Water Soluble Vitamins: Thiamin (Vitamin B1)

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16 Questions

What is the other name for Thiamin?

Vitamin B1

What is the active form of thiamin?

thiamin pyro-P (TDP/TPP)

Where does absorption of thiamin primarily occur?


What is the role of thiaminases in raw fish?

Catalyze the cleavage of thiamin

How is destruction of thiaminase in raw fish prevented?

with the presence of reducing compounds (vit C & citric acid)

Where is most free thiamin taken up following absorption?

by the liver

What is the chief function of thiamin pyrophosphate (TPP)?

Used in energy metabolism

What is the deficiency disease associated with thiamin?


What are the symptoms of thiamin deficiency?

Muscular weakness, apathy, poor short-term memory, confusion, irritability, anorexia, weight loss

What is the neuropsychological complication associated with thiamin deficiency and alcoholism?

Wernicke-Korsakoff syndrome

What are the symptoms of Wernicke-Korsakoff syndrome?

Ophthalmoplegia, nystagmus, ataxia, loss of recent memory, confusion

What are the other names for Riboflavin?

Vitamin B2

What are the chief functions of riboflavin?

Part of coenzymes FMN and FAD used in energy metabolism

What percentage of FAD is covalently bound to either histidine or cysteine in the intestinal lumen?

Approximately 7%

Which sources of B2 are better absorbed: animal or plant sources?

Animal sources

What happens to riboflavin upon absorption into intestinal cells?

Phosphorylated to form FMN

Learn about the functions and stabilities of water soluble vitamins, with a specific focus on thiamin (Vitamin B1). Explore its discovery, structure, and active form, as well as its role as a coenzyme.

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