Immune Responses
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Immune Responses

Created by
@CorgiLover

Questions and Answers

During the primary immune response, what is the first antibody detected in circulation?

IgM

Where does clonal diversity take place?

Thymus

Which cells predominate in early inflammatory responses and ingest bacteria, dead cells, and cellular debris?

Neutrophils

What is the primary role of monocytes and macrophages in the immune response?

<p>Phagocytosis of bacteria</p> Signup and view all the answers

What is the function of T regulatory cells (Tregs) in the immune response?

<p>Regulate the immune response to avoid attacking self</p> Signup and view all the answers

Where do memory T cells reside after being produced?

<p>Secondary lymphoid tissue</p> Signup and view all the answers

What is the role of dendritic cells, macrophages, and B lymphocytes as antigen-processing cells (APCs)?

<p>Process and present antigens to naive lymphocytes</p> Signup and view all the answers

What initiates clonal selection in the immune response?

<p>T and B cells interacting with an antigen</p> Signup and view all the answers

<p>Continues to some degree throughout life</p> Signup and view all the answers

Which type of cells are formed in the blood and act as tissue phagocytic cells?

<p>Macrophages</p> Signup and view all the answers

What is the group of glycoproteins that kill viruses and activate macrophages called?

<p>Interferons</p> Signup and view all the answers

What is the natural antibiotic against bacteria that is produced by macrophages and neutrophils?

<p>Lysozyme</p> Signup and view all the answers

Which fatty acids may be released by damaged cells?

<p>Prostaglandins and leukotrienes</p> Signup and view all the answers

What serum protein stimulates vascular dilation and permeability?

<p>Kinins</p> Signup and view all the answers

Which enzyme precursors undergo cascading chain reaction conversions when activated?

<p>Complement</p> Signup and view all the answers

What is the general term to signify a protein hormone that affects the function of cells lying near the cell of origin?

<p>Cytokine</p> Signup and view all the answers

Which natural barriers are composed of tightly associated epithelial cells?

<p>Skin and mucous membranes</p> Signup and view all the answers

What are the small molecular weight particles secreted by epithelial cells known as?

<p>Antimicrobial peptides</p> Signup and view all the answers

Which types of granulocytes have visible granules and play a role in the immune response?

<p>Basophils</p> Signup and view all the answers

What is the primary role of MHC I?

<p>Present foreign antigens to cytotoxic T cells</p> Signup and view all the answers

What is the main function of IgE?

<p>Provide protection from large parasites</p> Signup and view all the answers

What is the purpose of adaptive (acquired) immunity?

<p>Induce production of antibodies or T cells</p> Signup and view all the answers

Which cell type is responsible for cell-mediated immunity?

<p>T lymphocytes</p> Signup and view all the answers

What is the main characteristic of superantigens (SAGs)?

<p>Activates a large population of T-lymphocytes regardless of antigen specificity</p> Signup and view all the answers

Which antibody class is primarily found in body secretions and dominates the mucosal immune system?

<p>IgA</p> Signup and view all the answers

What is the main function of B lymphocytes?

<p>Produce immunoglobulins (antibodies) by activating B cells and creating plasma cells</p> Signup and view all the answers

What is the primary role of Major Histocompatibility Complex (MHC) II?

<p>Present foreign antigens to T helper cells</p> Signup and view all the answers

What are the components of adaptive (acquired) immunity?

<p>Both B lymphocytes and T lymphocytes</p> Signup and view all the answers

What is the main purpose of nonspecific inflammatory response?

<p>Prevent and limit infection and further damage</p> Signup and view all the answers

Which system forms a fibrinous meshwork at an injured or inflamed site?

<p>Coagulation (clotting) system</p> Signup and view all the answers

What is the primary function of the kinin system?

<p>Activating and assisting inflammatory cells</p> Signup and view all the answers

Which plasma protein system can destroy pathogens directly and activates or collaborates with every other component of the inflammatory response?

<p>Complement system</p> Signup and view all the answers

What are mast cells cellular bags of, located in loose connective tissues close to blood vessels?

<p>Histamine and chemotaxic factor</p> Signup and view all the answers

What is the main effect of histamine on blood vessels?

<p>Dilation of large blood vessels</p> Signup and view all the answers

What is the main substance of the coagulation (clotting) system's fibrinous meshwork at an injured or inflamed site?

<p>Fibrin</p> Signup and view all the answers

Which plasma protein system functions to keep microorganisms and foreign bodies at the site of greatest inflammatory cell activity?

<p>Coagulation (clotting) system</p> Signup and view all the answers

What causes dilation of blood vessels, pain, smooth muscle contraction, vascular permeability, and leukocyte chemotaxis?

<p>Prostaglandins</p> Signup and view all the answers

What function does platelet-activating factor serve in relation to endothelial cells?

<p>Inducing endothelial cell retraction to increase vascular permeability</p> Signup and view all the answers

Where is the H1 receptor, which is involved in inducing bronchoconstriction when stimulated, located?

<p>Smooth muscle cells in the bronchi</p> Signup and view all the answers

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