Anti-Muscarinic and Anti-Serotonin Drugs Quiz

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30 Questions

Which category of drugs increases upper GIT motility and gastric emptying?

Prokinetic drugs

What is the mechanism of action of Macrolide antibiotics (Erythromycin) in increasing gastric motility?

Stimulating motilin receptors

Which drug is used for treating conditions like Gastroesophageal reflux (GERD) and Gastroparesis?


What is the main cause of vomiting according to the text?

Stress-induced dopamine release

Which class of drugs is responsible for acting on the chemoreceptor trigger zone (CTZ) to prevent vomiting?

Antiemetic agents

Which drug category is used for decreasing GIT motility?

Antispasmodic drugs

What is the main effect of blocking dopamine receptors in the chemoreceptor trigger zone of the medulla?

Prokinetic action

Which adverse effect is commonly associated with anti-dopamine drugs?


What distinguishes Domperidone from Metoclopramide in terms of extrapyramidal effects?

Domperidone has no extrapyramidal effects

Which drug is more likely to induce hyperprolactinemia due to D2 blockade in the pituitary gland?


Which anti-dopamine drug does not pass the blood-brain barrier (BBB)?


What is a significant adverse effect of Metoclopramide that is not associated with Domperidone?

Extrapyramidal effects

What is the mechanism of action of osmotic laxatives?

Increase osmotic pressure to draw water into the intestinal lumen

When should stimulant laxatives be used according to the text?

Short-term treatment of constipation

Which condition can overuse of osmotic laxatives lead to?

Metabolic alkalosis

What is the main side effect associated with stimulant laxatives?

Diarrhea and dehydration

What is the role of fecal softeners according to the text?

To soften stool for easier passage through the intestinal tract

What is the main indication for using osmotic laxatives as mentioned in the text?

To treat opioid-induced constipation

What is the mechanism of action of anti-muscarinic drugs like hyoscine (scopolamine)?

They compete with acetylcholine at muscarinic receptors in the gut and CNS

What is the main indication for using anti-histaminic drugs like diphenhydramine?

Relief of allergic rhinitis and allergic reactions

What is the mechanism of action of anti-serotonin drugs like ondansetron?

Blocking 5-HT3 receptors in the GIT and CTZ center

What are the side effects commonly associated with anti-serotonin drugs?

Drowsiness and constipation

Which type of drugs are used to treat motion sickness, vestibulocochlear disease, and hyperemesis gravidarum?

Anti-histaminic drugs

What is the role of prokinetics (motility stimulants) like domperidone in managing constipation?

Stimulating motility in the gut by blocking dopamine D2 receptors

What is the first priority in the treatment of acute diarrhea?

Maintenance of fluid and electrolyte balance

Which drug class acts on opioid receptors in the intestine to decrease peristalsis?

Antimotility agents

In which cases should opiate-like antimotility drugs be avoided?

Active inflammatory bowel disease

What is the mechanism of action of drugs that increase the viscosity of gut contents?

Adsorb water and irritant substances

Which class of drugs are used to treat nausea and vomiting?

Antiemetic drugs

What are the 4 common classes of antiemetic drugs mentioned in the text?

D2 receptor blockers, M receptor blockers, 5-HT3 receptor blockers, H1-receptor blockers

Test your knowledge on anti-muscarinic drugs like Hyoscine (scopolamine) and anti-serotonin drugs like ondansetron. Learn about their mechanisms of action, indications, and side effects.

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