Podcast
Questions and Answers
Which medication shows improvement in conjunctival staining and subjective measures of dry eye?
Which medication shows improvement in conjunctival staining and subjective measures of dry eye?
- Lifitegrast (Xiidra)
- Cyclosporine 0.09% (CEQUA)
- Cyclosporine 0.05% (Restasis) (correct)
- Artificial tears
What is the most common adverse effect of Cyclosporine 0.05% (Restasis)?
What is the most common adverse effect of Cyclosporine 0.05% (Restasis)?
- Ocular burning (correct)
- Mild ocular hyperemia
- Epiphora
- Blur
What is the indication for Cyclosporine 0.09% (CEQUA)?
What is the indication for Cyclosporine 0.09% (CEQUA)?
- To relieve eye pain
- To treat allergic conjunctivitis
- To reduce ocular hyperemia
- To increase tear production in keratoconjunctivitis sicca (correct)
Which medication has the highest FDA-approved concentration of cyclosporine A for Dry Eye?
Which medication has the highest FDA-approved concentration of cyclosporine A for Dry Eye?
What is the reported adverse effect of CEQUA (cyclosporine ophthalmic solution) 0.09%?
What is the reported adverse effect of CEQUA (cyclosporine ophthalmic solution) 0.09%?
Which medication is known for its improvement in SPK and subjective measures of dry eye?
Which medication is known for its improvement in SPK and subjective measures of dry eye?
What is the global dry eye definition according to TFOS DEWS II?
What is the global dry eye definition according to TFOS DEWS II?
What is the core mechanism of Dry Eye Disease according to the Pathophysiology Report?
What is the core mechanism of Dry Eye Disease according to the Pathophysiology Report?
Which factor damages the ocular surface directly and by initiating inflammation in Dry Eye Disease?
Which factor damages the ocular surface directly and by initiating inflammation in Dry Eye Disease?
According to TFOS DEWS II, what plays etiological roles in dry eye disease?
According to TFOS DEWS II, what plays etiological roles in dry eye disease?
What characterizes dry eye as per the TFOS DEWS II definition?
What characterizes dry eye as per the TFOS DEWS II definition?
What is the role of neurosensory abnormalities in dry eye disease according to TFOS DEWS II?
What is the role of neurosensory abnormalities in dry eye disease according to TFOS DEWS II?
Which of the following is a potential side effect of using Lacrisert?
Which of the following is a potential side effect of using Lacrisert?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What are the potential candidates for lacrimal occlusion therapy?
What are the potential candidates for lacrimal occlusion therapy?
Which type of plugs may result in retention of pro-inflammatory proteins?
Which type of plugs may result in retention of pro-inflammatory proteins?
What is the potential duration for the extended dissolvable synthetic absorbable plug Oasis?
What is the potential duration for the extended dissolvable synthetic absorbable plug Oasis?
Which procedure involves the use of collagen rods that dissolve over 4-7 days?
Which procedure involves the use of collagen rods that dissolve over 4-7 days?
What type of plugs can be removed and have a contraindication of chronic dacryocystitis?
What type of plugs can be removed and have a contraindication of chronic dacryocystitis?
What is the primary function of tear conservation ointments?
What is the primary function of tear conservation ointments?
What is the recommended frequency for using Lacrisert?
What is the recommended frequency for using Lacrisert?
'Freeman plug' and 'Smart Plugs' are associated with which procedure?
'Freeman plug' and 'Smart Plugs' are associated with which procedure?
What is the approximate diameter of collagen rods used in lacrimal occlusive devices?
What is the approximate diameter of collagen rods used in lacrimal occlusive devices?
What is the duration of use for Oasis, an extended duration absorbable plug?
What is the duration of use for Oasis, an extended duration absorbable plug?
What is the most common complication associated with plug loss?
What is the most common complication associated with plug loss?
Which device stimulates the external branch of the anterior ethmoidal nerve to increase tear production?
Which device stimulates the external branch of the anterior ethmoidal nerve to increase tear production?
