PCT 202: Properties of Solid Systems - Introduction and Particle Size

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18 Questions

What is the advantage of oral solid dosage forms over injectable dosage forms?

They provide ease and convenience of administration

Which method is not used for particle size determination in solid systems?

X-Ray Diffraction

Which type of solid dosage form is known for offering microbial stability without the need for preservatives?

Tablets

What is a common type of large dose oral powder dosage form?

Dusting powder

Which of the following is NOT a type of solid dosage form discussed in the text?

Lozenges

What is a key reason why powdered drugs are rarely used today?

They lack microbial stability

What type of tablets are designed to release their contents gradually over an extended period of time?

Sustained-release tablets

Which type of tablets are designed to dissolve quickly in the mouth without the need for water?

Mouth dissolving tablets

What is the property of a particle that makes it difficult to assign a meaningful diameter?

Asymmetric shape

Which method of determining particle size involves expressing the diameter in terms of weights, volumes, or surface areas?

Surface area

Which type of capsules are made from a flexible, gel-like material?

Soft gelatin capsules

What is the purpose of enteric-coated tablets?

To resist disintegration in the stomach and dissolve in the intestines

Why is it important to have a good knowledge and control of the particle size of a drug in pharmacy?

To affect the rate of release of the drug from different dosage forms

How does particle size influence the formulation of tablets and capsules?

It is crucial for achieving proper flow properties and mixing of granules

In what way can small particles in a suspension affect its usability?

Small particles settle rapidly, making re-dispersion challenging

What is the significance of particle size in mixtures of solids?

Particle size affects the mixing of solid substances

What are the two important properties in a polydisperse sample of particles?

Shape and surface area of individual particles

How does particle size affect the release of a drug from dosage forms?

Optimal particle size can regulate the rate of drug release

Learn about solid dosage forms and their importance in pharmaceuticals. Explore topics such as particle size, mean particle size, particle size distribution, distribution curves, and methods of particle size determination.

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