Blood And Circulatory System - Ton Duc Thang University (PDF)

TON DUC THANG UNIVERSITY FACULTY OF APPLIED SCIENCES CHAPTER 1. BLOOD AND CIRCULATORY SYSTEM 21/12/2024 603087-Chapter 1 1  CONTENT 1.1 Blood 1.2 Blood group 1.3 Circulatory system 21/12/2024 603087-Chapter 1 2 ...

TON DUC THANG UNIVERSITY FACULTY OF APPLIED SCIENCES CHAPTER 1. BLOOD AND CIRCULATORY SYSTEM 21/12/2024 603087-Chapter 1 1  CONTENT 1.1 Blood 1.2 Blood group 1.3 Circulatory system 21/12/2024 603087-Chapter 1 2  1.1. Blood - In human adults: approximately 5L - Functions - Composition 21/12/2024 603087-Chapter 1 3  Where are blood cells produced? 21/12/2024 603087-Chapter 1 4 21/12/2024 603087-Chapter 1 5  a. Plasma - Plasma makes up 55%, others 45%. - Three plasma proteins: albumin, globulin, fibrinogen. 21/12/2024 603087-Chapter 1 6 - Metabolism in liver: Albumin: 60% Globulin: 35% Fibrinogen: 5% 21/12/2024 603087-Chapter 1 7  Others: Glucose Lipid Organic acids: lactic acid, citric acid, pyruvic acid, etc. Ketone body 21/12/2024 603087-Chapter 1 8  Plasma vs Serum + Plasma +Serum 21/12/2024 603087-Chapter 1 9  b. Red blood cell - Life span: around 120 days - In men is approximately 4.7 to 6.1 million cells/µl. - In women range from 4.2 to 5.4 million cells/µl. 21/12/2024 603087-Chapter 1 10 21/12/2024 603087-Chapter 1 11 + Structure and component + Function 21/12/2024 603087-Chapter 1 12 21/12/2024 603087-Chapter 1 13 + Abnormal RBC + RBC related diseases/mutations 21/12/2024 603087-Chapter 1 14 21/12/2024 603087-Chapter 1 15 21/12/2024 603087-Chapter 1 16  Bilirubin pathway 21/12/2024 603087-Chapter 1 17 - What is jaundice? - Bilirubin ( conjugated and unconjugated bilirubin) - Color of human feces/ urine 21/12/2024 603087-Chapter 1 18  c. White blood cell - The normal range is 4,500 to 10,000 cells/µl. 21/12/2024 603087-Chapter 1 19 21/12/2024 603087-Chapter 1 20  Eosinophil Decrease when in Stress Increase when in Allergy 21/12/2024 603087-Chapter 1 21  Basophil - Histamin and heparin production 21/12/2024 603087-Chapter 1 22  Lymphocyte - Types of lymphocytes 21/12/2024 603087-Chapter 1 23 + Conclusions: - Macrophage - Phagocytes 21/12/2024 603087-Chapter 1 24  d. Platelet 21/12/2024 603087-Chapter 1 25  A normal platelet count ranges from 150,000 to 450,000 platelets/µl. Function Disorders/diseases 21/12/2024 603087-Chapter 1 26  How are blood clots formed? 21/12/2024 603087-Chapter 1 27 21/12/2024 603087-Chapter 1 28  1.2. Blood group a. ABO system  A,B, AB,O blood group Antigen on the surface of RBC Antibody in the plasma 21/12/2024 603087-Chapter 1 29 21/12/2024 603087-Chapter 1 30 b. Rhesus system  Rh-, Rh+  Antigen on the surface of RBC  Antibody produced only when response to antigen 21/12/2024 603087-Chapter 1 31  Rhesus disease 21/12/2024 603087-Chapter 1 32  Cause  Baby symptoms  Treatment 21/12/2024 603087-Chapter 1 33  Blood transfusion + Blood compatibility rule 21/12/2024 603087-Chapter 1 34 + Principle of blood transfusion +The blood transfusable components: RBC, platelets, fresh frozen plasma. (self - study for more products) 21/12/2024 603087-Chapter 1 35 21/12/2024 603087-Chapter 1 36 - Conclusions:  Blood universal donor  Blood universal recipient + Plasma universal donor + Plasma universal recipient 21/12/2024 603087-Chapter 1 37  1.3. Circulatory system + Open circulatory system + Closed circulatory system 21/12/2024 603087-Chapter 1 38 21/12/2024 603087-Chapter 1 39  Artery: muscular-walled tubes  blood is conveyed from the heart to all parts of the body. Vein: any of the tubes  carrying blood toward the heart Capillary: small blood vessels  between the terminations of the arteries and the beginnings of the veins. 21/12/2024 603087-Chapter 1 40 21/12/2024 603087-Chapter 1 41 - What is valve? 21/12/2024 603087-Chapter 1 42 21/12/2024 603087-Chapter 1 43  Lab tests - Detection/ diagnosis - Tests 21/12/2024 603087-Chapter 1 44  Discussion 1/ Plaque and angioplasty  Stent  By-pass procedure 21/12/2024 603087-Chapter 1 45 2/ Varicose vein 21/12/2024 603087-Chapter 1 46  Overview of evolution of circulatory system in animal - Overview - Conclusion 21/12/2024 603087-Chapter 1 47