Antidepressants and Neuropathic Pain Management

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Questions and Answers

Which neurotransmitters are inhibited in their reuptake by tricyclic antidepressants?

  • GABA and norepinephrine
  • Norepinephrine and serotonin (correct)
  • Acetylcholine and dopamine
  • Dopamine and serotonin

What class of drugs does amitriptyline belong to?

  • Tricyclic antidepressants (correct)
  • Monoamine oxidase inhibitors
  • Benzodiazepines
  • Selective serotonin reuptake inhibitors

Which condition is specifically mentioned as being treated by tricyclic antidepressants?

  • Neuropathic pain (correct)
  • Anxiety disorders
  • Bipolar disorder
  • Schizophrenia

Which of the following is NOT a tricyclic antidepressant?

<p>Citalopram (A)</p> Signup and view all the answers

Which mechanism is shared by tricyclic antidepressants?

<p>Inhibition of norepinephrine and serotonin reuptake (B)</p> Signup and view all the answers

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Study Notes

Antidepressants - Tricyclics

  • Tricyclic antidepressants, such as amitriptyline, doxepin, and imipramine, inhibit the reuptake of two neurotransmitters: norepinephrine and serotonin.
  • This mechanism of action makes them effective in the treatment of neuropathic pain.
  • They are classified as noradrenergic and serotonergic antidepressants, indicating their influence on the levels of norepinephrine and serotonin in the brain.

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