Neuropathic Pain and Nociceptive Pain Types

What is the primary cause of radicular pain?

Irritation of nerve roots

What is visceral pain often described as?

Aching and may have a vague location

Which of the following is NOT a cause of neuropathic pain?

Stimulation of pain receptors in tissues

What is the term for an increase in the perception of pain generated by a stimulus that causes pain?

Hyperalgesia Signup and view all the answers

What is the primary focus of neuropathic pain management?

Treating symptoms and sometimes etiological causes Signup and view all the answers

Which of the following is a symptom of neuropathic pain?

Paresthesia Signup and view all the answers

Which medication is most effective in reducing neuropathic pain?

Duloxetine Signup and view all the answers

What is the mechanism of action of lidocaine patches in reducing neuropathic pain?

Blocking voltage-gated sodium channels Signup and view all the answers

What is the action of capsaicin on the TRPV1 receptor?

Agonism Signup and view all the answers

What is the additional effect of tramadol that contributes to its analgesic properties in neuropathic pain?

Serotonin inhibition and norepinephrine reuptake Signup and view all the answers

What is the common side effect of duloxetine and venlafaxine that necessitates caution in patients with cardiac disease?

Increased blood pressure and cardiac conduction abnormalities Signup and view all the answers

What is the effect of oxycodone and morphine on the sensation of pain?

Increase in tolerance to pain Signup and view all the answers

What is the mechanism of action of Tricyclic Antidepressants in relation to serotonin and noradrenaline?

They inhibit the reuptake of serotonin and noradrenaline Signup and view all the answers

Which of the following conditions is Tricyclic Antidepressants contraindicated in?

Some cardiac conduction disturbances Signup and view all the answers

What is the target of Gabapentin and Pregabalin in the treatment of pain?

The α2-δ subunit of Ca²+ voltage-dependent channels Signup and view all the answers

What is the effect of Gabapentin and Pregabalin on Ca²+ influx to the cells?

Decrease Ca²+ influx Signup and view all the answers

Which of the following is NOT a first-line treatment for painful neuropathy?

Strong opioids Signup and view all the answers

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in relation to serotonin and norepinephrine?

They inhibit the reuptake of serotonin and norepinephrine Signup and view all the answers

What is the primary mechanism of action of Lidocaine patches in reducing neuropathic pain?

Blocking voltage-gated sodium channels Signup and view all the answers

What is the effect of Capsaicin on the sensation of temperature?

It is sensitive to different ranges of temperature Signup and view all the answers

Why should Duloxetine and Venlafaxine be used cautiously in patients with cardiac disease?

Because they can cause cardiac conduction abnormalities Signup and view all the answers

What is the additional mechanism of action of Tramadol that contributes to its analgesic properties in neuropathic pain?

All of the above Signup and view all the answers

What is the primary effect of Oxycodone and Morphine on the sensation of pain?

They decrease the discomfort of pain by increasing tolerance Signup and view all the answers

What is the primary mechanism of action of Capsaicin?

It is a potent receptor agonist of TRPV1 Signup and view all the answers

What is the effect of Amitriptyline on cholinergic, adrenergic, and histaminergic receptors and ionic channels?

Inhibition Signup and view all the answers

What type of pain occurs when pain receptors in tissues are stimulated?

Somatic pain Signup and view all the answers

Which of the following is a cause of neuropathic pain?

Nerve injury due to diabetes Signup and view all the answers

Which of the following medications is used to treat pain following spinal cord injury?

Amitriptyline Signup and view all the answers

What is the binding site of Gabapentin and Pregabalin in the treatment of pain?

α2-δ subunit of Ca²+ voltage-dependent channels Signup and view all the answers

What is the characteristic of visceral pain?

It is often described as aching and has a vague location Signup and view all the answers

What is the focus of neuropathic pain management?

Treating the symptoms of pain Signup and view all the answers

What is the side effect of Gabapentin and Pregabalin that is related to movement?

Ataxia Signup and view all the answers

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in relation to serotonin and norepinephrine?

Inhibition of serotonin and norepinephrine reuptake Signup and view all the answers

What is the term for pain due to a stimulus that does not normally provoke pain?

Allodynia Signup and view all the answers

In which patients are Tricyclic Antidepressants contraindicated?

All of the above Signup and view all the answers

Which of the following is a sign of neuropathic pain?

Pins and needles Signup and view all the answers

What is the result of nerve injury or diseases such as diabetes, shingles, or cancer?

Neuropathic pain Signup and view all the answers

What is the characteristic of pain that occurs when pain receptors in internal organs are stimulated?

It is often described as aching and may have a vague location Signup and view all the answers

What is the focus of neuropathic pain management?

Treating symptoms and occasionally the underlying causes Signup and view all the answers

What is the term for pins and needles sensation?

Paresthesia Signup and view all the answers

What is the result of pain receptors in tissues being stimulated?

Somatic pain Signup and view all the answers

What is the term for an increase in the perception of pain generated by a stimulus that causes pain?

Hyperalgesia Signup and view all the answers

What is the mechanism of action of Tricyclic Antidepressants (TCAs) in terms of serotonin and noradrenaline?

They inhibit the reuptake of serotonin and noradrenaline. Signup and view all the answers

What is the common side effect of Gabapentin and Pregabalin that is related to the central nervous system?

