Gluconeogenesis and Regulation Quiz
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Gluconeogenesis and Regulation Quiz

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@StimulativeMilkyWay

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Questions and Answers

What are the main factors that stimulate Gluconeogenesis?

  • Increased levels of Fructose-2,6- bisphosphate
  • High levels of insulin and glucagon
  • High concentration of lactate, glycerol, and amino acids (correct)
  • High concentration of citrate, ATP, and Acetyl CoA

    • Which compound acts as an allosteric effector for PFK-1 and FBPase-1 enzymes in Gluconeogenesis regulation?

  • AMP
  • NADH
  • Fructose-2,6-bisphosphate (correct)
  • Acetyl CoA

    • What happens to the cellular level of Fructose-2,6-bisphosphate in response to Glucagon?

  • It remains unchanged
  • It increases
  • It converts to ATP
  • It decreases (correct)

    • Which hormone signals the liver to produce more glucose when blood glucose levels decrease?

    <p>Glucagon</p> Signup and view all the answers

    What is the role of insulin in the regulation of Gluconeogenesis?

    <p>Stimulates glycolysis and inhibits Gluconeogenesis</p> Signup and view all the answers

    Which enzyme is inhibited by AMP and ADP but stimulated by citrate and ATP during Gluconeogenesis?

    <p>FBPase</p> Signup and view all the answers

    What inhibits the alpha-KGA dehydrogenase enzyme?

    <p>Succinyl CoA</p> Signup and view all the answers

    Which molecule can inhibit Citrate synthase and IDH in cellular respiration?

    <p>ATP</p> Signup and view all the answers

    In vertebrate muscle, which molecule activates IDH and alpha-KGA dehydrogenase among the given options?

    <p>Ca ions</p> Signup and view all the answers

    Which tissues primarily depend on glucose for their energy needs?

    <p>Brain and RBC</p> Signup and view all the answers

    What is the process of synthesizing glucose from non-carbohydrate precursors called?

    <p>Gluconeogenesis</p> Signup and view all the answers

    Which organ is responsible for about 90% of Gluconeogenesis in the body?

    <p>Liver</p> Signup and view all the answers

    What is the compartment where gluconeogenesis mainly occurs?

    <p>Cytoplasm</p> Signup and view all the answers

    How many ATP molecules are needed for the synthesis of one glucose from 2 pyruvate or lactate?

    <p>6 ATP</p> Signup and view all the answers

    Which set of reactions in gluconeogenesis are the reverse of glycolysis?

    <p>Only 7 reactions</p> Signup and view all the answers

    Which enzyme converts Fructose-1,6-bisphosphate to Fructose-6-phosphate in gluconeogenesis?

    <p>Fructose-1,6-bisphosphatase</p> Signup and view all the answers

    Which mitochondrial enzyme converts pyruvate to oxaloacetate in the first step of gluconeogenesis?

    <p>Pyruvate carboxylase</p> Signup and view all the answers

    Where does pyruvate arise before being transported to the mitochondria during gluconeogenesis?

    <p>Cytoplasm</p> Signup and view all the answers

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