Naïve T Cell Activation Quiz
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Questions and Answers

Which molecule is responsible for making pores on the surface of target cells?

  • Perforins (correct)
  • TCR
  • CD40
  • B7

What type of cell presents an identical peptide on MHC I to the CD8+ T cell?

  • B cell
  • Naïve Th cell
  • Target cell (correct)
  • Macrophage

Which type of cell will a Th0 cell become based on cytokine signal?

  • Naïve Th cell
  • CD8+ T cell
  • B cell
  • Effector cell (Th1, Th2, Th17) (correct)

Which molecule is involved in the interaction of CD4 and MHC II?

<p>TCR (B)</p> Signup and view all the answers

Which molecule is responsible for the ligand-receptor type interaction of B7 and CD28?

<p>CD28 (C)</p> Signup and view all the answers

Which signaling molecule is assumed to cause a Th0 cell to become a Th2 cell?

<p>IL4 (D)</p> Signup and view all the answers

Which cells release oxidative enzymes into the target cell?

<p>CTL (A)</p> Signup and view all the answers

Which molecule is involved in the interaction of pMHC II and TCR?

<p>TCR (A)</p> Signup and view all the answers

Which molecule is responsible for the release of other soluble factors such as TNF?

<p>CTL (A)</p> Signup and view all the answers

Which molecule is involved in the interaction of CD40 and CD40?

<p>CD40 (B)</p> Signup and view all the answers

Which molecule is responsible for the ligand-receptor type interaction of CD40 and CD40?

<p>CD40 (A)</p> Signup and view all the answers

Which molecule is involved in the immunological synapse?

<p>CD4 * MHC II (B)</p> Signup and view all the answers

Which T cell subset is responsible for cytokine production and cell-to-cell contact for activation?

<p>Helper (CD3+, CD4+) (C)</p> Signup and view all the answers

Which type of cells recognize microbes via various receptors including pattern-recognition receptors (PRR) and present peptides to T cells for recognition?

<p>Dendritic cells (DC) (D)</p> Signup and view all the answers

What type of mitogen triggers ALL (T or B) lymphocytes to activation, undergo blast transformation, and cause resting cells to divide?

<p>Pokeweed mitogen (C)</p> Signup and view all the answers

What is the function of a superantigen?

<p>Stimulate lymphocytes by binding to the TCR, outside of the antigen-binding site (C)</p> Signup and view all the answers

What is the fate of mature T cells after encountering their specific antigen and receiving appropriate accessory signals?

<p>Proliferate and differentiate into effector or memory cells (C)</p> Signup and view all the answers

Which T cell subset is responsible for cytokine production and cell-to-cell contact for suppression?

<p>Regulatory (CD3+, CD4+) (D)</p> Signup and view all the answers

What triggers blast transformation in T cells?

<p>Concanavalin A (con A) (D)</p> Signup and view all the answers

Which molecule derived from microbial organisms stimulates lymphocytes by binding to the TCR, outside of the antigen-binding site?

<p>Staphylococcal protein enterotoxin B (SEB or SE) (D)</p> Signup and view all the answers

What is the primary function of dendritic cells (DC) in the immune response?

<p>Recognize microbes and present peptides to T cells for recognition (C)</p> Signup and view all the answers

What is the role of polyclonal mitogens in triggering lymphocytes?

<p>Trigger ALL (T or B) lymphocytes to activation and division (C)</p> Signup and view all the answers

What is the consequence of mature T cells encountering their specific antigen and receiving appropriate accessory signals?

<p>Proliferation and differentiation into effector or memory cells (B)</p> Signup and view all the answers

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