Final Exam of Biochemistry (Copy A) PDF

7/17/2021 Final exam of Biochemistry (copy A) Final exam of Biochemistry (copy A) The name, username and photo associated with your Google account will be recorded when you upload files and submit this form....

7/17/2021 Final exam of Biochemistry (copy A) Final exam of Biochemistry (copy A) The name, username and photo associated with your Google account will be recorded when you upload files and submit this form. Not [email protected]? Switch account * Required Q.1. Choose one answer only for each of the following: (60 Marks) 1. Cyclic AMP promoting the simultaneous of: * 1 point Activation of phosphorylase and inhibition of glycogen synthase Activation of phosphorylase and activation of glycogen synthase Activation of phosphatase and activation of glycogen synthase Activation of phosphatase and inhibition of glycogen synthase 2. The anterior pituitary gland secretes hormones that: * 1 point Antagonize action of Cortisol Antagonize action of insulin Antagonize action of epinephrin Similar action of insulin https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 1/20 7/17/2021 Final exam of Biochemistry (copy A) 3. Glycogen synthase is the regulatory enzyme of glycogenesis. It exists in 1 point two forms: Glycogen synthase-a as: * Inactive or phosphorylated form. Active or dephosphorylated form Inactive or dephosphorylated form. Active or phosphorylated form 4. Gluconeogenesis is decreased by: * 1 point Epinephrine Glucagon Glucocorticoids Insulin 5. G-1-P converted to UDP-glucose by: * 1 point UDP- fructose pyrophosphorylase UDP- glucose phosphatase UDP- glucose pyrophosphorylase UDP- glucose kinase https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 2/20 7/17/2021 Final exam of Biochemistry (copy A) 6. Which of the following processes are likely to be enhanced shortly after 1 point a carbohydrate-rich meal? * Glycogenolysis Growth hormone secretion Cortisol secretion Glycogenesis 7. These tissues that are not insulin-sensitive are: * 1 point kidney Lens and liver Lens, Peripheral nerves and renal glomerular Liver and kidney 8. The activity of G6PD is regulated by: * 1 point NADH NADPH FAD FADH https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 3/20 7/17/2021 Final exam of Biochemistry (copy A) 9. Cori’s cycle transfers: * 1 point Lactate from liver to muscles Lactate from muscles to liver Glucose from muscles to liver Pyruvate from liver to muscles 10. HFI is an inborn error of: * 1 point Furanose and fructose metabolism Fructose metabolism Glucose metabolism Furanose metabolism 11. Glucokinase has: * 1 point Higher Km (higher affinity) Lower Km (higher affinity) Higher Km (lower affinity) Lower Km (lower affinity) 12. Propionyl-CoA produced by oxidation of odd carbon number of: * 1 point id d b k l f i id https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 4/20 7/17/2021 Final exam of Biochemistry (copy A) Fatty acids and carbon skeleton of some amino acids. Fatty acids and glucose None of these Amino acids and glucose. 13. Glycogen a branched polymer of: * 1 point D-glucose L-aldose L-fructose L-glucose 14. Pyruvate converted to alanine by: * 1 point Alanine kinase Aspartate transferase(AST) All of these Alanine transferase (ALT) 15. Ethanol oxidation,the increase NADH produced in the liver interferes 1 point with: * All of these Gluconeogenesis Glycogenesis Glycogenolysis https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 5/20 7/17/2021 Final exam of Biochemistry (copy A) 16.The initial steps in glycogen synthesis involve the protein Glycogenin to 1 point form: * All of these Glycogen Glycogen primer UDPGlc 17. Glucagon activated by: * 1 point cATP ADP GDP cAMP 18. Branching enzyme: * 1 point Transfers a part of the 1 – 4 chain to a neighboring chain to form a 1 -6 linkage Act when a growing chain is at least 18 glucose residues long All of these Transfers a part of the 1 – 6 chain to a neighboring chain to form a 1 -4 linkage https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 6/20 7/17/2021 Final exam of Biochemistry (copy A) 19. Glucose-6-phosphate can be formed from glucose 1-phosphate 1 point Catalyzed by: * phosphatase Phosphoglucomutase Phosphorylase 1-6-glycosidase 20. In glycogenolysis Glycogen phosphorylase catalyzes to