Antibodies vs Cell Mediated Immunity

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Which type of immunity is especially important to defend against intracellular organisms that can survive and replicate inside cells?

Cell-Mediated Immunity

What is the primary function of secreted antibodies in humoral immunity?

Defending against extracellular microbes by preventing them from invading tissue cells

Which type of immunity enables the immune system to respond to a large variety of antigens?


What type of immunity is induced in an individual by infection or vaccination?

Active Immunity

What is the difference between passive immunity and active immunity?

Passive immunity is conferred by transfer of antibodies or lymphocytes from an actively immunized individual, while active immunity is induced in an individual by infection or vaccination.

What is the clonal selection hypothesis?

A hypothesis explaining how antigens activate B cells to produce antibodies specific to the antigen.

What does the clonal selection hypothesis predict?

Clones of lymphocytes specific for different antigens develop before encountering the antigens

What is the importance of the lymphocyte repertoire in the adaptive immune system?

It enables specificity, versatility, adaptability, and memory

What does specificity refer to in the context of the adaptive immune system?

The ability to distinguish millions of different antigens or portions of antigens

What is meant by the term 'lymphocyte repertoire'?

The total collection of lymphocyte specificities, which is extremely diverse

What does the clonal selection hypothesis propose about antigen elicitation of an immune response?

It selects and activates the lymphocytes of a specific clone

What does the lymphocyte repertoire enable the adaptive immune system to do?

Effectively recognize, respond to, and remember a wide array of antigens

What is the capability of the adaptive immune system with regards to distinguishing different antigens?

It is capable of distinguishing millions of different antigens or portions of antigens

Explore the differences between secreted antibodies and cell mediated immunity in humoral and cell mediated immune responses. Learn how antibodies defend against microbes in circulation and tissue fluids, while CMI provides defense against intracellular microbes.

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