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Questions and Answers
Which of the following is true about the binding of IgE antibody to mast cells?
Which of the following is true about the binding of IgE antibody to mast cells?
- The binding occurs in atopic individuals only (correct)
- The binding occurs in normal individuals only
- The binding occurs in all individuals
- The binding occurs in individuals with immediate hypersensitivity reactions
What is the role of sensitization in mast cells?
What is the role of sensitization in mast cells?
- It coats mast cells with IgE antibody in normal individuals
- It prevents mast cells from releasing histamine
- It makes mast cells sensitive to activation by subsequent encounters with the same antigen (correct)
- It activates mast cells in all tissues
Which of the following is true about the FcεRI receptor for IgE?
Which of the following is true about the FcεRI receptor for IgE?
- It has a Kd of approximately 10−9 M
- It binds the Fc portion of the γ heavy chain
- It is present on mast cells of all individuals (correct)
- It consists of two polypeptide chains
Which cells have many of the features of mast cells, but are normally present in low numbers in the blood and not present in tissues?
Which cells have many of the features of mast cells, but are normally present in low numbers in the blood and not present in tissues?
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What triggers mast cell activation and the release of inflammatory mediators?
What triggers mast cell activation and the release of inflammatory mediators?
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Which of the following is NOT a major mediator produced by mast cells?
Which of the following is NOT a major mediator produced by mast cells?
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Which cells are involved in the late-phase reaction of immediate hypersensitivity?
Which cells are involved in the late-phase reaction of immediate hypersensitivity?
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