yield: * 1 point Glucose 6-phosphate. Glucose Glucose 3-phosphate Glucose 1-phosphate 21. Porphobilinogen synthase (delta-aminolevulinic acid dehydratase): * 1 point present in mitochondria inhibited by lead. requires pyridoxal (vitamin B6) phosphate for activity. is the control step in heme synthesis. https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 7/20 7/17/2021 Final exam of Biochemistry (copy A) 22. Hydroxyproline and hydroxylysine are formed by hydroxylation of 1 point proline and lysine, the reaction catalyzed by prolyl and lysyl hydroxylase. Which of the folloing serve as coenzyme? * None of these Biotin Acsorbate thiamine 23. All the following protein consider as hemoproteins: * 1 point Myoglobin Cytochrome c Catalase. All of these 24. The serine formation includes: * 1 point None of these Dehydrogenation and subsequent decarboxylation Transamination and subsequent dephosphorylation Transamination and subsequent decarboxylation https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 8/20 7/17/2021 Final exam of Biochemistry (copy A) 25. Leucine is: * 1 point None of these Semi-essential Nutritionally essential Nutritionally nonessential 26. Which of the following is a common nitrogen accepting for all reaction 1 point involving transaminase ? * -keto glutarate Pyruvate Oxaloacetate Acetoacetate 27. In a 55 year old man, who has been diagnosed with cirrhosis of liver , 1 point Amonia is not getting detoxified and can damage brain. Which of the following amino acid can covalently bind ammonia, transport and store in a non toxic form? * Glutamate Aspartate Serine Cystatine https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 9/20 7/17/2021 Final exam of Biochemistry (copy A) 28. Which of the following amino acids is not converted to Succinyle Co A? 1 point * Valine Isoleucine None of these Methionine 29. Which of the following amino acids is not required for creatine 1 point synthesis? * Serine Methionine Arginine Glycine 30. Urea is synthesized in : * 1 point Mitochondria Cytoplasm Both cytoplasm and mitochondria In lysosomes https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 10/20 7/17/2021 Final exam of Biochemistry (copy A) 31. Bilirubin in hepatocyte found as a form of: * 1 point Bilirubin diglucurinoid Free bilirubin None of these Bilirubin conjugated with albumin 32.Oxaloacetate forms from : * 1 point Glutamine Aspartate Glutamate Alanine 33. The precursor of serotonin: * 1 point Tryptophan Serine Glycine Histidine https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 11/20 7/17/2021 Final exam of Biochemistry (copy A) 34.Negative nitrogen balance is seen in all of the following conditions 1 point except: * kwashiorkor, and marasmus. advanced cancer Pregnancy Surgery 35.In liver, the bilirubin conjugation process : * 1 point Produce energy Net energy equal zero None of these Consume energy 36.In deamination, amino acid is converted into * 1 point carboxylic acid keto acid aldol acid hydrochloric acid https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 12/20 7/17/2021 Final exam of Biochemistry (copy A) 37. Transamination in amino acids is catalyzed by * 1 point phosphetase dehydrogenases hydrogenases aminotransferases 38. The carbon skeleton of methionine inter TCA from: * 1 point Oxaloacetate α–ketoglutarate Fumarate Succinyl-Co A 39. Glycine is: * 1 point Nutritionally nonessential Semi-essential None of these Nutritionally essential https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 13/20 7/17/2021 Final exam of Biochemistry (copy A) 40. During heme synthesis, The dehydration of two molecules of ALA to 1 point form Porphobilinogen catalyze by the enzyme _____________ * PPG oxidase ALA synthetase UPG III Decaroxylase ALA dehydrase 41. Which phase reaction of conjugation in metabolism of xenobiotics: * 1 point not in the reaction at the end of reaction Phase-I reaction phase-II reaction 42.The main purpose of two phase of metabolism of xenobiotics is related 1 point with * increase their polarity catalyze the monooxygenases increase the hydroxylation of Cytochrome P-450 increase the catalyze of Cytochrome P-450 https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 14/20 7/17/2021 Final exam of Biochemistry (copy A) 43. Example of metabolize is the same