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Histology of Endocrine glands (T&F)

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30 Questions

The thyroid gland is composed of four lobes.

False

The principal cells in the thyroid gland produce thyroid hormones.

False

Graves' disease is a rare autoimmune disease that affects men.

False

Thyroiditis is an acute inflammation of the thyroid gland.

False

Endemic goiter is caused by excessive iodine intake.

False

The parathyroid glands are located within the adrenal glands.

False

The adrenal cortex makes up 15% of the cortical volume.

False

The adrenal medulla produces hormones that regulate water and electrolyte balance.

False

Addison's disease is caused by an overactive adrenal gland.

False

APUD cells are found only in the thyroid gland.

False

The endocrine system excludes the pituitary gland.

False

Hormones are proteins and glycoproteins only.

False

Autocrine communication involves a cell stimulating its neighbor.

False

The pituitary gland is approximately 5 cm in diameter.

False

The adenohypophysis cerebri has only two components.

False

Somatotrophs produce oxytocin.

False

Undersecretion of growth hormone in childhood leads to acromegaly.

False

The pars intermedia is a remnant of Rathe's pouch and mainly consists of active secretory cells.

False

The hypothalamus is a large area in the brain.

False

The infundibulum is a part of the hypothalamus.

False

The hypothalamus is located in the brain, between the pituitary gland and the cerebellum.

False

The hypothalamus plays no role in regulating body temperature.

False

The supraoptic nucleus is a part of the hypothalamus.

True

The pars nervosa contains secretory or neuronal cells.

False

Herring bodies are found in the pars nervosa.

True

The pineal gland weighs approximately 1 kg.

False

Pinealocytes are glial-like cells.

False

The thyroid gland is located in the brain.

False

The hypothalamus is not involved in the regulation of emotions.

False

The hypothalamus is responsible for maintaining homeostasis in the body.

True

Study Notes

Thyroid Gland

  • Built with two lobes connected by a necking
  • Composed of follicles, colloid, blood vessels, and parafollicular cells (C cells)
  • Function: Synthesis of thyroid hormones (T4 and T3)
  • T3: triiodothyronine
  • T4: thyroxine

Thyroid Hormones

  • Produced by principal cells (clear cells)
  • Regulated by parafollicular cells (C cells)

Thyroid Disorders

  • Graves' disease: autoimmune disease, 80-90% of all hyperthyroidism, mostly affects women
  • Thyroiditis: inflammation of the thyroid, mostly chronic-autoimmune, presents as goiter
  • Endemic goiter: enlargement of the thyroid gland due to iodine deficiency in the diet

Parathyroid Gland

  • Composed of oxyphil cells and principal (chief) cells
  • Function: regulates water and electrolyte balance

Adrenal Gland

  • Weight: approximately 18g (adrenal cortex) and 4g (adrenal medulla)
  • Composed of adrenal cortex (95% of the gland) and adrenal medulla (5%)
  • Adrenal cortex: divided into three zones - zona glomerulosa, zona fasciculata, and zona reticularis
  • Function: regulates water and electrolyte balance

Endocrine System

  • Includes endocrine glands and their hormones
  • Function: secretes hormones into the bloodstream to regulate various bodily functions
  • Hormones: chemical messengers that target specific groups of cells to stimulate or inhibit activity

Endocrine Glands

  • Locations: pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pineal gland, and others
  • Hormones: proteins, glycoproteins, small peptides, amino-acid derivatives, and steroids

Communication Pathways

  • Autocrine: cell produces hormone that stimulates or inhibits itself
  • Paracrine: cell produces hormone that stimulates or inhibits its neighbor
  • Juxtacrine: cells sit side by side, one has hormone on its surface, the other has the receptor

Pituitary Gland

  • Weight: approximately 0.5-1g
  • Diameter: approximately 1 cm
  • Components: adenohypophysis (anterior lobe) and neurohypophysis (posterior lobe)

Pituitary Gland Cells

  • Chromophils: acidophils and basophils
  • Chromophobes: non-staining cells
  • Adenohypophysis: produces hormones that regulate various bodily functions
  • Neurohypophysis: stores and releases hormones produced by the hypothalamus

Pituitary Hormones

  • Growth hormone (GH): regulates growth and development
  • Oversecretion: gigantism in childhood and acromegaly in adulthood
  • Undersecretion: dwarfism in childhood

Hypothalamus

  • Weight: approximately 0.7g
  • Diameter: approximately 1 cm
  • Location: center of the brain, between the pituitary gland and thalamus
  • Function: regulates hormone production, body temperature, thirst, appetite, emotions, sleep cycles, sex drive, and other bodily functions
  • Acts as the connector between the endocrine and nervous systems

Pineal Gland

  • Weight: approximately 0.2g
  • Length: 5-8 mm
  • Width: 3-5 mm
  • Composed of pinealocytes, interstitial glial cells, and corpus arenaceum (brain sand)
  • Function: regulates sleep-wake cycles and reproductive hormones

This quiz covers the structure and function of the thyroid gland, including its lobes, neck, and cells, as well as its role in synthesizing thyroid hormones. It also touches on related diseases such as Graves' disease.

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