Induced Fit and Ligand Binding

Which molecule binds to hemoglobin and decreases its affinity for oxygen?

What is the effect of carbamylation on hemoglobin?

What is the pH in the tissues where hemoglobin reacts with CO2?

What is the pH in the lungs where HbCO2- is converted to HbO2?

What is the molecule responsible for the resistance of fetal hemoglobin to 2,3-BPG action?

What causes sickle cell anemia?

Which of the following is true about protein function?

What is a molecule bound reversibly by a protein called?

What is a specific site on a protein where a ligand binds called?

What is the term for the reversible binding of ligands to proteins?

In multisubunit proteins, conformational changes in one subunit can affect the others. What is this phenomenon called?

What is the heme prosthetic group in myoglobin and hemoglobin composed of?

Which protein binds carbon monoxide (CO) 20000 times tighter than oxygen (O2)?

Which amino acid in myoglobin does not directly bind to Fe2+ but helps stabilize the O2 binding to Fe2+?

What is the main function of hemoglobin?

Which state of hemoglobin is more stable when O2 is not present?

What is the phenomenon called when the affinity of a protein for O2 varies with local pO2?

How does the pH difference between lungs and metabolic tissues affect the efficiency of O2 transport?

Which type of antibody is the most abundant in the blood?

What is the structure of an IgG antibody?

What is the function of antibodies in the immune response?

What is the mechanism of action of antibodies in the immune response?

Which assay allows the rapid screen and quantification of an antigen in a complex sample?

What is the impact of sickle cell anemia on human health and resistance to malaria?

Which globin protein is responsible for binding oxygen in the muscles?

What is the equation for the fraction of binding sites occupied by a ligand?

What is the equation for the dissociation constant Kd?

What is the significance of the partial pressure of O2 at which 50% of the available binding sites are occupied?

What is the equation for the fraction of binding sites occupied by a ligand when the ligand is a gas expressed in terms of partial pressures?

What is the dissociation constant Kd for the interaction between avidin and biotin?