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IgE Antibodies and Mast Cell Sensitization

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IgE Antibodies and Mast Cell Sensitization

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Questions and Answers

Which of the following is true about the binding of IgE antibody to mast cells?

The binding occurs in atopic individuals only (correct)

The binding occurs in normal individuals only

The binding occurs in all individuals

The binding occurs in individuals with immediate hypersensitivity reactions

What is the role of sensitization in mast cells?

It coats mast cells with IgE antibody in normal individuals

It prevents mast cells from releasing histamine

It makes mast cells sensitive to activation by subsequent encounters with the same antigen (correct)

It activates mast cells in all tissues

Which of the following is true about the FcεRI receptor for IgE?

It has a Kd of approximately 10−9 M

It binds the Fc portion of the γ heavy chain

It is present on mast cells of all individuals (correct)

It consists of two polypeptide chains

Which cells have many of the features of mast cells, but are normally present in low numbers in the blood and not present in tissues?

Basophils Signup and view all the answers

What triggers mast cell activation and the release of inflammatory mediators?

Binding of the allergen to IgE antibodies Signup and view all the answers

Which of the following is NOT a major mediator produced by mast cells?

Interferons Signup and view all the answers

Which cells are involved in the late-phase reaction of immediate hypersensitivity?

Eosinophils, neutrophils, and Th2 cells Signup and view all the answers

IgE Antibodies and Mast Cell Sensitization

Choose a study mode

Podcast

Questions and Answers

Which of the following is true about the binding of IgE antibody to mast cells?

What is the role of sensitization in mast cells?

Which of the following is true about the FcεRI receptor for IgE?

Which cells have many of the features of mast cells, but are normally present in low numbers in the blood and not present in tissues?

What triggers mast cell activation and the release of inflammatory mediators?

Which of the following is NOT a major mediator produced by mast cells?

Which cells are involved in the late-phase reaction of immediate hypersensitivity?

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