PH 11 Drug Therapy for Mental Health

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Which neurotransmitter is enhanced by benzodiazepines (BNZ) to reduce CNS activity?

GABA

Which of the following is a response to benzodiazepine (BNZ) binding to specific BNZ receptors?

Reduced seizure activity

Which type of drugs have a different chemical structure from benzodiazepines (BNZs) but still bind strongly to BNZ receptors and act in the same ways?

BNZ agonists

Which of the following is a nursing implication for patients taking benzodiazepines (BNZs) for sleep?

Avoid taking sedatives with alcohol

Which class of drugs can reduce anxiety, induce sleep, and relax skeletal muscles depending on drug dose and concentration?

Benzodiazepine agonists

Which drugs are usually a combination of dopamine and serotonin blockers used to reduce positive symptoms and improve negative symptoms of some types of psychosis without causing severe extrapyramidal effects?

Atypical antipsychotics

Which class of drugs affects the neurotransmitters dopamine, norepinephrine, and/or serotonin to help reduce depression?

Atypical antidepressants

Which class of drugs is described as having the ability to reduce anxiety?

Anxiolytics

Which class of drugs inhibits the reuptake of both serotonin and norepinephrine, increasing the concentration of both neurotransmitters available to postsynaptic receptors?

Selective serotonin reuptake inhibitors (SSRIs)

What is the main purpose of sedatives?

Promoting sleep

What is the action of typical antipsychotics?

Blocking dopamine 2 (D2) receptors

What is the role of mood stabilizers in treating bipolar illness?

Reducing symptoms associated with mania and depression

Which of the following is an absolute contraindication for the use of benzodiazepines (BNZs)?

Pregnancy

Which drug is a BNZ receptor antagonist and can be used as an antidote for BNZ overdose?

Flumazenil (Romazicon)

What is the maximum daily dose of lorazepam (Ativan)?

10 mg

What should patients taking buspirone (BuSpar) avoid while on the medication?

Eating grapefruit or drinking grapefruit juice

Which class of drugs can be used as both sedatives and anxiolytics?

BNZs

What is the recommended duration of use for BNZs?

Short-term use

Which drug reduces anxiety without the risk for physical dependence and sedation?

Buspirone

Which category of drugs is commonly used to relieve symptoms of anxiety?

Antidepressants

Which of the following is a possible side effect of BNZs and BNZ agonists when used for anxiety?

Memory loss

What is a potential adverse effect of BNZs and BNZ agonists?

Confusion

Which drug should not be taken with BNZs due to the risk of serious respiratory depression?

Sodium oxybate

Which of the following can significantly increase the blood levels of buspirone?

Grapefruit juice

Which type of drug has a higher risk for addiction and dependency compared to the other?

BNZs

What should be avoided when taking buspirone?

MAOIs

Which neurotransmitter is decreased in depression?

Norepinephrine

Which neurotransmitter is an inhibitory neurotransmitter?

GABA

Which type of drugs are prescribed for sleep?

Benzodiazepines

What are the main purposes of sedatives?

All of the above

Which neurotransmitter is involved in sleep, appetite, pain, mood, learning, movement, motivation and drive, attention, pleasure and reward?

Dopamine

Which neurotransmitter is an inhibitory neurotransmitter involved in sleep, muscle tension, and sedation?

Gamma-Aminobutyric acid (GABA)

Which neurotransmitter is decreased in depression?

Serotonin

Which neurotransmitter is increased in schizophrenia?

Dopamine

Which class of drugs is commonly used to relieve symptoms of anxiety?

Antidepressants

What is the recommended duration of use for benzodiazepines (BNZs)?

Short-term use

Which class of drugs acts with GABA receptors to enhance GABA effects and reduce anxiety?

Benzodiazepines (BNZs)

Which drug reduces anxiety without the risk for physical dependence and sedation?

Buspirone

Which neurotransmitter is enhanced by benzodiazepines (BNZs) and benzodiazepine agonists to reduce anxiety and induce sleep?

GABA

Which of the following is a nursing implication for patients taking benzodiazepines (BNZs) for sleep?

Monitor patient's level of consciousness carefully

Which drug may cause a metallic taste in the mouth?

Eszopiclone

Which of the following is a possible side effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Drowsiness

Which class of drugs inhibits the reuptake of both serotonin and norepinephrine, increasing the concentration of both neurotransmitters available to postsynaptic receptors?

Serotonin norepinephrine reuptake inhibitors (SNRIs)

Which class of drugs is used to reduce depression by interfering with the reuptake of norepinephrine and serotonin?