Dizziness Signup and view all the answers

Which of the following medications is used to treat neuropathic pain by binding to the alpha-2 delta subunit of calcium channels?

Gabapentin Signup and view all the answers

What is the contraindication for Tricyclic Antidepressants (TCAs) in terms of cardiac conditions?

Some cardiac conduction disturbances Signup and view all the answers

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in terms of serotonin and noradrenaline?

They inhibit the reuptake of serotonin and noradrenaline. Signup and view all the answers

What is the indication for the use of strong opioids, such as oxycodone and tramadol, in the treatment of neuropathic pain?

Third-line treatment Signup and view all the answers

What is the primary effect of Oxycodone and Morphine on the sensation of pain?

Decrease discomfort by increasing the tolerance to pain Signup and view all the answers

What is the mechanism of action of Capsaicin?

Acting as a potent receptor agonist (TRPV1) Signup and view all the answers

Why should Duloxetine and Venlafaxine be used cautiously in patients with cardiac disease?

Because they can increase blood pressure and cardiac conduction abnormalities Signup and view all the answers

What is the mechanism of action of Tramadol in reducing neuropathic pain?

Inhibiting serotonin and norepinephrine reuptake, and acting as a µ-opioid agonist Signup and view all the answers

What is the effect of Lidocaine patches on neuropathic pain?

Reduce spontaneous ectopic nerve discharge Signup and view all the answers

What is the characteristic of Capsaicin molecule?

Produce the same sensation that excessive heat or abrasive damage would cause Signup and view all the answers

Neuropathic Pain and Nociceptive Pain Types

Questions and Answers

What is the primary cause of radicular pain?

What is visceral pain often described as?

Which of the following is NOT a cause of neuropathic pain?

What is the term for an increase in the perception of pain generated by a stimulus that causes pain?

What is the primary focus of neuropathic pain management?

Which of the following is a symptom of neuropathic pain?

Which medication is most effective in reducing neuropathic pain?

What is the mechanism of action of lidocaine patches in reducing neuropathic pain?

What is the action of capsaicin on the TRPV1 receptor?

What is the additional effect of tramadol that contributes to its analgesic properties in neuropathic pain?

What is the common side effect of duloxetine and venlafaxine that necessitates caution in patients with cardiac disease?

What is the effect of oxycodone and morphine on the sensation of pain?

What is the mechanism of action of Tricyclic Antidepressants in relation to serotonin and noradrenaline?

Which of the following conditions is Tricyclic Antidepressants contraindicated in?

What is the target of Gabapentin and Pregabalin in the treatment of pain?

What is the effect of Gabapentin and Pregabalin on Ca²+ influx to the cells?

Which of the following is NOT a first-line treatment for painful neuropathy?

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in relation to serotonin and norepinephrine?

What is the primary mechanism of action of Lidocaine patches in reducing neuropathic pain?

What is the effect of Capsaicin on the sensation of temperature?

Why should Duloxetine and Venlafaxine be used cautiously in patients with cardiac disease?

What is the additional mechanism of action of Tramadol that contributes to its analgesic properties in neuropathic pain?

What is the primary effect of Oxycodone and Morphine on the sensation of pain?

What is the primary mechanism of action of Capsaicin?

What is the effect of Amitriptyline on cholinergic, adrenergic, and histaminergic receptors and ionic channels?

What type of pain occurs when pain receptors in tissues are stimulated?

Which of the following is a cause of neuropathic pain?

Which of the following medications is used to treat pain following spinal cord injury?

What is the binding site of Gabapentin and Pregabalin in the treatment of pain?

What is the characteristic of visceral pain?

What is the focus of neuropathic pain management?

What is the side effect of Gabapentin and Pregabalin that is related to movement?

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in relation to serotonin and norepinephrine?

What is the term for pain due to a stimulus that does not normally provoke pain?

In which patients are Tricyclic Antidepressants contraindicated?

Which of the following is a sign of neuropathic pain?

What is the result of nerve injury or diseases such as diabetes, shingles, or cancer?

What is the characteristic of pain that occurs when pain receptors in internal organs are stimulated?

What is the focus of neuropathic pain management?

What is the term for pins and needles sensation?

What is the result of pain receptors in tissues being stimulated?

What is the term for an increase in the perception of pain generated by a stimulus that causes pain?

What is the mechanism of action of Tricyclic Antidepressants (TCAs) in terms of serotonin and noradrenaline?

What is the common side effect of Gabapentin and Pregabalin that is related to the central nervous system?

Which of the following medications is used to treat neuropathic pain by binding to the alpha-2 delta subunit of calcium channels?

What is the contraindication for Tricyclic Antidepressants (TCAs) in terms of cardiac conditions?

What is the mechanism of action of Serotonin Noradrenaline Reuptake Inhibitors (SNRIs) in terms of serotonin and noradrenaline?

What is the indication for the use of strong opioids, such as oxycodone and tramadol, in the treatment of neuropathic pain?

What is the primary effect of Oxycodone and Morphine on the sensation of pain?

What is the mechanism of action of Capsaicin?

Why should Duloxetine and Venlafaxine be used cautiously in patients with cardiac disease?

What is the mechanism of action of Tramadol in reducing neuropathic pain?

What is the effect of Lidocaine patches on neuropathic pain?

What is the characteristic of Capsaicin molecule?

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