What is the main adverse event associated with the use of the iTear100 device?
What is the main adverse event associated with the use of the iTear100 device?
What is the exact mechanism of action of TYRVAYA (varenicline solution) nasal spray?
What is the exact mechanism of action of TYRVAYA (varenicline solution) nasal spray?
How should TYRVAYA nasal spray be administered to avoid complications?
How should TYRVAYA nasal spray be administered to avoid complications?
What is the purpose of TYRVAYA nasal spray?
What is the purpose of TYRVAYA nasal spray?
Which drug is a selective nicotinic acetylcholine agonist used in nasal spray form for dry eye disease?
Which drug is a selective nicotinic acetylcholine agonist used in nasal spray form for dry eye disease?
According to the author, what is the overall certainty of evidence regarding the use of topical steroids for dry eye disease?
According to the author, what is the overall certainty of evidence regarding the use of topical steroids for dry eye disease?
Which treatment option avoids painful drop instillation and offers ease of administration?
Which treatment option avoids painful drop instillation and offers ease of administration?
What is the main side effect associated with the use of TYRVAYA nasal spray?
What is the main side effect associated with the use of TYRVAYA nasal spray?
What is the purpose of the iTear100 device?
What is the purpose of the iTear100 device?
Which drug stimulates tear secretion from meibomian glands, lacrimal glands, and goblet cells?
Which drug stimulates tear secretion from meibomian glands, lacrimal glands, and goblet cells?
Artificial tear formulations preserved in bottle break down to nontoxic substances when exposed to light or ocular surface. Which substance breaks down to sodium chloride and water?
Artificial tear formulations preserved in bottle break down to nontoxic substances when exposed to light or ocular surface. Which substance breaks down to sodium chloride and water?
Which preservative in artificial tear formulations may cause epithelial toxicity and tear disruption?
Which preservative in artificial tear formulations may cause epithelial toxicity and tear disruption?
Which nutrient is essential for the differentiation and maintenance of mucosal epithelium, and its absence may lead to the loss of goblet cells?
Which nutrient is essential for the differentiation and maintenance of mucosal epithelium, and its absence may lead to the loss of goblet cells?
Which of the following artificial tear formulations is a hypotonic solution that decreases osmolarity and is preserved with sodium perborate?
Which of the following artificial tear formulations is a hypotonic solution that decreases osmolarity and is preserved with sodium perborate?
Which artificial tear formulation is known for its nano-droplet technology, which helps retain lubricant on the ocular surface?
Which artificial tear formulation is known for its nano-droplet technology, which helps retain lubricant on the ocular surface?
What is the active ingredient in Eyesol® (perfluorohexyloctane based solution) that prevents evaporation of the aqueous layer in tears?
What is the active ingredient in Eyesol® (perfluorohexyloctane based solution) that prevents evaporation of the aqueous layer in tears?
Which ophthalmic solution is 100% perfluorohexyloctane drop, with no water, no preservative, and no other ingredients?
Which ophthalmic solution is 100% perfluorohexyloctane drop, with no water, no preservative, and no other ingredients?
Which preservative free ophthalmic drop is also known as NOV03 and has a dual mode of action that affects abnormalities in the lipid layer and meibomian glands?
Which preservative free ophthalmic drop is also known as NOV03 and has a dual mode of action that affects abnormalities in the lipid layer and meibomian glands?
Which artificial tear formulation interacts with the lipophilic layer of tears to prevent evaporation and has low surface tension for rapid spread over the ocular surface?
Which artificial tear formulation interacts with the lipophilic layer of tears to prevent evaporation and has low surface tension for rapid spread over the ocular surface?
In the SEECASE study, which ophthalmic solution showed benefits for signs and symptoms favoring QID application?
In the SEECASE study, which ophthalmic solution showed benefits for signs and symptoms favoring QID application?
Which artificial tear formulation is known for its proprietary polymer HP-Guar that chemically combines with borate in the pH environment of the eye to create a meshwork gel retaining active lubricants on the ocular surface?
