Sickle Cell Anemia: Molecular Basis of Heredity

Substitution of valine for glutamic acid in the hemoglobin molecule

Periodic sickle cell crises causing severe pain, fever, and swelling of the joints

Genes

<p>Simple units or monomers of nucleic acids</p> Signup and view all the answers

<ol> <li>Nitrogen-containing base, 2) Five-carbon sugar, 3) Phosphoric acid</li> </ol> Signup and view all the answers

<p>Combination of sugar and nitrogenous base</p> Signup and view all the answers

<p>Purines and Pyrimidines</p> Signup and view all the answers

<p>Ribose in RNA and 2-deoxyribose in DNA</p> Signup and view all the answers

<p>It links nucleotides together in the nucleic acid chain.</p> Signup and view all the answers

<p>Phosphoric acid is esterified to the 5’ end of the pentose sugar, resulting in a negatively charged nucleotide.</p> Signup and view all the answers

<ol> <li>The first letter of the base may represent the nitrogenous base. 2) The prefix deoxy- is used to emphasize 2-deoxyribose. 3) Some books use -ic acid to name a nucleotide.</li> </ol> Signup and view all the answers

<p>They proposed a double helix structure consisting of two helical polynucleotide chains coiled around the same axis.</p> Signup and view all the answers

<p>DNA wraps and folds around proteins called histones, allowing for reduction in DNA length.</p> Signup and view all the answers

<p>Adenine bonding with thymine, and guanine bonding with cytosine.</p> Signup and view all the answers

<p>About 2 meters</p> Signup and view all the answers

<p>They determined the structure of DNA.</p> Signup and view all the answers

<p>Substitution of valine for glutamic acid in the hemoglobin molecule</p> Signup and view all the answers

<p>They are the building blocks or monomers of nucleic acids</p> Signup and view all the answers

<p>Genes</p> Signup and view all the answers

<p>Combinations of sugar and nitrogenous base</p> Signup and view all the answers

<p>They determine the sequence of nitrogen-containing bases</p> Signup and view all the answers

<p>Nucleotides joined together, consisting of nitrogen-containing base, five-carbon sugar, and phosphoric acid</p> Signup and view all the answers

<p>Cytosine</p> Signup and view all the answers

<p>Deoxyribose</p> Signup and view all the answers

<p>Phosphoric Acid</p> Signup and view all the answers

<p>Beta Linkage</p> Signup and view all the answers

<p>1', 2', 3'</p> Signup and view all the answers

<p>Double helix</p> Signup and view all the answers

<p>Adenine with thymine</p> Signup and view all the answers