Naïve T Cell Activation Quiz
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Questions and Answers

Which molecule is responsible for making pores on the surface of target cells?

  • Perforins (correct)
  • TCR
  • CD40
  • B7
  • What type of cell presents an identical peptide on MHC I to the CD8+ T cell?

  • B cell
  • Naïve Th cell
  • Target cell (correct)
  • Macrophage
  • Which type of cell will a Th0 cell become based on cytokine signal?

  • Naïve Th cell
  • CD8+ T cell
  • B cell
  • Effector cell (Th1, Th2, Th17) (correct)
  • Which molecule is involved in the interaction of CD4 and MHC II?

    <p>TCR</p> Signup and view all the answers

    Which molecule is responsible for the ligand-receptor type interaction of B7 and CD28?

    <p>CD28</p> Signup and view all the answers

    Which signaling molecule is assumed to cause a Th0 cell to become a Th2 cell?

    <p>IL4</p> Signup and view all the answers

    Which cells release oxidative enzymes into the target cell?

    <p>CTL</p> Signup and view all the answers

    Which molecule is involved in the interaction of pMHC II and TCR?

    <p>TCR</p> Signup and view all the answers

    Which molecule is responsible for the release of other soluble factors such as TNF?

    <p>CTL</p> Signup and view all the answers

    Which molecule is involved in the interaction of CD40 and CD40?

    <p>CD40</p> Signup and view all the answers

    Which molecule is responsible for the ligand-receptor type interaction of CD40 and CD40?

    <p>CD40</p> Signup and view all the answers

    Which molecule is involved in the immunological synapse?

    <p>CD4 * MHC II</p> Signup and view all the answers

    Which T cell subset is responsible for cytokine production and cell-to-cell contact for activation?

    <p>Helper (CD3+, CD4+)</p> Signup and view all the answers

    Which type of cells recognize microbes via various receptors including pattern-recognition receptors (PRR) and present peptides to T cells for recognition?

    <p>Dendritic cells (DC)</p> Signup and view all the answers

    What type of mitogen triggers ALL (T or B) lymphocytes to activation, undergo blast transformation, and cause resting cells to divide?

    <p>Pokeweed mitogen</p> Signup and view all the answers

    What is the function of a superantigen?

    <p>Stimulate lymphocytes by binding to the TCR, outside of the antigen-binding site</p> Signup and view all the answers

    What is the fate of mature T cells after encountering their specific antigen and receiving appropriate accessory signals?

    <p>Proliferate and differentiate into effector or memory cells</p> Signup and view all the answers

    Which T cell subset is responsible for cytokine production and cell-to-cell contact for suppression?

    <p>Regulatory (CD3+, CD4+)</p> Signup and view all the answers

    What triggers blast transformation in T cells?

    <p>Concanavalin A (con A)</p> Signup and view all the answers

    Which molecule derived from microbial organisms stimulates lymphocytes by binding to the TCR, outside of the antigen-binding site?

    <p>Staphylococcal protein enterotoxin B (SEB or SE)</p> Signup and view all the answers

    What is the primary function of dendritic cells (DC) in the immune response?

    <p>Recognize microbes and present peptides to T cells for recognition</p> Signup and view all the answers

    What is the role of polyclonal mitogens in triggering lymphocytes?

    <p>Trigger ALL (T or B) lymphocytes to activation and division</p> Signup and view all the answers

    What is the consequence of mature T cells encountering their specific antigen and receiving appropriate accessory signals?

    <p>Proliferation and differentiation into effector or memory cells</p> Signup and view all the answers

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