Sex Determination and Differentiation (Easy)

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What is the result of a failure to produce testosterone in an XY male?

Undervirilization

What is the effect of 5-alpha-reductase deficiency on testosterone?

Conversion of testosterone to dihydrotestosterone (DHT)

What is the result of androgen receptor deficiency in an XY male?

Complete feminization

What is the cause of testicular feminization in an XY male?

<p>Defective testicular development</p> Signup and view all the answers

What is the term for the condition where an XY male has receptors that do not respond to testosterone?

<p>Testicular feminizing syndrome</p> Signup and view all the answers

What is the genetic makeup of an individual with Turner's Syndrome?

<p>XO</p> Signup and view all the answers

What is the primary effect of the absence of the SRY gene in gonadal development?

<p>Development of ovaries</p> Signup and view all the answers

What is a common physical characteristic of individuals with Turner's Syndrome?

<p>Webbed neck</p> Signup and view all the answers

What is a reproductive consequence of Turner's Syndrome?

<p>Sterility</p> Signup and view all the answers

What is the typical adult height range for individuals with Turner's Syndrome?

<p>Below 5 feet</p> Signup and view all the answers

What is the main reason for male sterility in individuals with a deletion of the PAR1 region in chromosome?

<p>Failure of pairing during meiosis</p> Signup and view all the answers

What is the characteristic feature of an individual with Triple X Syndrome (XXX)?

<p>No sexual abnormalities and possible impairment of intelligence</p> Signup and view all the answers

What is the primary difference between Klinefelter's Syndrome (XXY) and 47:XXY (SRY negative female)?

<p>Absence of SRY gene in 47:XXY</p> Signup and view all the answers

What is the characteristic feature of an individual with XX Male Syndrome?

<p>Male phenotype with XX chromosomes</p> Signup and view all the answers

What is the primary cause of True Hermaphroditism (XX / XY)?

<p>Mixed gonadal dysgenesis</p> Signup and view all the answers

What determines whether the fetus becomes a boy or a girl at fertilization?

<p>Presence of Y chromosome</p> Signup and view all the answers

What is the result of absence of SRY gene in the Y chromosome?

<p>Phenotypic female</p> Signup and view all the answers

What is the name of the syndrome where an individual has XY chromosomes but develops as a female?

<p>XX Male Syndrome</p> Signup and view all the answers

What is the hormone responsible for the regression of the Mullerian duct?

<p>AMH</p> Signup and view all the answers

What is the term for abnormalities in sex determination and differentiation?

<p>Disorders of Sexual Differentiation</p> Signup and view all the answers

What is the genetic sex of Eden Atwood?

<p>XY</p> Signup and view all the answers

What is the condition that Eden Atwood has, which leads to feminization of external male genitalia?

<p>Androgen Insensitivity Syndrome</p> Signup and view all the answers

What is the gonadal sex of Eden Atwood?

<p>Testes</p> Signup and view all the answers

What is the genital sex of Eden Atwood?

<p>Female with no phallus</p> Signup and view all the answers

What is the karyotype of Eden Atwood?

<p>46 XY</p> Signup and view all the answers

What happens to the gonadal development in an XY individual with a deletion of the SRY gene?

<p>Development of ovary</p> Signup and view all the answers

What is the genetic sex of an individual with a translocation of the SRY gene to an X chromosome?

<p>Male (XX)</p> Signup and view all the answers

What is the condition characterized by the presence of ovaries or testes and genitalia of another sex?

<p>Pseudohermaphroditism</p> Signup and view all the answers

What is the result of excess fetal androgens in a genetic female during the 8th to 13th week of gestation?

<p>Female pseudohermaphroditism</p> Signup and view all the answers

What is the condition characterized by ambiguous genitalia in newborn girls due to increased androgen production?

<p>Congenital Adrenal Hyperplasia</p> Signup and view all the answers

What is the genetic sex of an individual with Congenital Adrenal Hyperplasia (CAH)?

<p>XX</p> Signup and view all the answers

What is the type of gonad that develops in the absence of SRY?

<p>Ovary</p> Signup and view all the answers

What is the result of excessive androgen exposure during 8-13 weeks of gestation in an XX female?

<p>Male phallus with a penile urethra and fused scrotum with raphe</p> Signup and view all the answers

What is the term for the condition in which an XX female is over-virilized?

<p>Female pseudohermaphrodite</p> Signup and view all the answers

What is the enzyme deficiency that can cause Congenital Adrenal Hyperplasia (CAH)?

<p>All of the above</p> Signup and view all the answers

What is a possible cause of virilization of an XX female?

<p>Maternal androgen-secreting tumors</p> Signup and view all the answers

What is the typical genitalia of an XX female with Congenital Adrenal Hyperplasia (CAH)?

<p>Internally female, externally ambiguous</p> Signup and view all the answers

What is the result of excessive maternal androgens during fetal development?

<p>Masculinization of an XX female</p> Signup and view all the answers

What is the term for an XX individual with masculinized genitalia?

<p>Female pseudohermaphrodite</p> Signup and view all the answers

During which weeks of gestation is an XX female most sensitive to androgens?

<p>8-13 weeks</p> Signup and view all the answers

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