca 239. Caffeine belongs to this class of alkaloids: A. Cinchona alkaloids B. Ergot alkaloids C. Xanthine alkaloids D. Vinca alkaloids 240. The element responsible for the basic pharmacological properties of alkaloids: A. Sulfur B. Nitrogen C. Oxygen D. Phosphorus 241. 1, 3, 7-trimethyl xanthine is the chemical name of: A. Caffeine B. Theophylline C. Theobromine D. Thebaine 242. Codeine which is used as an analgesic and depressant to the cough reflex is a derivative of: A. Benzoic acid B. Cocaine C. Salicylic acid D. Morphine 243. Which of the following is an anti-hypertensive and psychotherapeutic alkaloid: A. Physostigmine B. Quinine C. Papaverine D. Reserpine 244. An alkaloid which does not react with or form precipitate with alkaloidal reagent is: A. Hyoscyamine B. Quinine C. Atropine D. Caffeine 245. The hallucinogen derived from ergot: A. THC B. ETO C. EDTA D. LSD 246. A drug which disguises the bitter taste of quinine by paralyzing the taste buds is: A. Glycyrrhiza B. Yerba soldado C. Buchu D. Yerba santa 247. The alkaloid obtained from ergot which is used to relieve or treat migraine is: A. Ergometrine B. Vinblastine C. Ergotamine D. Solanine 248. The organism used in the parasitic method of producing Ergot alkaloids: A. Claviceps purpurea B. Claviceps paspali C. A & B D. None of these 249. Plant sources of purine bases alkaloids: A. Kola B. Tea C. Cacao D. All of the choices 250. Plant sources of tropane alkaloids, except: A. Belladonna B. Stramonium C. Hyoscyamus D. Senna 251. The alkaloid reagent composed of Iodine, in potassium iodine solution is known as: A. Hager’s reagent B. Mayer’s reagent C. Dragendorff’s reagent D. Wagner’s reagent 252. Most of the alkaloids are crystalline solid and which of the ff. is not a liquid alkaloids: A. Conine B. Nicotine C. Sparteine D. None of the choices 253. The alkaloid which continues to bed the drug of choice against malaria: A. Cincholine B. Quinine C. Papaverine D. Argonovine 254. This is the most widely used opium alkaloid which are narcotic analgesics and anti- tussives and are used as sedatives, especially in allaying coughs: A. Morphine B. Papaverine C. Codeine D. Heroine E. None of the choices 255. The following alkaloid are present in Datura metel, except: A. Atropine B. Caffeine C. Hyoscyamine D. Scopolamine 256. The alkaloid found in calabar bean: A. Physostigmine B. Cocaine C. Cochicines D. Emetine 257. Most of the alkaloids are optically active but not those belong to this group: A. Indole B. Purine C. Pyridine D. Tropane 258. An alkaloid which does not react with or precipitate with alkaloidal reagent is: A. Caffeine B. Quinine C. Hyoscyamine D. Emetine 259. Gotu Kola obtained from the leaves and stems of Centella asiatica used as diuretic, blood purifier, treats leprosy, body strengthener and revitalize is locally known as: A. Takip-kuhol B. Sulasi C. Lagundi D. Mahogany 260. The following are alkaloidal reagents, except: A. Million’s reagent B. Mayer’s reagent C. Dragendorff’s reagent D. Wagner’s reagent 261. Pilocarpine, an imidazole alkaloid is employed for the treatment of: A. Bronchial asthma B. Hypertension C. Motion sickness D. Glaucoma 262. A CNS stimulant obtained from Nux vomica: A. Venleurosine B. Ergotoxine C. Brucine D. Strychnine 263. Alkaloid obtained from Sarothammus scorparius which was formerly used for cardiac arrythmias: A. Sparteine B. Coniine C. Thebaine D. Levuline 264. Strychnine and brucine belong to: A. Ergot alkaloids B. Isoquinoline alkaloids C. Indole alkaloids D. Cinchona alkaloids 265. Type of alkaloid that does not have heterocyclic ring with nitrogen but derived from amino acids: A. True alkaloids B. Proto alkaloids C. Pseudo alkaloids D. Any of the choices 266. Isolated morphine in 1804: A. Ehrlich B. Coventeau C. Plank D. Serturner 267. Which of the ff. alkaloids has heterocyclic ring with nitrogen and derived from amino acids: A. Nicotine B. Colchicine C. Caffeine D. Theophylline 268. This plant contains Coniine and also called poison hemlock: A. Pomegranate B. Tobacco C. Conium D. Belladona 269. Talumpunay is scientifically known as: A. Datura metel L. B. Datura alba L. C. Datura nigra Blanco D. Datura sophora Mill. 270. The following statement about alkaloids are true, except: A. They contain nitrogen usually in heterocyclic ring B. Most of them are physiologically active even in small amounts C. Alkaloidal salts are soluble in organic solvents D. They are precipitated by Mayer’s reagent, Wagner’s reagent & Valser’s reagent 271. The _____ group of alkaloids are derived from Papaver somniferum (Fam. Papaveraceae): A. Cinchona alkaloids B. Ergot alkaloids C. Opium alkaloids D. Vinca alkaloids 272. The genus Cinchona (Fam. Rubiaceae) produce the _____ group of alkaloids: A. Piperidine alkaloids B. Pyridine alkaloids C. Quinoline alkaloids D. Tropane alkaloids 273. The most characteristic physiological property of alkaloids from family Solanaceae is their: A. Analgesic effect C. Miotic