Innate Immunity Details Quiz

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10 Questions

Which of the following best describes one of the physical barriers of innate immunity?

Presence of intraepithelial lymphocytes

What is the main function of lysozyme in innate immunity?

Breaks down peptidoglycan in bacteria

Which protein effector found in skin and mucosal secretions is involved in the innate immune response?

Antimicrobial peptides (defensins & cathelicidins)

How do neutrophils and macrophages kill bacteria within the phagolysosome?

Via the oxidative burst involving oxygen and nitrogen radicals

What is the role of an activated macrophage in the innate immune response?

Recognition of non-self through PAMPs and other structures

What is the function of Interleukin-8 (IL-8) in the immune response?

Attraction/activation of neutrophils

Which molecule is responsible for activating NK cells and influencing lymphocyte differentiation?

Interleukin-12 (IL-12)

What is the primary function of Tumor necrosis factor-α (TNF-α) in the immune response?

Increased permeability of vascular endothelium

In the context of non-specific phagocytic cells recognizing foreign tissue, what is the role of PRR (Pattern Recognition Receptor)?

To recognize the foreignness of objects in a general way

What is the significance of non-specific phagocytic cells wandering through the body?

They randomly come in contact with foreign tissue

Test your knowledge about the details of innate immunity, including innate barriers and physical barriers. Learn about the characteristics of innate immunity and the specific components of physical barriers according to Kuby Immunology 7th ed., 2013 and Abbas: Cellular and Molecular Immunology, 2018.

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