Regulation of Gluconeogenesis

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12 Questions

What is the main inhibitory hormone for gluconeogenesis?


How does insulin affect the activity of key gluconeogenic enzymes?

Decreases their activity

Which hormone is the primary stimulatory hormone for promoting gluconeogenesis during fasting?


What effect do glucocorticoids have on gluconeogenesis?

Both stimulate and inhibit

Which enzyme's activity is decreased by insulin to suppress gluconeogenesis?


How does glucagon increase the availability of gluconeogenic precursors?

Stimulates breakdown of glycogen

What effect do metabolites like fructose-2,6-bisphosphate (F2,6BP) and AMP have on gluconeogenesis?

F2,6BP inhibits a key enzyme while AMP inhibits another enzyme

How does limited substrate availability impact gluconeogenesis?

Limited substrates hinder the process of gluconeogenesis

What role does gene expression play in the regulation of gluconeogenesis?

Gene expression influences the transcription of enzymes involved in gluconeogenesis

Which factor can induce the transcription of genes encoding enzymes for gluconeogenesis?


How do hormones like glucagon impact the regulation of gluconeogenesis?

Glucagon induces gene expression for enzymes aiding in gluconeogenesis

What effect do allosteric regulators have on the enzymes in gluconeogenesis?

Allosteric regulators inhibit enzyme activity in specific steps of gluconeogenesis

Explore the intricate regulatory mechanisms that control gluconeogenesis, the process of synthesizing glucose from non-carbohydrate sources. Learn about hormonal regulation, enzymatic control, and the importance of maintaining blood sugar levels. Understand how insulin inhibits gluconeogenesis by reducing gluconeogenic precursors.

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