Questions and Answers
What is the primary site where Type I oxidative deamination occurs?
Liver & Kidney (Mitochondria)
Which molecule is produced as a result of Type I oxidative deamination of Glutamate?
-ketoglutarate
How is L-Glutamate dehydrogenase regulated in terms of energy levels?
Allosterically inhibited by low energy (ADP)
What drives the reaction towards Glutamate synthesis in Type I oxidative deamination?
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Which amino acid undergoes rapid oxidative deamination due to its central role in nitrogen metabolism?
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What type of reaction is Type II oxidative deamination, in terms of reversibility?
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What is the function of mitochondrial glutamine synthetase in the body?
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Which enzyme releases ammonia from glutamine in the mitochondria?
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What role does liver-type glutaminase play in response to high protein intake?
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How is glutamine synthesized in the process involving ATP and ADP?
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What outcome results from a rare deficiency in neonate glutamine synthetase?
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Which enzyme is analogized to glutaminase for a similar reaction catalyzed by L-Asparaginase?
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What is the process of removal of an amino group in the form of free ammonia known as?
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Which type of deamination involves oxidation by removal of hydrogen?
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Which enzyme catalyzes Type I Oxidative Deamination using glutamate as a substrate?
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In Type I Oxidative Deamination, what coenzyme can Glutamate Dehydrogenase use for the deamination reaction?
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What is the source of nitrogen in hepatic urea synthesis provided by the process of deamination?
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Why is NAD+ used in oxidative deamination and NADPH used in reductive amination?
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