12 Questions
What type of antibody is abundantly produced in mucosal tissues?
Immunoglobulin A (IgA)
What cells make up the follicles in the lymph nodes?
B-lymphocytes (B-cells)
How do naïve B and T cells enter the lymph node?
High endothelial venule (HEV)
How do dendritic cells enter the lymph node?
Afferent lymphatic vessels
What happens to activated T cells in the lymph node?
They exit the nodes, enter the bloodstream, and migrate to peripheral tissues
Which of the following plays a key role in immune defense in the small intestine?
Peyer's patches
Where are naïve T cells initially localized or generated?
Thymus
After their development, where do naïve T cells enter through to reach lymph nodes?
High endothelial venules (HEV)
During the effector stage, which type of T cells migrate to peripheral sites of infection?
Effector T cells
Which tissues do effector T cells migrate to during the effector stage?
Mucosal and cutaneous lymphoid tissues
As individuals age, what compensates for the reduced output of new, naïve T cells from the thymus?
Gradual accumulation of memory cells
Which tissues have the greatest number of lymphocytes?
Lymph Nodes, Spleen, Bone Marrow, Intestines
Explore the localization of naïve T cells and their transition to the effector stage in the immune system. Learn about the development of naïve T cells in the thymus and their role as effector T cells during immune responses.
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