Management of Constipation: Physical Purgatives I

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EnviousHeisenberg
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Which type of purgative retains water in the bowel and stimulates peristalsis by releasing cholecystokinin?

Non-absorbable osmotic salts

Which condition can be managed using lactulose as an osmotic laxative?

Constipation

What is the main mechanism of action of lactulose as an osmotic laxative?

Forms soft stool by reducing pH of the colon

What is the main disadvantage of using liquid paraffin (paraffin oil) as a lubricant purgative?

Can cause leakage from the anal sphincter

How do non-absorbable osmotic salts act as purgatives?

By retaining water in the bowel

Which substance is formed by lactulose when split by colon bacteria, leading to a reduction in pH of the colon?

Lactic acid

What is the primary purpose of using bulk forming purgatives?

To add bulk to the stool

What is the primary use of saline purgatives such as magnesium sulfate (Epsom's salt)?

Retaining water in the bowel

Which outcome is associated with a reduction in pH of the colon due to lactulose administration?

Decreased formation of ammonia

What is one of the disadvantages of using liquid paraffin (paraffin oil) as a lubricant purgative?

Decreases absorption of fat-soluble vitamins

Which of the following is NOT a primary use of lactulose as an osmotic laxative?

Prevention of lipid pneumonia

What is the main disadvantage of using magnesium sulfate (Epsom's salt) as a saline purgative?

None of the above

Which substance is formed by lactulose when split by colon bacteria, leading to a reduction in pH of the colon?

Lactic acid

How does liquid paraffin (paraffin oil) act as a lubricant purgative?

Softens and lubricates hard fecal mass and mucosa of the large intestine

What is the primary mechanism of action of non-absorbable osmotic salts as purgatives?

Retaining water in the bowel

In which condition is lactulose commonly used as an osmotic laxative?

Hepatic encephalopathy (Hepatic coma)

What outcome is associated with a reduction in pH of the colon due to lactulose administration?

Decreased production of ammonia

This quiz covers the use of physical purgatives for managing constipation, including bulk forming purgatives like saline purgatives (e.g., MgSO4, Epsom's salt) and non-absorbable osmotic salts. It also includes the mechanisms of action for substances like lactulose as an osmotic laxative.

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