xenobiotics? * 1 point Biliverdin Myoglobin Bilirubin anticoagulant warfarin 44. The removing of –OH from phase I reaction in metabolism of 1 point xenobiotics is called: * acytelation hydroxylation functionalization reduction 45. Phase I reaction in metabolism of xenobiotics are catalyzed by: * 1 point all of these Cytochrome P-450 monooxygenases isoforms of cytochrome P450 https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 15/20 7/17/2021 Final exam of Biochemistry (copy A) 46. The reaction in the molecular functional group that present in drug is 1 point going through a: * none of these phase-II reaction Phase-I reaction at the end of reaction 47. What is minifying of xenobiotic metabolism? * 1 point liver then kidneys liver then skin liver then intestine liver then adrenals 48. Which proteins that have function in oxidase system and localized in 1 point the endoplasmic reticulum? * heme, flavoprotein and phosphatidylcholine heme, retinal and phosphatidylcholine heme, flavoprotein and retinal retinal, flavoprotein and phosphatidylcholine https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 16/20 7/17/2021 Final exam of Biochemistry (copy A) 49. The following reactions is a Phase I metabolic of xenobiotic except? 1 point reduction of OH conjugation to OH oxidation of CH3 hydrolysis of CH 3−COO−CH 2−CH 3 Clear selection 50. The hormone that rise the uptake of glucose in skeletal muscle is------- 1 point ------- * Cortisol Epinephrine Insulin Glucagon 51. The fatty liver is occur because of------------- * 1 point absorption a lot of alcohol virus absorption a lot of tobacco absorption a lot of fat https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 17/20 7/17/2021 Final exam of Biochemistry (copy A) 52. The major metabolites of alcohol are ------------- * 1 point Acetyl-CoA Acetaldehyde Pyruvate Catalyze 53. The enzyme that catalyze ethanol to acetaldehyde is--------- * 1 point alcohol dehydrogenase catalase cytochrome P450 2E1 all of these 54. The molecules that regulates the pyruvate kinase is -------------- * 1 point citrate acetyl CoA alanine fructose-1,6-bisphosphate 55. The enzyme that inhibition by fatty acid is---------------- * 1 point h h f ki https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 18/20 7/17/2021 Final exam of Biochemistry (copy A) Phosphofructokinase Pyruvate kinase Glucokinase Hexokinase 56. ATP net production to conversed glucose to pyruvate is---------------- 1 point * 2 ATP+1 GTP 2 ATP 1 ATP +1 GTP 1 ATP 57. Glycolysis occurs in -------------- * 1 point aerobic and anaerobic organisms aerobic organisms neither aerobic or anaerobic organisms anaerobic organisms 58. The molecular that oxidized the following reaction is Pyruvate + 1 point Nicotinamide adenine dinucleotide dehydrogenase + H+ ⇋ lactate + Nicotinamide adenine dinucleotide * pyruvate Nicotinamide adenine dinucleotide Nicotinamide adenine dinucleotide dehydrogenase Nicotinamide adenine dinucleotide dehydrogenase and pyruvate https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 19/20 7/17/2021 Final exam of Biochemistry (copy A) 59. The activity of phosphofructokinase is decreased when --------supply 1 point the ATP supply, * reduced ATP none of these. reduced glucokinase reduced hexokinase 60. Drinking of ethanol cause the unbalance in the ratio of: * 1 point NADH: NAD+ NAD+: NADH FADH2: FAD FAD: FADH2 Page 3 of 3 Back Submit Never submit passwords through Google Forms. This form was created inside of Mustansiriyah University. Report Abuse Forms https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 20/20 7/17/2021 Final exam of Biochemistry (copy A) Final exam of Biochemistry (copy A) The name, username and photo associated with your Google account will be recorded when you upload files and submit this form. Not [email protected]? Switch account * Required Answer the following questions * 40 points Add file This is a required question Page 2 of 3 Back Next https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 1/2 7/17/2021 Final exam of Biochemistry (copy A) Never submit passwords through Google Forms. This form was created inside of Mustansiriyah University. Report Abuse Forms https://docs.google.com/forms/d/e/1FAIpQLSdeImXKVrWZ8wQbdDb-EmttwdPlPtRs3b9BkMQB3HXETnXvtQ/formResponse 2/2