Neutrophils and Macrophages in Infection Defense

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Which type of white blood cells are formed partially in the bone marrow?

Granulocytes

What is the primary function of white blood cells in preventing disease?

Destroying invading bacteria or viruses by phagocytosis

Where are lymphocytes and plasma cells partially formed?

Lymph tissue

What is the total number of white blood cells an adult human has per microliter of blood cell?

4,000 - 11,000

Which type of WBC has the shortest life span circulating in the blood before wandering through the capillary membranes into the tissues?

Monocytes

What is the main function of granulocytes and monocytes in protecting the body against invading organisms?

Releasing antimicrobial or inflammatory substances

Which body fluid contains the enzyme pepsin and has a low pH due to the presence of hydrochloric acid?

Gastric juice

What is the function of the enzyme lysozyme found in tears?

Destroys certain bacteria

What is the role of interferons in response to viruses or tumor cells?

Block the replication of viruses

What is the process by which neutrophils and monocytes can squeeze through gaps between the endothelial cells of the blood capillaries and postcapillary venules?

Diapedesis

What is the selective procedure that increases the likelihood of phagocytosis by neutrophils and macrophages?

Roughness of the particle surface

What characteristic is especially important for neutrophils and macrophages in killing bacteria, even when the lysosomal enzymes fail to digest them?

Production of powerful oxidizing agents

What is the main function of myeloperoxidase?

Converts hydrogen peroxide and chloride ions to hypochlorite

What is the role of eosinophils in allergic reactions?

Detoxify inflammation-inducing substances and phagocytize allergen-antibody complexes

Which substances are released by mast cells and basophils during allergic reactions?

Histamine, bradykinin, serotonin, heparin, and several lysosomal enzymes

Test your knowledge about the role of neutrophils and tissue macrophages in defending the body against infections. Understand the functions of these immune cells and how they combat invading bacteria, viruses, and harmful agents.

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