Which artificial tear formulation is known for its proprietary polymer HP-Guar that chemically combines with borate in the pH environment of the eye to create a meshwork gel retaining active lubricants on the ocular surface?
Which of the following is a result of tear hyperosmolarity in dry eye disease?
Which of the following is a result of tear hyperosmolarity in dry eye disease?
In which form of dry eye disease does tear hyperosmolarity result from reduced lacrimal secretion?
In which form of dry eye disease does tear hyperosmolarity result from reduced lacrimal secretion?
What is the main purpose of tear supplementation in dry eye treatment?
What is the main purpose of tear supplementation in dry eye treatment?
What function do polysaccharides serve in artificial tear formulation?
What function do polysaccharides serve in artificial tear formulation?
Which substance is an example of a viscoelastic polysaccharide used in artificial tear formulation?
Which substance is an example of a viscoelastic polysaccharide used in artificial tear formulation?
What do buffers in artificial tear formulation resist?
What do buffers in artificial tear formulation resist?
What is the primary function of tonicity and pH regulators in artificial tear formulation?
What is the primary function of tonicity and pH regulators in artificial tear formulation?
What is the role of electrolytes in artificial tear formulation?
What is the role of electrolytes in artificial tear formulation?
Which type of polymer serves to decrease blink friction and minimize surface tension in artificial tear formulation?
Which type of polymer serves to decrease blink friction and minimize surface tension in artificial tear formulation?
Corticosteroids for dry eye are likely to provide what level of improvement in symptoms compared with artificial tears?
Corticosteroids for dry eye are likely to provide what level of improvement in symptoms compared with artificial tears?
What is the FDA approval status of Cyclosporine 0.09%?
What is the FDA approval status of Cyclosporine 0.09%?
What is the main mechanism of action of Cyclosporine in the eye?
What is the main mechanism of action of Cyclosporine in the eye?
Which adverse reaction is NOT commonly associated with systemic Cyclosporine therapy?
Which adverse reaction is NOT commonly associated with systemic Cyclosporine therapy?
What is the main effect of topical Cyclosporine on T cells?
What is the main effect of topical Cyclosporine on T cells?
Which statement about the penetration of Cyclosporine into the eye is true?
Which statement about the penetration of Cyclosporine into the eye is true?
What is the primary indication for using Cyclosporine 0.05% (Restasis) in patients?
What is the primary indication for using Cyclosporine 0.05% (Restasis) in patients?
In conjunctival biopsies, how does Cyclosporine reduce dry eye symptoms?
In conjunctival biopsies, how does Cyclosporine reduce dry eye symptoms?
At what time period can significant improvement be expected after using Cyclosporine 0.05% (Restasis)?
At what time period can significant improvement be expected after using Cyclosporine 0.05% (Restasis)?
What is the primary function of tear supplementation in dry eye treatment?
What is the primary function of tear supplementation in dry eye treatment?
Which artificial tear formulation interacts with the lipophilic layer of tears to prevent evaporation and has low surface tension for rapid spread over the ocular surface?
Which artificial tear formulation interacts with the lipophilic layer of tears to prevent evaporation and has low surface tension for rapid spread over the ocular surface?
What characterizes dry eye as per the TFOS DEWS II definition?
What characterizes dry eye as per the TFOS DEWS II definition?
What is the purpose of the iTear100 device?
What is the purpose of the iTear100 device?
Which medication has the highest FDA-approved concentration of cyclosporine A for Dry Eye?
Which medication has the highest FDA-approved concentration of cyclosporine A for Dry Eye?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What preservative free ophthalmic drop is also known as NOV03 and has a dual mode of action that affects abnormalities in the lipid layer and meibomian glands?
What preservative free ophthalmic drop is also known as NOV03 and has a dual mode of action that affects abnormalities in the lipid layer and meibomian glands?
'MEIBO' is a perfluorohexyloctane drop that spreads uniformly over the ocular surface, preventing evaporation and sensitizing osmolarity changes. What type of liquid is perfluorohexyloctane?