effect B. Antri-inflammatory effect D. Mydriatic effect 274. Constituent of Claviceps purpurea employed as a uterine muscle relaxant: A. Pilocarpine B. Ergotoxine C. Ergotamine tartarate D. Ergonovine maleate 275. An alkaloid used to reduce rigidly and tremors for those suffering from Parkinson’s disease: A. Atropine B. Hyoscine C. Hyoscyamine D. Scopolamine 276. An alkaloidal plant that could be used in the eyes causing dilation of the pupil of the eye giving a striking appearance: A. Nicotiana leaf B. Belladonna leaf C. Coca leaf D. Arrow root 277. Which of the following amino acids is the least used as precursor in the biosynthesis of alkaloid? A. Phenylalanine B. Adenine C. Ornithine D. Tyrosine 278. _____ is the amino acid precursor of indole alkaloids via anthranilic acid: A. L-histidine B. L-lysine C. L-tryptophan D. L-tyrosine 279. It is a uterine stimulating fraction and it is relatively free from action on other smooth muscle: A. Liotrix B. Oxytocin C. Sodium dextrothyroxine D. Vasopressin 280. Class of natural products with potent and diverse biological activities involved in platelet aggregation, pain and inflammation: A. Enzyme B. Hormones C. Prostaglandins D. Tubocurarine 281. The following statements pertain to glucagon, except: A. It is produced by the β-cells B. Exert counterbalancing action on carbohydrate metabolism in the body C. Elicits a hyperglycemic response in the body D. It is formed by a α-cells 282. The following conditions characterize thyroid hyperactivity, except: A. Muscle weakness with tremor C. Increase in heart rate and blood pressure B. Loss of body weight and fat D. Increased tolerance to heat but intolerance to cold 283. This hormone regulates the threshold for resorption of water by the epithelium of renal tubules and has an anti-diuretic principle: A. Vasopressin B. Oxytocin C. Adrenocorticotropin D. Chorionic gonadotropin 284. This is a gonad-stimulating polypeptide hormone obtained from the urine of pregnant women: A. Vasopressin B. Oxytocin C. Adrenocorticotropin D. Chorionic gonadotropin 285. Dopamine is: I. 4, 3-dihydroxyphenylethylamine II. Acts directly to stimulate beta-2 receptors III. Biosynthetic precursor of norepinephrine and epinephrine IV. Used to treat patients with acute hypertension A. II & III B. I only C. III only D. Both I, III, & IV 286. This is purified preparation of gonadotropins obtained from the urine of postmenopausal women: A. Choriogonadotropin B. Urogonadotropin C. Somatropin D. Gonadorelin 287. This hormone is used in the treatment of Paget’s disease and postmenopausal osteoporosis: A. Calcitonin B. Insulin C. Calcium D. Cholecystokinin 288. Intrinsic factor of pernicious anemia: A. Cyanocobalamin B. Hemoglobin C. Ferrous D. All of the above 289. Which of the following vitamins is a precursor of coenzyme A? A. Cobamide B. Panthothenate C. Thiamine D. Riboflavin 290. Yeast is rich source of: A. Riboflavin B. Folic acid C. Ascorbic acid D. Thiamine 291. Free vitamin A does not occur in plants, but in its place are compounds that are converted into, vitamin A in the small animal body. These precursors of vitamin A are called: A. Provitamin B B. Neovitamin A C. B-carotene D. B & C 292. Which vitamin is formed in the body by exposure to ultraviolet irradiation or sunlight? A. Vitamin E B. Vitamin D C. Vitamin A D. Vitamin C 293. A plant pigment of therapeutic importance in preventing xeropthalmia is: A. Carotene B. Xanthophylls C. Fucoxanthine D. Chlorophyll 294. Also known as vitamin H which acts as a carboxyl-carrying cofactor in several carboxylase enzyme system: A. Choline B. Biotin C. Yeast D. PABA 295. Rutin and hesperidin combination is also known as: A. Vitamin F B. Vitamin P C. Vitamin H D. Vitamin K 296. This is a naturally occurring pyridine derivative the prevents pellagra: A. Riboflavin B. Niacin C. Pyridoxine D. Mendione 297. Ergosterol is: A. Principal sterol in soybeans B. Known as provitamin D2 C. Widely distributed throughout the plant kingdom D. One of the chief constituents of lanolin 298. A mixture of protein-digesting and milk clotting enzymes obtained from the juice of the pineapple plant: A. Chemotrypsin B. Bromelain C. Lactase D. Sotilains 299. A muccopolysaccharide obtained from saliva which is active against Gram (+) bacteria, by transforming the insoluble polysaccharides: A. Muramidase B. Lysozyme C. A & B D. None of the choices 300. Which of the following terms best describes a cofactor that is firmly bound to an apoenzyme: A. Holoenzmyes B. Nucleosides C. Monosaccharides D. Heteropolysaccharides 301. These are organic catalyst produced by living organisms: A. Enzymes & protein B. Biologics C. Vitamins D. Peptide hormones 302. This enzyme causes the hydrolysis of fats into glycerin and fatty acids: A. Pectase B. Lipase C. Urease D. Trypsin 303. This enzyme bring about the oxidation reactions that cause the discoloration of bruised fruits: A. Peroxidases B. Zymase C. Pepsin D. Typsin Page 1 of 19