Tricyclic antidepressants (TCAs)

Which class of drugs partially activates dopamine 2 and 5-HT1A receptors and blocks 5-HT2A receptors, resulting in fewer motor side effects and adverse effects?

Dopamine system stabilizers

Which class of drugs blocks dopamine 2 (D2) receptors in the brain, helping to treat the positive symptoms of psychosis such as hallucinations and delusions?

Typical antipsychotics

Which of the following is a possible side effect of benzodiazepines (BNZs) and BNZ agonists when used for anxiety?

Drowsiness

What are the expected side effects and adverse reactions of benzodiazepines (BNZs) and BNZ agonists?

Drowsiness, memory loss, dizziness

What is the higher risk associated with benzodiazepines (BNZs) compared to BNZ agonists?

Addiction and dependency

Which drug combination can result in serious respiratory depression, even coma?

Benzodiazepines (BNZs) and sodium oxybate

What should be avoided when taking buspirone?

Grapefruit juice

Which neurotransmitter is enhanced by benzodiazepines (BNZs) to reduce central nervous system (CNS) activity?

GABA

Which of the following is a nursing implication for patients taking benzodiazepines (BNZs) for anxiety?

Assess the patient's level of consciousness and ask whether he or she has a history of depression, confusion, falls, and pain.

Which of the following is a lifespan consideration for the use of benzodiazepines (BNZs) and BNZ agonists?

They are not recommended during pregnancy due to the high risk for causing birth defects.

Which of the following drugs is a benzodiazepine agonist approved for anxiety?

Buspirone (BuSpar)

What is the maximum daily dose of lorazepam (Ativan) for anxiety?

10 mg/day

Which class of drugs is commonly used to relieve symptoms of anxiety?

Benzodiazepines (BNZs)

Which neurotransmitter is enhanced by benzodiazepines (BNZ) to reduce CNS activity?

Gamma-aminobutyric acid (GABA)

What is a potential adverse effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Increased anxiety

What is the action of atypical antipsychotic drugs?

Reduce positive symptoms and improve negative symptoms of some types of psychosis without causing severe extrapyramidal effects

Which class of drugs is commonly used to relieve symptoms of anxiety?

Benzodiazepines (BNZs)

What is the action of atypical antipsychotic drugs?

Block dopamine and serotonin receptors

Which neurotransmitter is involved in sleep, appetite, pain, mood, learning, movement, motivation and drive, attention, pleasure and reward?

Serotonin

What is the role of mood stabilizers in treating bipolar illness?

Stabilize mood swings

Which neurotransmitter is decreased in depression?

Serotonin

What is the main purpose of sedatives?

All of the above

Which class of drugs is commonly used to relieve symptoms of anxiety?

Benzodiazepines (BNZs)

Which neurotransmitter is enhanced by benzodiazepines (BNZs) to reduce central nervous system (CNS) activity?

Gamma-Aminobutyric acid (GABA)

Which class of drugs should not be used in older adults due to an increased risk for falls and mortality?

Benzodiazepines (BNZs)

What is the usual dose range for buspirone (BuSpar)?

15-30 mg/day

Which drug interaction can decrease the effectiveness of sedative drugs?

Caffeine

What is the maximum daily dose of lorazepam (Ativan)?

10 mg/day

Which neurotransmitter is enhanced by benzodiazepines (BNZs) to reduce central nervous system (CNS) activity?

GABA

Which of the following is a response to benzodiazepine (BNZ) binding to specific BNZ receptors?

Reduced seizure activity

Which class of drugs blocks dopamine 2 (D2) receptors in the brain, helping to treat the positive symptoms of psychosis such as hallucinations and delusions?

Antipsychotics

Which drug may cause a metallic taste in the mouth?

Eszopiclone

Which class of drugs can be used as anxiolytics and also for sedation?

Benzodiazepines (BNZs)

Which drug is a newer BNZ agonist that can reduce anxiety without the risk of physical dependence and sedation?

Buspirone

Which of the following is a potential adverse effect of long-term use of benzodiazepines (BNZs)?

Physical dependence

Which neurotransmitter is enhanced by benzodiazepines (BNZs) to reduce central nervous system (CNS) activity?

Gamma-aminobutyric acid (GABA)

Which class of drugs partially activates dopamine 2 and 5-HT1A receptors and blocks 5-HT2A receptors, resulting in fewer motor side effects and adverse effects?

Dopamine system stabilizers (DSSs)

What is the main purpose of hypnotics?

