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Antidepressants and Neuropathic Pain Management

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Antidepressants and Neuropathic Pain Management

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Questions and Answers

What is the primary mechanism of action of tricyclic antidepressants in treating neuropathic pain?

Inhibiting the reuptake of norepinephrine and serotonin (correct)

Stimulating the release of norepinephrine and serotonin

Inhibiting the breakdown of norepinephrine and serotonin

Enhancing the degradation of norepinephrine and serotonin

Which of the following tricyclic antidepressants is commonly used to treat neuropathic pain?

Citalopram

Fluoxetine

Amitriptyline (correct)

Paroxetine

What neurotransmitters are affected by tricyclic antidepressants in the treatment of neuropathic pain?

GABA and glutamate

Norepinephrine and serotonin (correct)

Acetylcholine and histamine

Dopamine and serotonin

What is the primary therapeutic use of imipramine?

Treating depression Signup and view all the answers

Which of the following is NOT a tricyclic antidepressant?

Fluoxetine Signup and view all the answers

What is the effect of tricyclic antidepressants on norepinephrine and serotonin?

They inhibit the reuptake of norepinephrine and serotonin. Signup and view all the answers

What is a common use of amitriptyline and doxepin?

Relieving neuropathic pain. Signup and view all the answers

What is imipramine commonly used to treat?

Depression. Signup and view all the answers

How do tricyclic antidepressants affect neurotransmitter levels?

They allow neurotransmitters to stay in the synapse for longer. Signup and view all the answers

What is the class of antidepressants that includes amitriptyline, doxepin, and imipramine?

Tricyclic antidepressants. Signup and view all the answers

Study Notes

Tricyclic Antidepressants

Used in the treatment of neuropathic pain
Examples of tricyclic antidepressants include:
- Amitriptyline
- Doxepin
- Imipramine
Mechanism of action: inhibit the reuptake of:
- Norepinephrine
- Serotonin

Tricyclic Antidepressants

Used in the treatment of neuropathic pain
Examples of tricyclic antidepressants include:
- Amitriptyline
- Doxepin
- Imipramine
Mechanism of action: inhibit the reuptake of:
- Norepinephrine
- Serotonin

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Description

This quiz covers the use of tricyclic antidepressants, such as amitriptyline, doxepin, and imipramine, in the treatment of neuropathic pain by inhibiting the reuptake of norepinephrine and serotonin.