Podcast
Questions and Answers
What is the main function of Lifitegrast (Xiidra)?
What is the main function of Lifitegrast (Xiidra)?
- Inhibiting the interaction between LFA-1 and ICAM-1 (correct)
- Promoting the formation of immunological synapse
- Facilitating the overexpression of ICAM-1
- Stimulating T-cell activation
Which cell surface protein is found on leukocytes?
Which cell surface protein is found on leukocytes?
- MHC
- LFA-1 (correct)
- TCR
- ICAM-1
What is the role of ICAM-1 in DED corneal and conjunctival tissues?
What is the role of ICAM-1 in DED corneal and conjunctival tissues?
- Facilitating leukocyte adhesion (correct)
- Preventing immunological synapse formation
- Suppressing inflammation
- Activating T-cell receptors
Which molecule can contribute to the formation of immunological synapse resulting in T-cell activation?
Which molecule can contribute to the formation of immunological synapse resulting in T-cell activation?
What is the function of APC in the immune system?
What is the function of APC in the immune system?
What is MHC in the context of immune system?
What is MHC in the context of immune system?
What does TCR stand for in the context of immune system?
What does TCR stand for in the context of immune system?
What is the function of LFA-1 in immune response?
What is the function of LFA-1 in immune response?
What role does Lifitegrast play in the interaction between LFA-1 and ICAM-1?
What role does Lifitegrast play in the interaction between LFA-1 and ICAM-1?
What is the potential effect of chronic use of topical corticosteroids on the eyes?
What is the potential effect of chronic use of topical corticosteroids on the eyes?
What is the author's conclusion about the evidence of using topical steroids for dry eye?
What is the author's conclusion about the evidence of using topical steroids for dry eye?
Based on the implications for practice, how does the use of topical corticosteroids compare to artificial tears for dry eye treatment?
Based on the implications for practice, how does the use of topical corticosteroids compare to artificial tears for dry eye treatment?
What does the evidence support regarding the effects of topical corticosteroids on corneal staining scores?
What does the evidence support regarding the effects of topical corticosteroids on corneal staining scores?
What is uncertain regarding the effects of topical corticosteroids on tear quality or production?
What is uncertain regarding the effects of topical corticosteroids on tear quality or production?
What is one of the potential adverse effects related to the use of topical corticosteroids according to the text?
What is one of the potential adverse effects related to the use of topical corticosteroids according to the text?
What is uncertain about the potential effects of short-term use of topical steroids on intraocular pressure (IOP)?
What is uncertain about the potential effects of short-term use of topical steroids on intraocular pressure (IOP)?
What does the evidence suggest about the effects of using topical corticosteroids compared to cyclosporine A for dry eye treatment?
What does the evidence suggest about the effects of using topical corticosteroids compared to cyclosporine A for dry eye treatment?
What is the expected timeline for significant improvement when using Cyclosporine 0.05% (Restasis) for dry eyes?
What is the expected timeline for significant improvement when using Cyclosporine 0.05% (Restasis) for dry eyes?
Why is it recommended to put the patient on a steroid initially when using Cyclosporine 0.05% (Restasis)?
Why is it recommended to put the patient on a steroid initially when using Cyclosporine 0.05% (Restasis)?
In which conditions is the use of Cyclosporine 0.05% (Restasis) contraindicated?
In which conditions is the use of Cyclosporine 0.05% (Restasis) contraindicated?
What is the desired response on Schirmer 2 to ensure the effectiveness of Cyclosporine 0.05% (Restasis)?
What is the desired response on Schirmer 2 to ensure the effectiveness of Cyclosporine 0.05% (Restasis)?
What is a consideration to keep in mind when prescribing Cyclosporine 0.05% (Restasis) for dry eyes?
What is a consideration to keep in mind when prescribing Cyclosporine 0.05% (Restasis) for dry eyes?
What is the recommended dosage for Cyclosporine 0.05% (Restasis)?
What is the recommended dosage for Cyclosporine 0.05% (Restasis)?
What is the expected maintenance schedule after significant improvement has been achieved with Cyclosporine 0.05% (Restasis)?
What is the expected maintenance schedule after significant improvement has been achieved with Cyclosporine 0.05% (Restasis)?
What is a characteristic of the dosage form of Cyclosporine 0.05% (Restasis)?
What is a characteristic of the dosage form of Cyclosporine 0.05% (Restasis)?
What is Vevye (cyclosporine 0.1% ophthalmic solution) known for in comparison to other cyclosporine formulations?
What is Vevye (cyclosporine 0.1% ophthalmic solution) known for in comparison to other cyclosporine formulations?
Which drug is a Lymphocyte function-associated antigen-1 (LFA-1) antagonist?
Which drug is a Lymphocyte function-associated antigen-1 (LFA-1) antagonist?
What is the specific advantage of using Vevye (cyclosporine 0.1% ophthalmic solution) as miebo?
What is the specific advantage of using Vevye (cyclosporine 0.1% ophthalmic solution) as miebo?
What does most studies say about the effect of the mechanism on T-cells?
What does most studies say about the effect of the mechanism on T-cells?
What is the classification of CyclASol 0.1%?
What is the classification of CyclASol 0.1%?
Which drug was approved for the treatment of signs/symptoms of dry eye disease in July 2016?
Which drug was approved for the treatment of signs/symptoms of dry eye disease in July 2016?
What is the specific dosage recommendation for Lifitegrast (Xiidra 5%)?
What is the specific dosage recommendation for Lifitegrast (Xiidra 5%)?
How does Lifitegrast (Xiidra 5%) interact with the surface of the eye?
How does Lifitegrast (Xiidra 5%) interact with the surface of the eye?