'MEIBO' is a perfluorohexyloctane drop that spreads uniformly over the ocular surface, preventing evaporation and sensitizing osmolarity changes. What type of liquid is perfluorohexyloctane?
What is the main adverse event associated with the use of the iTear100 device?
What is the main adverse event associated with the use of the iTear100 device?
What is the main effect of topical Cyclosporine on T cells?
What is the main effect of topical Cyclosporine on T cells?
What preservative in artificial tear formulations may cause epithelial toxicity and tear disruption?
What preservative in artificial tear formulations may cause epithelial toxicity and tear disruption?
What is the core mechanism of Dry Eye Disease according to the Pathophysiology Report?
What is the core mechanism of Dry Eye Disease according to the Pathophysiology Report?
What does TFOS DEWS II define dry eye as?
What does TFOS DEWS II define dry eye as?
What is the main mechanism of action of Cyclosporine in the eye?
What is the main mechanism of action of Cyclosporine in the eye?
What role do neurosensory abnormalities play in dry eye disease according to TFOS DEWS II?
What role do neurosensory abnormalities play in dry eye disease according to TFOS DEWS II?
What is the global dry eye definition according to TFOS DEWS II?
What is the global dry eye definition according to TFOS DEWS II?
What plays etiological roles in dry eye disease according to TFOS DEWS II?
What plays etiological roles in dry eye disease according to TFOS DEWS II?
What damages the ocular surface directly and by initiating inflammation in Dry Eye Disease?
What damages the ocular surface directly and by initiating inflammation in Dry Eye Disease?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What is the approximate duration for Lacrisert to dissolve once inserted in the eye?
What are potential candidates for lacrimal occlusion therapy?
What are potential candidates for lacrimal occlusion therapy?
Which medication shows improvement in conjunctival staining and subjective measures of dry eye?
Which medication shows improvement in conjunctival staining and subjective measures of dry eye?
What is the FDA approval status of Cyclosporine 0.09%?
What is the FDA approval status of Cyclosporine 0.09%?
What is the main consequence of tear hyperosmolarity in Dry Eye Disease?
What is the main consequence of tear hyperosmolarity in Dry Eye Disease?
Which form of Dry Eye Disease is characterized by tear hyperosmolarity caused by excessive evaporation from the exposed tear film?
Which form of Dry Eye Disease is characterized by tear hyperosmolarity caused by excessive evaporation from the exposed tear film?
What is the primary function of tear supplementation in dry eye treatment?
What is the primary function of tear supplementation in dry eye treatment?
Which substance functions to enhance viscosity, lubrication, retention time, and tear stability in artificial tear formulation?
Which substance functions to enhance viscosity, lubrication, retention time, and tear stability in artificial tear formulation?
What are examples of viscoelastic substances used as polysaccharides in artificial tear formulation?
What are examples of viscoelastic substances used as polysaccharides in artificial tear formulation?
What do buffers in artificial tear formulation primarily resist?
What do buffers in artificial tear formulation primarily resist?
What is the purpose of tonicity and pH regulators in artificial tear formulation?
What is the purpose of tonicity and pH regulators in artificial tear formulation?
What do electrolytes in artificial tear formulation primarily maintain or lower?
What do electrolytes in artificial tear formulation primarily maintain or lower?
You are designing an ideal artificial tear. What is the main characteristic of the polymer it should contain?
You are designing an ideal artificial tear. What is the main characteristic of the polymer it should contain?
What is the primary role of polysaccharides in artificial tear formulation?
What is the primary role of polysaccharides in artificial tear formulation?
What is the primary function of sodium chloride and boric acid in artificial tear formulation?
What is the primary function of sodium chloride and boric acid in artificial tear formulation?
What effect does sodium hyaluronate (500,000 x viscosity saline) have in artificial tear formulation?
What effect does sodium hyaluronate (500,000 x viscosity saline) have in artificial tear formulation?
