T Cell Effector Function Comparison Quiz

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18 Questions

What initiates the proliferation of T lymphocytes that recognize antigens?

Binding of IL-2 to its receptor

What is the role of B7 in the activation of T cells by class II MHC Antigen-presenting cells?

Provides a costimulatory signal to T cells

Which protein functions as a costimulatory molecule on antigen-presenting cells to activate CD4+ T cells?


What is the major T cell integrin involved in binding to antigen-presenting cells?


What happens if a naïve T cell recognizes an antigen without co-stimulation?


What is the end result of signal transduction in a T lymphocyte?

Gene transcription

Which molecule binds CD28 on the T cell surface to provide costimulatory signals?

B7 costimulatory proteins

What is the role of ICAM-1 on antigen-presenting cells interacting with CD4+ T cells?

Functions as a costimulatory molecule

What is the mechanism behind the activation of transcription factors after T cell recognition of antigens?

Recruitment of adaptor proteins at antigen recognition site

What happens if dendritic cells cross-present antigens to CD8+ cells?

Activation of CD8+ cytotoxicity

What is the effector function of CD8+ T cells compared to macrophages or CD4+ T cells?

Killing infected cells with microbial antigens in the cytosol

What is the specific effector function of CD4+ Th2 subset cells?

Recruiting eosinophils to destroy helminthic parasites

Which type of T cells recruit and activate other leukocytes to phagocytose and destroy microbes?

CD4+ helper T cells

What is the role of CD8+ T cells in inducing inflammation?

Producing cytokines that recruit leukocytes

Which subset of CD4+ T cells secretes cytokines that recruit leukocytes and activate phagocytes?

Th1 subset

What is the primary function of CD8+ cytotoxic T lymphocytes (CTLs) in the immune response?

Killing infected cells containing microbial proteins in the cytosol

What distinguishes the effector function of CD4+ Th2 subset from other T cell subsets?

Recruiting eosinophils for parasitic defense

Which leukocytes are primarily recruited by CD4+ Th1 and Th17 subsets?


Test your knowledge on the effector functions of activated CD8+ T cells compared to macrophages and CD4+ T cells. Learn about how different T cell subsets recognize microbial antigens and contribute to immune responses.

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