T Cell Effector Function Comparison Quiz

PerfectBowenite avatar
PerfectBowenite
·

Start Quiz

Study Flashcards

18 Questions

What initiates the proliferation of T lymphocytes that recognize antigens?

Binding of IL-2 to its receptor

What is the role of B7 in the activation of T cells by class II MHC Antigen-presenting cells?

Provides a costimulatory signal to T cells

Which protein functions as a costimulatory molecule on antigen-presenting cells to activate CD4+ T cells?

ICAM-1

What is the major T cell integrin involved in binding to antigen-presenting cells?

LFA-1

What happens if a naïve T cell recognizes an antigen without co-stimulation?

Anergy

What is the end result of signal transduction in a T lymphocyte?

Gene transcription

Which molecule binds CD28 on the T cell surface to provide costimulatory signals?

B7 costimulatory proteins

What is the role of ICAM-1 on antigen-presenting cells interacting with CD4+ T cells?

Functions as a costimulatory molecule

What is the mechanism behind the activation of transcription factors after T cell recognition of antigens?

Recruitment of adaptor proteins at antigen recognition site

What happens if dendritic cells cross-present antigens to CD8+ cells?

Activation of CD8+ cytotoxicity

What is the effector function of CD8+ T cells compared to macrophages or CD4+ T cells?

Killing infected cells with microbial antigens in the cytosol

What is the specific effector function of CD4+ Th2 subset cells?

Recruiting eosinophils to destroy helminthic parasites

Which type of T cells recruit and activate other leukocytes to phagocytose and destroy microbes?

CD4+ helper T cells

What is the role of CD8+ T cells in inducing inflammation?

Producing cytokines that recruit leukocytes

Which subset of CD4+ T cells secretes cytokines that recruit leukocytes and activate phagocytes?

Th1 subset

What is the primary function of CD8+ cytotoxic T lymphocytes (CTLs) in the immune response?

Killing infected cells containing microbial proteins in the cytosol

What distinguishes the effector function of CD4+ Th2 subset from other T cell subsets?

Recruiting eosinophils for parasitic defense

Which leukocytes are primarily recruited by CD4+ Th1 and Th17 subsets?

Neutrophils

Test your knowledge on the effector functions of activated CD8+ T cells compared to macrophages and CD4+ T cells. Learn about how different T cell subsets recognize microbial antigens and contribute to immune responses.

Make Your Own Quizzes and Flashcards

Convert your notes into interactive study material.

Get started for free

More Quizzes Like This

Use Quizgecko on...
Browser
Browser