Promoting sleep

Which class of drugs inhibits the enzyme monoamine oxidase, resulting in increased availability of certain neurotransmitters and reduction of depressive symptoms?

Monoamine oxidase inhibitors (MAOIs)

What is the main purpose of mood stabilizers?

Treating bipolar illness

Which of the following is a possible side effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Memory loss

Which neurotransmitter is an inhibitory neurotransmitter?

Gamma-aminobutyric acid (GABA)

Which class of drugs can be used as both sedatives and anxiolytics?

Benzodiazepines (BNZs)

Which type of drugs have a different chemical structure from benzodiazepines (BNZs) but still bind strongly to BNZ receptors and act in the same ways?

Benzodiazepine agonists

Which of the following can significantly increase the blood levels of buspirone?

Grapefruit juice

Which neurotransmitter is decreased in depression?

Serotonin

Which neurotransmitter is enhanced by benzodiazepines (BNZs) to reduce central nervous system (CNS) activity?

GABA

Which class of drugs acts with GABA receptors to enhance GABA effects and reduce anxiety?

Benzodiazepines (BNZs)

What is the maximum daily dose of alprazolam (Xanax)?

4 mg

What is the recommended duration of use for benzodiazepines (BNZs)?

Less than 2 to 3 weeks

Which class of drugs is commonly used to relieve symptoms of anxiety?

Benzodiazepines (BNZs)

Which of the following is a potential adverse effect of long-term use of benzodiazepines (BNZs)?

Physical dependence

Which drug is a newer BNZ agonist that can reduce anxiety without the risk of physical dependence and sedation?

Buspirone (Buspar)

Which drug reduces anxiety without the risk for physical dependence and sedation?

Buspirone

Which neurotransmitter is involved in sleep, appetite, pain, mood, learning, movement, motivation and drive, attention, pleasure and reward?

Serotonin

Which neurotransmitter is decreased in depression?

Serotonin

Which class of drugs inhibits the reuptake of both serotonin and norepinephrine, increasing the concentration of both neurotransmitters available to postsynaptic receptors?

Selective serotonin reuptake inhibitors (SSRIs)

Which class of drugs inhibits the enzyme monoamine oxidase, resulting in increased availability of certain neurotransmitters and reduction of depressive symptoms?

Monoamine oxidase inhibitors (MAOIs)

Which class of drugs can reduce anxiety and induce sleep by depressing the central nervous system (CNS)?

Benzodiazepines

What is the main purpose of atypical antipsychotic drugs?

To reduce positive symptoms and improve negative symptoms of some types of psychosis

Which neurotransmitters do atypical antidepressants affect to help reduce depression?

Serotonin and norepinephrine

What is the main purpose of mood stabilizers?

To treat depression and stabilize mood

Which of the following is a potential side effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Physical withdrawal symptoms

Which of the following is an important nursing implication for the use of buspirone (BuSpar) for anxiety?

Avoid driving or operating machinery

Which of the following drugs can significantly increase the action of benzodiazepines (BNZs) and benzodiazepine agonists?

Cimetidine

What is the maximum daily dose of lorazepam (Ativan) for the treatment of anxiety?

10 mg

Which class of drugs inhibits the reuptake of both serotonin and norepinephrine, increasing the concentration of both neurotransmitters available to postsynaptic receptors?

Serotonin norepinephrine reuptake inhibitors (SNRIs)

What is the main purpose of dopamine system stabilizers (DSSs)?

To partially activate dopamine 2 and 5-HT1A receptors and block 5-HT2A receptors

Which class of drugs is used to treat patients with bipolar illness and also has antiseizure properties?

Mood stabilizers

What is the main action of typical antipsychotics?

Block dopamine 2 (D2) receptors in the brain

Which of the following is a potential side effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Drowsiness and memory loss

What is a potential adverse effect of benzodiazepines (BNZs) and benzodiazepine agonists when used for anxiety?

Confusion

Which class of drugs is commonly used to relieve symptoms of anxiety?

Benzodiazepines (BNZs)

What should be avoided when taking buspirone?

Monoamine oxidase inhibitors (MAOIs)

Which drug interaction can decrease the effectiveness of sedative drugs?

Alcohol

What are the expected side effects and adverse reactions of benzodiazepines (BNZs) and benzodiazepine agonists?

Dizziness, headache, hypotension

Test your knowledge on neurotransmitters, drug interactions, and nursing implications related to benzodiazepines. Learn about the effects of benzodiazepine binding to specific receptors, different drugs that interact with these receptors, and their implications in treating various conditions.

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