Penicillin G Acid Sensitivity Reasons
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Questions and Answers

What is the enzyme responsible for the final cross-linking reaction in the cell wall biosynthesis?

Transpeptidase enzyme

What inhibits the final cross-linking reaction in the cell wall, leading to a leaky wall and cell lysis?

Penicillins and cephalosporins

What is the salt concentration like inside the cell compared to outside?

Greater inside the cell

What is the structure of the enzyme that catalyzes the final cross-linking reaction in the cell wall biosynthesis?

<p>Thia zolidine ring</p> Signup and view all the answers

What is the chemical structure of penicillin G?

<p>(2S,5R,6R)-6-acylamino-3,3dimethylpenam-2-carboxylic acid</p> Signup and view all the answers

What is the trivial nomenclature used for penicillins?

<p>Penicillin as suffix and acyl portion (R) as prefix</p> Signup and view all the answers

What is the mechanism by which penicillins and cephalosporins inhibit cell wall biosynthesis?

<p>Inhibiting the final cross-linking reaction</p> Signup and view all the answers

What is the consequence of inhibiting the final cross-linking reaction in the cell wall?

<p>The cell wall becomes leaky</p> Signup and view all the answers

How do penicillins and cephalosporins cause cell lysis?

<p>By allowing water to enter the cell</p> Signup and view all the answers

What is the role of D-alanine and glycine in the final step of cell wall biosynthesis?

<p>Peptide chains are linked together</p> Signup and view all the answers

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