Podcast
Questions and Answers
Penicillin G is not sensitive to acid because of the influence of the acyl chain.
Penicillin G is not sensitive to acid because of the influence of the acyl chain.
False
Penicillin V has better acid stability than penicillin G because of the absence of an electronegative oxygen on the acyl side chain.
Penicillin V has better acid stability than penicillin G because of the absence of an electronegative oxygen on the acyl side chain.
False
Penicillin V is less active than penicillin G because it lacks an electronegative oxygen on the acyl side chain.
Penicillin V is less active than penicillin G because it lacks an electronegative oxygen on the acyl side chain.
False
Ampicillin and oxacillin have better acid stability than penicillin G due to the influence of the acyl chain.
Ampicillin and oxacillin have better acid stability than penicillin G due to the influence of the acyl chain.
Signup and view all the answers
The acyl chain in penicillin V contributes to making it orally administrable.
The acyl chain in penicillin V contributes to making it orally administrable.
Signup and view all the answers
Penicillin G and penicillin V share the same level of allergic sensitivity in individuals.
Penicillin G and penicillin V share the same level of allergic sensitivity in individuals.
Signup and view all the answers
The enzyme responsible for the final cross-linking reaction in the cell wall biosynthesis is known as the transpeptidase enzyme.
The enzyme responsible for the final cross-linking reaction in the cell wall biosynthesis is known as the transpeptidase enzyme.
Signup and view all the answers
Penicillins and cephalosporins inhibit the final cross-linking reaction in the cell wall biosynthesis, causing the cell wall framework to mesh together.
Penicillins and cephalosporins inhibit the final cross-linking reaction in the cell wall biosynthesis, causing the cell wall framework to mesh together.
Signup and view all the answers
The salt concentration inside the cell is lower than those outside the cell, leading to water entering the cell and causing it to shrink.
The salt concentration inside the cell is lower than those outside the cell, leading to water entering the cell and causing it to shrink.
Signup and view all the answers
The acyl chain in penicillins and cephalosporins is influential in inhibiting the final cross-linking reaction of the cell wall biosynthesis.
The acyl chain in penicillins and cephalosporins is influential in inhibiting the final cross-linking reaction of the cell wall biosynthesis.
Signup and view all the answers
Derivatives of 6-aminopenicillanic acid (6-APA) have a trivial nomenclature that uses the acyl portion as suffix and the name penicillin as prefix.
Derivatives of 6-aminopenicillanic acid (6-APA) have a trivial nomenclature that uses the acyl portion as suffix and the name penicillin as prefix.
Signup and view all the answers
Valine is an example of an acyl side chain commonly found in penicillins.
Valine is an example of an acyl side chain commonly found in penicillins.
Signup and view all the answers
The mechanism of action of Penicillins and Cephalosporins involves inhibition of bacterial cell wall synthesis.
The mechanism of action of Penicillins and Cephalosporins involves inhibition of bacterial cell wall synthesis.
Signup and view all the answers
The acyl chain has no influence on the antibacterial action of Penicillins and Cephalosporins.
The acyl chain has no influence on the antibacterial action of Penicillins and Cephalosporins.
Signup and view all the answers
Monobactams contain a β-lactam ring in their structure.
Monobactams contain a β-lactam ring in their structure.
Signup and view all the answers
Clavulanic acid is classified as a Penam-type antibiotic.
Clavulanic acid is classified as a Penam-type antibiotic.
Signup and view all the answers
Antibiotics that belong to the Cephalosporins group do not have a β-lactam ring in their structure.
Antibiotics that belong to the Cephalosporins group do not have a β-lactam ring in their structure.
Signup and view all the answers
The cell wall of bacteria consists of peptidoglycan, which includes only sugar units.
The cell wall of bacteria consists of peptidoglycan, which includes only sugar units.
Signup and view all the answers
