Antidepressants and Neuropathic Pain Management
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Questions and Answers

What is the primary mechanism of action of tricyclic antidepressants in treating neuropathic pain?

  • Inhibiting the reuptake of norepinephrine and serotonin (correct)
  • Stimulating the release of norepinephrine and serotonin
  • Inhibiting the breakdown of norepinephrine and serotonin
  • Enhancing the degradation of norepinephrine and serotonin

Which of the following tricyclic antidepressants is commonly used to treat neuropathic pain?

  • Citalopram
  • Fluoxetine
  • Amitriptyline (correct)
  • Paroxetine

What neurotransmitters are affected by tricyclic antidepressants in the treatment of neuropathic pain?

  • GABA and glutamate
  • Norepinephrine and serotonin (correct)
  • Acetylcholine and histamine
  • Dopamine and serotonin

What is the primary therapeutic use of imipramine?

<p>Treating depression (D)</p> Signup and view all the answers

Which of the following is NOT a tricyclic antidepressant?

<p>Fluoxetine (A)</p> Signup and view all the answers

What is the effect of tricyclic antidepressants on norepinephrine and serotonin?

<p>They inhibit the reuptake of norepinephrine and serotonin. (D)</p> Signup and view all the answers

What is a common use of amitriptyline and doxepin?

<p>Relieving neuropathic pain. (C)</p> Signup and view all the answers

What is imipramine commonly used to treat?

<p>Depression. (B)</p> Signup and view all the answers

How do tricyclic antidepressants affect neurotransmitter levels?

<p>They allow neurotransmitters to stay in the synapse for longer. (B)</p> Signup and view all the answers

What is the class of antidepressants that includes amitriptyline, doxepin, and imipramine?

<p>Tricyclic antidepressants. (D)</p> Signup and view all the answers

Study Notes

Tricyclic Antidepressants

  • Used in the treatment of neuropathic pain
  • Examples of tricyclic antidepressants include:
    • Amitriptyline
    • Doxepin
    • Imipramine
  • Mechanism of action: inhibit the reuptake of:
    • Norepinephrine
    • Serotonin

Tricyclic Antidepressants

  • Used in the treatment of neuropathic pain
  • Examples of tricyclic antidepressants include:
    • Amitriptyline
    • Doxepin
    • Imipramine
  • Mechanism of action: inhibit the reuptake of:
    • Norepinephrine
    • Serotonin

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Description

This quiz covers the use of tricyclic antidepressants, such as amitriptyline, doxepin, and imipramine, in the treatment of neuropathic pain by inhibiting the reuptake of norepinephrine and serotonin.

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