5 Questions
Which of the following best describes sickle cell anemia?
A group of diseases in which hemoglobin A is partly replaced by abnormal sickle hemoglobin S
Which factor increases the risk of sickle cell anemia?
Having parents heterozygous for hemoglobin S and being of African American descent
What test is frequently used for screening purposes in sickle cell anemia?
Sickle turbidity test (Sickledex)
How does the shape of red blood cells change in sickle cell anemia?
They become larger and elongated
What additional test is necessary to distinguish between sickle cell trait and sickle cell disease if the sickle turbidity test is positive?
Hemoglobin electrophoresis
Study Notes
Sickle Cell Anemia
- Sickle cell anemia is a genetic disorder characterized by the production of abnormal hemoglobin, leading to rigid and sickle-shaped red blood cells.
Risk Factors
- Having a family history of sickle cell anemia increases the risk of developing the disease.
Screening and Diagnosis
- The sickle turbidity test is frequently used for screening purposes in sickle cell anemia.
- If the sickle turbidity test is positive, a hemoglobin electrophoresis test is necessary to distinguish between sickle cell trait and sickle cell disease.
Red Blood Cell Changes
- In sickle cell anemia, the shape of red blood cells changes from the normal disk shape to a sickle or crescent shape due to the abnormal hemoglobin.
Test your knowledge on sickle cell anemia, a group of hemoglobinopathies characterized by the presence of abnormal sickle hemoglobin S. Learn about its causes, risk factors, and screening methods in this informative quiz.
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